The effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy. An experimental study in rats
| dc.authorid | 0000-0003-0428-2511 | |
| dc.authorid | 0000-0002-9815-1848 | |
| dc.authorid | 0000-0002-9452-9276 | |
| dc.authorid | 0000-0001-6830-7701 | |
| dc.authorid | 0000-0002-2282-7207 | |
| dc.contributor.author | Özdenkaya, Yaşar | |
| dc.contributor.author | Ölmüşçelik, Oktay | |
| dc.contributor.author | Basım, Pelin | |
| dc.contributor.author | Saka, Burcu | |
| dc.contributor.author | Arslan, Naciye Çiğdem | |
| dc.date.accessioned | 2019-12-26T05:52:11Z | |
| dc.date.available | 2019-12-26T05:52:11Z | |
| dc.date.issued | 2019 | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Patoloji Ana Bilim Dalı | |
| dc.description.abstract | Purpose: To evaluate the effect of fibrin glue on staple-line leak after sleeve gastrectomy. Methods: Fourteen adult wistar rats 300 gr were randomized into two groups: Control group (n=7) and study group (n=7). All the rats underwent sleeve gastrectomy using lineer stapler. In the study group, fibrin glue was used to reinforce the staple-line. The rats were sacrificed 7 days after surgery. The stomach was resected, submerged in saline and exposed to excess pressure to obtain a burst pressure value. The gastric staple line was evaluated histopathologically according to the Ehrlich Hunt scale. The results of the two groups were compared. Results: The mean Ehrlich-Hunt scores for inflammation, fibroblastic activity and neo-angiogenesis were similar between the groups (p>0.05). Collagen deposition was significantly higher in study group (3.42±0.53) when compared with control group (2.57±0.78) (p=0.035). The mean burst pressure was 137.8±8.5 mmHg for control group and 135.0±8.1 mmHg for study group (p=0.536). Conclusion: Reinforcement of the staple-line with fibrin glue has no effect on the burst pressure after sleeve gastrectomy. More studies are needed to evaluate the precautions against leak after sleeve gastrectomy. | |
| dc.identifier.citation | Özdenkaya, Y., Ölmüşçelik, O., Basım, P., Saka, B. ve Arslan, N. Ç. (2019). The effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy. An experimental study in rats. Acta Cirurgica Brasileira, 34(8). http://doi.org/10.1590/s0102-865020190080000001 | |
| dc.identifier.doi | 10.1590/s0102-865020190080000001 | |
| dc.identifier.issn | 0102-8650 | |
| dc.identifier.issue | 8 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.uri | http://doi.org/10.1590/s0102-865020190080000001 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/4703 | |
| dc.identifier.volume | 34 | |
| dc.identifier.wosquality | Q4 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Ociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia | |
| dc.relation.ispartof | Acta Cirurgica Brasileira | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | Attribution 4.0 International | * |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/deed.en | * |
| dc.subject | Fibrin Tissue Adhesive | |
| dc.subject | Gastrectomy | |
| dc.subject | Rats | |
| dc.title | The effect of fibrin glue in preventing staple-line leak after sleeve gastrectomy. An experimental study in rats | |
| dc.type | Article |
