Virtual reality training helpful in motor and cognition in corticobasal syndrome: A case report PET study

dc.authorid0000-0002-5286-4981
dc.authorid0000-0002-7685-2766
dc.authorid0000-0003-4292-5717
dc.contributor.authorHajebrahimi, Farzin
dc.contributor.authorÇakır, Tansel
dc.contributor.authorHanoğlu, Lütfü
dc.date.accessioned2020-10-12T06:25:42Z
dc.date.available2020-10-12T06:25:42Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Bilimleri Fakültesi, Fizyoterapi ve Rehabilitasyon Bölümü
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nükleer Tıp Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı
dc.description.abstractCorticobasal syndrome (CBS) is a rare progressive neurodegenerative disease characterized by a combination of asymmetric motor symptoms and non-motor symptoms. CBS is poorly responsive to levodopa. Non-pharmacological strategies have been found to be useful as components of a multidisciplinary therapeutic approach for patients with CBS. The purpose of this study was to investigate the effects of virtual reality training in addressing symptoms of CBS. A 64-year-old man was clinically diagnosed as CBS one year after the onset of complaints. Positron emission tomography (PET) scan showed asymmetrical hypometabolism in the right thalamus and basal ganglia. The patient was evaluated for balance, gait, mobility, and cognition 1 week before, 1 week after, and 1 year after 6 weeks of training, 3 times weekly (18 sessions in total). All clinical outcomes and PET result had improved after the intervention; cognition and balance were maintained after 1 year. Additionally, the asymmetric hypometabolism, which had been detectable on the PET scan, became normal, and a relative improvement was noted in the visual evaluation of cortical involvement. Virtual reality may address different aspects of motor and cognition and possibly brain metabolic changes that can affect the course of the disease in patients with CBS.
dc.identifier.citationHajebrahimi, F., Çakır, T. ve Hanoğlu, L. (2020). Virtual reality training helpful in motor and cognition in corticobasal syndrome: A case report PET study. Case Reports in Neurology, 12(2), 238-246. https://dx.doi.org/10.1159/000508492
dc.identifier.doi10.1159/000508492
dc.identifier.endpage246
dc.identifier.issn1662-680X
dc.identifier.issue2
dc.identifier.scopusqualityQ4
dc.identifier.startpage238
dc.identifier.urihttps://dx.doi.org/10.1159/000508492
dc.identifier.urihttps://hdl.handle.net/20.500.12511/5906
dc.identifier.volume12
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofCase Reports in Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectCorticobasal Syndrome
dc.subjectVirtual Reality
dc.subjectAtypical Parkinson Syndrome
dc.subjectPET
dc.subjectCase Report
dc.titleVirtual reality training helpful in motor and cognition in corticobasal syndrome: A case report PET study
dc.typeArticle

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