Frequency of hematological findings associated with severe plasma vitamin B12 deficiency in infants and adolescents

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dc.authorid0000-0002-6299-7067
dc.contributor.authorAtay, Enver
dc.contributor.authorAkın, Mehmet
dc.contributor.authorÖzhan, Bayram
dc.contributor.authorÖztekin, Osman
dc.contributor.authorKarakuş, Yasin Tuğrul
dc.contributor.authorErdoğan, Fırat
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:51:18Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:51:18Z
dc.date.issued2014
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000342857400016
dc.descriptionPubMed ID: 24779301
dc.description.abstractBackground: The aim of this study was to determine the hematological status of severe vitamin B12 deficiency in infants and adolescents. Methods: This study involved 95 infants and 117 adolescents with severe plasma vitamin B12 deficiency (< 120 pg/mL) and normal plasma folate and ferritin. Infants were aged between one and 24 months. Adolescents were aged between 11 and 17 years. Results: Macrocytic anemia was associated with nine (9.5%) out of 95 infants with severe vitamin B12 deficiency. Neutropenia was found in 16 (16.8%) out of 95 infants with severe vitamin B12 deficiency. Thrombocytopenia was not found in 95 infants with severe vitamin B12 deficiency. Macrocytic anemia was found in two (1.7%) out of 117 adolescents with a severe vitamin B12 deficiency. Neutropenia was associated in one (0.8%) out of 117 adolescents with severe vitamin B12 deficiency. Thrombocytopenia was not found in 117 adolescents with severe vitamin B12 deficiency. Conclusions: Low clinical or hematological findings for B12 deficiency in infants and adolescents living in regions at risk, such as those with low consumption of meat and other animal products warrant the measurement of vitamin B12 level.
dc.identifier.citationAtay, E., Akın, M., Özhan, B., Öztekin, O., Karakuş, Y. T. ve Erdoğan, F. (2014). Frequency of hematological findings associated with severe plasma vitamin B12 deficiency in infants and adolescents. Clinical Laboratory, 60(4), 659-662. https://dx.doi.org/10.7754/Clin.Lab.2013.130454
dc.identifier.doi10.7754/Clin.Lab.2013.130454
dc.identifier.endpage662
dc.identifier.issn1433-6510
dc.identifier.issue4
dc.identifier.scopusqualityQ2
dc.identifier.startpage659
dc.identifier.urihttps://dx.doi.org/10.7754/Clin.Lab.2013.130454
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2192
dc.identifier.volume60
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherClinical Laboratory Publication
dc.relation.ispartofClinical Laboratoryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCobalamin Deficiency
dc.subjectHematological Values
dc.subjectInfants
dc.subjectAdolescents
dc.titleFrequency of hematological findings associated with severe plasma vitamin B12 deficiency in infants and adolescents
dc.typeArticle

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