The comparison of local tumor control after microwave ablation, surgical resection and combined treatment for colorectal liver metastases

Basit Öğe Kaydı
dc.authorid0000-0003-3468-7712
dc.authorid0000-0002-1240-7233
dc.authorid0000-0002-6745-0159
dc.authorid0000-0001-7934-7039
dc.authorid0000-0003-1941-8290
dc.authorid0000-0003-2342-073X
dc.authorid0000-0003-2357-5387
dc.contributor.authorGüngören, Fatma Zeynep
dc.contributor.authorErol, Cengiz
dc.contributor.authorBilici, Ahmet
dc.contributor.authorDayangaç, Murat
dc.contributor.authorŞeker, Mehmet
dc.contributor.authorÖlmez, Ömer Fatih
dc.contributor.authorYaprak, Onur
dc.contributor.authorYıldız, Özcan
dc.contributor.authorÖncel, Mustafa
dc.date.accessioned2022-05-06T07:39:31Z
dc.date.available2022-05-06T07:39:31Z
dc.date.issued2022
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı
dc.description.abstractAim. We aimed to compare the local therapeutic efficiency of microwave ablation (MWA), surgical resection, and combined treatment, assess the outcomes, and identify predictive factors for local treatment response in colorectal liver metastases (CLMs). Methods. From March 2013 to September 2019, a total of 54 patients with 302 CLMs were enrolled in this retrospective study. Eleven patients (20.4%) were treated with MWA, 9 patients (16.7%) with surgery, and 34 patients (63%) with the combined method. Univariate and multivariate analyses were performed to investigate overall survival (OS) and hepatic progression-free survival (HPFS) using the Cox proportional hazard regression model. The logistic regression analysis was used to identify the predictive factors for the local treatment response. Results. Total treatment response was achieved in 46.3% (n=25) of the patients. Local tumor progression was seen in 7.4% (n=4) of the patients, and the rate of intrahepatic distal recurrence was 46.3% (n=25). There were no significant differences in HPFS and OS between the three groups (p=0.56 and 0.90, respectively). Younger age (<60), smaller (<= 2 cm) or fewer (<= 3) liver metastases, and wild-type RAS were predictive for higher rates of local treatment response (OR 0.22, 95% CI 0.15-0.93, p=0.04; OR 1.12, 95% CI 0.54-2.12, p=0.029; OR 1.37, 95% CI 0.97-2.37, p=0.035; OR 0.23, 95% CI 0.10-0.85, p=0.028, respectively). Conclusions. The results of this study reveal that the use of MWA, alone or combined with resection, may achieve high local treatment response and similar survival rates compared to patients undergoing resection, suggesting that MWA could potentially be preferred over surgical procedures.
dc.identifier.citationGüngören, F. Z., Erol, C., Bilici, A., Dayangaç, M., Şeker, M., Ölmez, Ö. F. ... Öncel, M. (2022). The comparison of local tumor control after microwave ablation, surgical resection and combined treatment for colorectal liver metastases. Journal of Mind and Medical Sciences, 9(1), 125-132. https://doi.org/10.22543/7674.91.P125132
dc.identifier.doi10.22543/7674.91.P125132
dc.identifier.endpage132
dc.identifier.issn2392-7674
dc.identifier.issue1
dc.identifier.startpage125
dc.identifier.urihttps://doi.org/10.22543/7674.91.P125132
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9406
dc.identifier.volume9
dc.identifier.wos000786532500015en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorGüngören, Fatma Zeynep
dc.institutionauthorErol, Cengiz
dc.institutionauthorBilici, Ahmet
dc.institutionauthorDayangaç, Murat
dc.institutionauthorŞeker, Mehmet
dc.institutionauthorÖlmez, Ömer Fatih
dc.institutionauthorYaprak, Onur
dc.institutionauthorYıldız, Özcan
dc.institutionauthorÖncel, Mustafa
dc.language.isoen
dc.publisherValpoScholar-Valparaiso University
dc.relation.ispartofJournal of Mind and Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectColorectal Liver Metastases
dc.subjectMicrowave Ablation
dc.subjectSurgical Resection
dc.subjectCombined Treatment
dc.subjectLocal Tumor Control
dc.titleThe comparison of local tumor control after microwave ablation, surgical resection and combined treatment for colorectal liver metastases
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Gungoren-Fatma-2022.pdf
Boyut:
526.2 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu