Frontocentral delta and theta oscillatory responses are sensitive to sleep deprivation during a working memory task

Basit Öğe Kaydı
dc.contributor.authorYırıkoğulları, Harun
dc.contributor.authorDalmızrak, Esra
dc.contributor.authorGüntekin, Bahar
dc.date.accessioned2026-05-11T09:12:23Z
dc.date.available2026-05-11T09:12:23Z
dc.date.issued2025
dc.departmentİstanbul Medipol Üniversitesi, Rektörlük, Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, Sinirbilim Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Biyofizik Ana Bilim Dalı
dc.description.abstractSleep deprivation has become a severe public health problem in modern societies. Negative consequences of prolonged wakefulness on cognitive abilities have been demonstrated and working memory is one of the main cognitive functions that can be affected by sleep deprivation. This study aims to investigate the effects of sleep deprivation on working memory through EEG event-related oscillations. Thirty healthy young adult university students and graduates were included in this study (15 rested control – 15 sleep-deprived). A 2-back task was used to evaluate working memory, and both groups performed the task during EEG recording. The sleep-deprived (SD) group was required to stay awake for 24 h, and then the EEG session was conducted. The rested control (RC) subjects participated in the morning after a regular night's sleep. Event-related power and phase-locking analyses were applied, and delta (1–3.5 Hz), theta (4–6.5 Hz) and alpha (8–13 Hz) frequencies were investigated in the time-frequency domain. In the 2-back task, significantly prolonged reaction times were observed in the SD group. However, the decrease in accuracy rate was not significant. The EEG analyses revealed that the SD group had decreased frontocentral event-related delta and theta power responses after the presentation of stimuli. Moreover, task accuracy was positively correlated with the left frontocentral delta power in the SD group, and theta power in the RCs. Thus, we propose that the adverse effects of sleep deprivation on working memory can be observed through low-frequency oscillatory responses in the brain.
dc.identifier.citationYırıkoğulları, H., Dalmızrak, E. ve Güntekin, B. (2025). Frontocentral delta and theta oscillatory responses are sensitive to sleep deprivation during a working memory task. Clinical EEG and Neuroscience, 56(6), 497-506. http://dx.doi.org/10.1177/15500594251316914
dc.identifier.doi10.1177/15500594251316914
dc.identifier.endpage506
dc.identifier.issue6
dc.identifier.pmid39905900
dc.identifier.scopus2-s2.0-85217172363
dc.identifier.scopusqualityQ2
dc.identifier.startpage497
dc.identifier.urihttp://dx.doi.org/10.1177/15500594251316914
dc.identifier.uri1550-0594
dc.identifier.urihttps://hdl.handle.net/20.500.12511/13442
dc.identifier.volume56
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYırıkoğulları, Harun
dc.institutionauthorDalmızrak, Esra
dc.institutionauthorGüntekin, Bahar
dc.institutionauthorid0000-0002-0384-2671
dc.institutionauthorid0000-0002-6926-5176
dc.institutionauthorid0000-0002-0860-0524
dc.language.isoen
dc.relation.ispartofClinical EEG and Neuroscience
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDelta Power
dc.subjectEEG
dc.subjectEvent-Related Oscillations
dc.subjectSleep Deprivation
dc.subjectTheta Power
dc.subjectTime-Frequency Analysis
dc.subjectWorking Memory
dc.titleFrontocentral delta and theta oscillatory responses are sensitive to sleep deprivation during a working memory task
dc.typeArticle

Dosyalar

Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.17 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Sağlık Bilimleri Enstitüsü Diğer Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu