Surface characterization, electrochemical properties and in vitro biological properties of Zn-deposited TiO2 nanotube surfaces

dc.authorid0000-0002-4257-8543
dc.authorid0000-0001-7944-5077
dc.contributor.authorDurdu, Salih
dc.contributor.authorCihan, Gizem
dc.contributor.authorYalçın, Emine
dc.contributor.authorÇavuşoğlu, Kültigin
dc.contributor.authorAltınkök, Atılgan
dc.contributor.authorSağcan, Hasan
dc.contributor.authorYurtsever, İlknur
dc.contributor.authorUsta, Metin
dc.date.accessioned2023-07-28T11:35:16Z
dc.date.available2023-07-28T11:35:16Z
dc.date.issued2023
dc.departmentİstanbul Medipol Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Laboratuvar Teknikleri Ana Bilim Dalı
dc.description.abstractIn this work, to improve antibacterial, biocompatible and bioactive properties of commercial pure titanium (cp-Ti) for implant applications, the Zn-deposited nanotube surfaces were fabricated on cp-Ti by using combined anodic oxidation (AO) and physical vapor deposition (PVD-TE) methods. Homogenous elemental distributions were observed through all surfaces. Moreover, Zn-deposited surfaces exhibited hydrophobic character while bare Ti surfaces were hydrophilic. Due to the biodegradable behavior of Zn on the nanotube surface, Zn-deposited nanotube surfaces showed higher corrosion current density than bare cp-Ti surface in SBF conditions as expected. In vitro biological properties such as cell viability, ALP activity, protein adsorption, hemolytic activity and antibacterial activity for Gram-positive and Gram-negative bacteria of all surfaces were investigated in detail. Cell viability, ALP activity and antibacterial properties of Zn-deposited nanotube surfaces were significantly improved with respect to bare cp-Ti. Moreover, hemolytic activity and protein adsorption of Zn-deposited nanotube surfaces were decreased. According to these results; a bioactive, biocompatible and antibacterial Zn-deposited nanotube surfaces produced on cp-Ti by using combined AO and PVD techniques can have potential for orthopedic and dental implant applications.
dc.identifier.citationDurdu, S., Cihan, G., Yalçın, E., Çavuşoğlu, K., Altınkök, A., Sağcan, H. ... Usta, M. (2023). Surface characterization, electrochemical properties and in vitro biological properties of Zn-deposited TiO2 nanotube surfaces. Scientific Reports, 13(1). https://dx.doi.org/10.1038/s41598-023-38733-2
dc.identifier.doi10.1038/s41598-023-38733-2
dc.identifier.issn2045-2322
dc.identifier.issue1
dc.identifier.pmid37452093
dc.identifier.scopus2-s2.0-85164755730
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://dx.doi.org/10.1038/s41598-023-38733-2
dc.identifier.urihttps://hdl.handle.net/20.500.12511/11275
dc.identifier.volume13
dc.identifier.wos001030642400017en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSağcan, Hasan
dc.institutionauthorYurtsever, İlknur
dc.language.isoen
dc.publisherNature Research
dc.relation.ispartofScientific Reportsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/118M766
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectTiO2 Nanotube Surfaces
dc.subjectVitro Biological Properties
dc.subjectElectrochemical Properties
dc.titleSurface characterization, electrochemical properties and in vitro biological properties of Zn-deposited TiO2 nanotube surfaces
dc.typeArticle

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