The prevalence and topographic distribution of penile calcification in a large cohort: a retrospective cross-sectional study

dc.contributor.authorBaran, Caner
dc.contributor.authorÇulha, Mehmet Gökhan
dc.contributor.authorBayraktarlı, Recep Yılmaz
dc.contributor.authorÖzgür, Berat Cem
dc.contributor.authorÇalık, Gökhan
dc.contributor.authorGüzelburç, Vahit
dc.contributor.authorKadıoğlu, Ateş
dc.date.accessioned2025-06-11T09:55:02Z
dc.date.available2025-06-11T09:55:02Z
dc.date.issued2024
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı
dc.description.abstractThe prevalence of penile calcification in the population remains uncertain. This retrospective multicenter study aimed to determine the prevalence and characteristics of penile calcification in a large cohort of male patients undergoing non-contrast pelvic tomography. A total of 14 545 scans obtained from 19 participating centers between 2016 and 2022 were retrospectively analyzed within a 3-months period. Eligible scans (n = 12 709) were included in the analysis. Patient age, penile imaging status, presence of calcified plaque, and plaque measurements were recorded. Statistical analysis was performed to assess the relationships between calcified plaque, patient age, plaque characteristics, and plaque location. Among the analyzed scans, 767 (6.04%) patients were found to have at least one calcified plaque. Patients with calcified plaque had a significantly higher median age (64 years (IQR 56–72)) compared to those with normal penile evaluation (49 years (IQR 36-60) (p < 0.001). Of the patients with calcified plaque, 46.4% had only one plaque, while 53.6% had multiple plaques. There was a positive correlation between age and the number of plaques (r = 0.31, p < 0.001). The average dimensions of the calcified plaques were as follows: width: 3.9 ± 5 mm, length: 5.3 ± 5.2 mm, height: 3.5 ± 3.2 mm, with an average plaque area of 29 ± 165 mm² and mean plaque volume of 269 ± 3187 mm³. Plaques were predominantly located in the proximal and mid-penile regions (44.1% and 40.5%, respectively), with 77.7% located on the dorsal side of the penis. The hardness level of plaques, assessed by Hounsfield units, median of 362 (IQR 250–487) (range: 100–1400). Patients with multiple plaques had significantly higher Hounsfield unit values compared to those with a single plaque (p = 0.003). Our study revealed that patients with calcified plaques are older and have multiple plaques predominantly located on the dorsal and proximal side of the penis.
dc.identifier.citationBaran, C., Çulha, M. G., Bayraktarlı, R. Y., Özgür, B. C., Çalık, G., Güzelburç, V. ... Kadıoğlu, A. (2024). The prevalence and topographic distribution of penile calcification in a large cohort: a retrospective cross-sectional study. International Journal of Impotence Research, 36(6), 576-580. http://dx.doi.org/10.1038/s41443-023-00758-6
dc.identifier.doi10.1038/s41443-023-00758-6
dc.identifier.endpage580
dc.identifier.issn0955-9930
dc.identifier.issn1476-5489
dc.identifier.issue6
dc.identifier.pmid37660216
dc.identifier.scopus2-s2.0-85169305860
dc.identifier.scopusqualityQ2
dc.identifier.startpage576
dc.identifier.urihttp://dx.doi.org/10.1038/s41443-023-00758-6
dc.identifier.urihttps://hdl.handle.net/20.500.12511/12943
dc.identifier.volume36
dc.identifier.wosWOS:001060807000001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇalık, Gökhan
dc.institutionauthorGüzelburç, Vahit
dc.institutionauthorid0000-0002-9976-9666
dc.institutionauthorid0000-0001-9988-2944
dc.language.isoen
dc.relation.ispartofInternational Journal of Impotence Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPenis Disease
dc.subjectCross-Sectional Studies
dc.subjectRetrospective Studies
dc.subjectPenile Calcification
dc.titleThe prevalence and topographic distribution of penile calcification in a large cohort: a retrospective cross-sectional study
dc.typeArticle

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