Infusion jet flow control in neonatal double lumen cannulae

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dc.authorid0000-0001-5485-5440
dc.contributor.authorRasooli, Reza
dc.contributor.authorYıldız, Yahya
dc.contributor.authorJamil, Muhammad
dc.contributor.authorPekkan, Kerem
dc.date.accessioned2020-03-23T10:40:00Z
dc.date.available2020-03-23T10:40:00Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.description.abstractClinical success of extracorporeal membrane oxygenation (ECMO) depends on the proper venous cannulation. Venovenous (VV) ECMO is the preferred clinical intervention as it provides a single-site access by utilizing a VV double lumen cannula (VVDLC) with a higher level of mobilization and physical rehabilitation. Concurrent venous blood drainage and oxygenated blood infusion in the right atrium at the presence of the cannula makes the flow dynamics complex where potential mixing of venous and oxygenated blood can drastically decreases the overall performance of ECMO. There are no studies focusing the neonatal and pediatric populations, in which the flow related effects are of paramount importance due to the small atrium size. In this study, fluid dynamics of infusion outflow jet for two commercially available neonatal VVDLC is analyzed using particle image velocimetry. Moreover, six new designs are proposed for the infusion channel geometry and compared. Important flow parameters such as flow turning angle (FTA), velocity decay, potential core and turbulent intensity are investigated for the proposed models. The experiments showed that the outflow parameters of commercial cannulae such as FTA are strongly dependent on the operating Re number. This may result in a drastic efficiency reduction for cannula operating at off-design flow conditions. Moreover, the infusion outlet tip structure and jet internal guiding pathway (JIGP) was observed to greatly affect the outflow flow features. This is of paramount importance since the anatomical positioning of the cannula and the infusion outlet is strongly dependent on the outflow properties such as FTA.
dc.description.sponsorshipEuropean Research Council (ERC)en_US
dc.identifier.citationRasooli, R., Yıldız, Y., Jamil, M. ve Pekkan, K. (2020). Infusion jet flow control in neonatal double lumen cannulae. Journal of Biomechanical Engineering, 142(5). http://doi.org/10.1115/1.4044548
dc.identifier.doi10.1115/1.4044548
dc.identifier.issue5
dc.identifier.scopusqualityQ3
dc.identifier.urihttp://doi.org/10.1115/1.4044548
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5074
dc.identifier.volume142
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAmerican Society of Mechanical Engineers
dc.relation.ispartofJournal of Biomechanical Engineeringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/1003
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/115E690
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/118S108
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectJet Flow
dc.subjectNeonatal Double Lumen Cannulae
dc.titleInfusion jet flow control in neonatal double lumen cannulae
dc.typeArticle

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