Proteome data to explore the axolotl limb regeneration capacity at neotenic and metamorphic stages

dc.contributor.authorDemircan, Turan
dc.contributor.authorSibai, Mustafa
dc.contributor.authorAltuntaş, Ebru
dc.date.accessioned2020-07-29T12:49:02Z
dc.date.available2020-07-29T12:49:02Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Rejeneratif ve Restoratif Tıp Araştırmaları Merkezi (REMER)
dc.description.abstractThe presented data article reports protein expression profiles during a time course of limb regeneration in the highly regenerative neotenic and regeneration-deficient metamorphic axolotl (Ambystoma mexicanum). A protein database was first generated from transcriptome data, which was used concomitantly with nanoLC-MS/MS to identify and assess significant changes of protein levels among 0, 1, 4, and 7 days post-amputation (dpa) in both animal stages, yielding a total of 714 significant differentially expressed proteins. Gene ontology categories of these identified proteins were examined in terms of biological processes, molecular function and cellular components. Innate clustering patterns of the samples were investigated using hierarchical clustering and were visualized on a heatmap. The data reported here constitutes an extension of "Comparison of protein expression profile of limb regeneration between neotenic and metamorphic axolotl" article Sibai et al., 2019 [1]. The associated mass spectrometry raw data have been deposited in the ProteomeXchange Consortium (http://proteomecentral.proteomexchange.org) with the dataset identifier PXD014806.
dc.identifier.citationDemircan, T., Sibai, M. ve Altuntaş, E. (2020). Proteome data to explore the axolotl limb regeneration capacity at neotenic and metamorphic stages. Data in Brief, 29. https://dx.doi.org/10.1016/j.dib.2020.105179
dc.identifier.doi10.1016/j.dib.2020.105179
dc.identifier.issn2352-3409
dc.identifier.scopusqualityQ4
dc.identifier.urihttps://dx.doi.org/10.1016/j.dib.2020.105179
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5647
dc.identifier.volume29
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofData in Briefen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectAxolotl
dc.subjectRegeneration
dc.subjectProteomics
dc.subjectLC-MS/MS
dc.subjectMetamorphosis
dc.titleProteome data to explore the axolotl limb regeneration capacity at neotenic and metamorphic stages
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Yükleniyor...
Küçük Resim
İsim:
Demircan, Turan-2020.pdf
Boyut:
1.26 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama: