Effect of pulmonary vein anatomy and pulmonary vein diameters on outcome of cryoballoon catheter ablation for atrial fibrillation

dc.authorid0000-0002-4607-5724
dc.authorid0000-0001-9975-5507
dc.authorid0000-0003-1919-3183
dc.authorid0000-0001-5825-8627
dc.contributor.authorGüler, Ekrem
dc.contributor.authorBabür Güler, Gamze
dc.contributor.authorDemir, Gültekin Günhan
dc.contributor.authorKızılırmak, Filiz
dc.contributor.authorGüneş, Hacı Murat
dc.contributor.authorBarutçu, İrfan
dc.contributor.authorKılıçaslan, Fethi
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T20:02:19Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T20:02:19Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.descriptionWOS: 000358697100011
dc.descriptionPubMed ID: 25974075
dc.description.abstractBackgroundIn this study, we aimed to determine pulmonary vein (PV) variation patterns in patients undergoing cryoballoon ablation for atrial fibrillation (AF) and their impacts on procedural success and recurrence and also to identify predictors for recurrence. MethodsWe enrolled 54 patients with AF and having symptoms despite medical therapy. Prior to the procedure, PV variation and left atrium (LA) size were evaluated in all patients by computed tomography scan. Ablation procedure was performed with single balloon and predictors for AF recurrence were determined. ResultsThe study population consisted of 54 patients (male: 50 [27%], mean age: 53 12) with AF. Paroxysmal AF and persistent AF were detected in 55.6% (30) and 44.4% (24) of the patients, respectively. Mean procedural and fluoroscopy times were 73 +/- 19 minutes and 16 +/- 4 minutes, respectively. The number of the patients with PV variation of right pulmonary vein (RPV) with >2 ostia and accessory PV was 27.8% (15) and 18.5% (10). During the follow-up, 20.4% (11) of patients had AF recurrence. Patients with recurrence had greater transverse LA size (62 +/- 6 mm vs 57 +/- 5 mm, P: 0014), longitudinal LA size (65 +/- 5 mm vs 61 +/- 6 mm, P: 0025), LA volume (78 +/- 17 mL vs 65 +/- 14 mL, P: 0011), fluoroscopy time (20.4 +/- 4.6 minutes vs 15.7 +/- 3.5 minutes, P: 0001), RPV with >2 ostia (72.7% vs 27.3%, P: 0001), right upper pulmonary vein (RUPV) diameter (21.6 +/- 2.8 cm vs 15.8 +/- 2.1 cm; P < 0001), and persistent AF (33.3% vs 66.7%, P: 0046). In multivariate analysis, RUPV diameter (: 1006; P: 0010; odds ratio [OR]: 2736; 95% confidence interval [CI]: [1267-5906]) and fluoroscopy time (: 0327; P: 0050; OR: 1386; 95% CI: [1000-1921]) were determined as independent predictors for AF recurrence. ConclusionsTransverse and longitudinal LA size, LA volume, fluoroscopy time, presence of persistent AF, RUPV size, and the number of RPV ostia are associated with AF recurrence following cryoballoon-based ablation. RUPV size and fluoroscopy time are predictors for recurrence.
dc.identifier.citationGüler, E., Babür Güler, G., Demir, G. G., Kızılırmak, F., Güneş, H. M., Barutçu, İ. ve Kılıçaslan, F. (2015). Effect of pulmonary vein anatomy and pulmonary vein diameters on outcome of cryoballoon catheter ablation for atrial fibrillation. Pacing and Clinical Electrophysiology, 38(8), 989-996. https://dx.doi.org/10.1111/pace.12660
dc.identifier.doi10.1111/pace.12660
dc.identifier.endpage996
dc.identifier.issn0147-8389
dc.identifier.issn1540-8159
dc.identifier.issue8
dc.identifier.scopusqualityQ2
dc.identifier.startpage989
dc.identifier.urihttps://dx.doi.org/10.1111/pace.12660
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3617
dc.identifier.volume38
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofPacing and Clinical Electrophysiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectAtrial Fibrillation
dc.subjectPulmonary Vein Isolation
dc.subjectPulmonary Vein Variation
dc.subjectCryoballoon
dc.subjectRecurrence
dc.titleEffect of pulmonary vein anatomy and pulmonary vein diameters on outcome of cryoballoon catheter ablation for atrial fibrillation
dc.typeArticle

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