The effects of hemodialysis on tear osmolarity

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dc.authorid0000-0003-0668-3749
dc.contributor.authorTaşkapılı, Muhittin
dc.contributor.authorŞerefoğlu Çabuk, Kübra
dc.contributor.authorAydın, Rukiye
dc.contributor.authorAtalay, Kürşat
dc.contributor.authorKırgız, Ahmet
dc.contributor.authorSit, Dede
dc.contributor.authorKayabaşı, Hasan
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:58:50Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:58:50Z
dc.date.issued2015
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000365249700001
dc.descriptionPubMed ID: 26640702
dc.description.abstractAim. To determine the effects of hemodialysis (HD) on tear osmolarity and to define the blood biochemical tests correlating with tear osmolarity among patients with end stage renal disease (ESRD). Material-Method. Tear osmolarity of ESRD patients before and after the hemodialysis program was determined as well as the blood biochemical data including glucose, sodium, potassium, calcium, urea, and creatinine levels. Results. Totally 43 eyes of 43 patients (20 females and 23 males) with a mean age of 53.98 +/- 18.06 years were included in the study. Tear osmolarity of patients was statistically significantly decreased after hemodialysis (314.06 +/- 17.77 versus 301.88 +/- 15.22mOsm/L, p = 0.0001). In correlation analysis, pre-HD tear osmolarity was negatively correlated with pre-HD blood creatinine level (r = -0.366, p = 0.016). Post-HD tear osmolarity was statistically significantly correlated with the post-HD glucose levels (r = 0.305 p = 0.047). Tear osmolarity alteration by HD was negatively correlated with creatinine alteration, body weight alteration, and ultrafiltration (r = -0.426, p = 0.004; r = -0.365, p = 0.016; and r = -0.320, p = 0.036, resp.). There was no correlation between tear osmolarity and Kt/V and URR values. Conclusion. HD effectively decreases tear osmolarity to normal values and corrects the volume and composition of the ocular fluid transiently. Tear osmolarity alteration induced by HD is correlated with body weight changes, creatinine alterations, and ultrafiltration.
dc.identifier.citationTaşkapılı, M., Şerefoğlu Çabuk, K., Aydın, R., Atalay, K., Kırgız, A., Sit, D. ve Kayabaşı, H. (2015). The effects of hemodialysis on tear osmolarity. Journal of Ophthalmology. https://dx.doi.org/10.1155/2015/170361
dc.identifier.doi10.1155/2015/170361
dc.identifier.issn2090-004X
dc.identifier.issn2090-0058
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://dx.doi.org/10.1155/2015/170361
dc.identifier.urihttps://hdl.handle.net/20.500.12511/3236
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHindawi Publishing Corporation
dc.relation.ispartofJournal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHemodialysis
dc.subjectOsmolarity
dc.titleThe effects of hemodialysis on tear osmolarity
dc.typeArticle

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