Epidemiological features of primary glomerular disease in Turkey: A multicenter study by the Turkish Society of Nephrology Glomerular Diseases Working Group

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dc.contributor.authorTürkmen, Aydın
dc.contributor.authorŞumnu, Abdullah
dc.contributor.authorCebeci, Egemen
dc.contributor.authorYazıcı, Halil
dc.contributor.authorEren, Necmi
dc.contributor.authorSeyahi, Nurhan
dc.contributor.authorDilek, Kamil
dc.contributor.authorDede, Fatih
dc.contributor.authorDerici, Ülver
dc.contributor.authorÜnsal, Abdulkadir
dc.contributor.authorŞahin, Garip
dc.contributor.authorSipahioğlu, Murat
dc.contributor.authorGök, Mahmut
dc.contributor.authorTatar, Erhan
dc.contributor.authorDursun, Belda
dc.contributor.authorSipahi, Savaş
dc.contributor.authorYılmaz, Mürvet
dc.contributor.authorSüleymanlar, Gültekin
dc.contributor.authorUlu, Sena
dc.contributor.authorGüngör, Özkan
dc.contributor.authorKutlay, Sim
dc.contributor.authorBicik Bahçebaşı, Zerrin
dc.contributor.authorŞahin, İdris
dc.contributor.authorKurultak, İlhan
dc.contributor.authorTürkmen, Kültigin
dc.contributor.authorYılmaz, Zülfikar
dc.contributor.authorTuran Kazancıoğlu, Rümeyza
dc.contributor.authorÇavdar, Caner
dc.contributor.authorCandan, Ferhan
dc.contributor.authorAydın, Zeki
dc.contributor.authorOygar, Duriye Deren
dc.contributor.authorGül, Cuma Bülent
dc.contributor.authorArıcı, Mustafa
dc.contributor.authorPaydaş, Saime
dc.contributor.authorGüven Taymez, Dilek
dc.contributor.authorKüçük, Mehmet
dc.contributor.authorTrablus, Sinan
dc.contributor.authorTurgutalp, Kenan
dc.contributor.authorKoç, Leyla
dc.contributor.authorSezer, Siren
dc.contributor.authorDuranay, Murat
dc.contributor.authorBardak, Simge
dc.contributor.authorAltıntepe, Lütfullah
dc.contributor.authorArıkan, İzzet Hakkı
dc.contributor.authorAzak, Alper
dc.contributor.authorOdabaş, Ali Rıza
dc.contributor.authorManga Şahin, Gülizar
dc.contributor.authorÖztürk, Savaş
dc.date.accessioned2020-12-03T07:06:51Z
dc.date.available2020-12-03T07:06:51Z
dc.date.issued2020
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractBackground The largest data on the epidemiology of primary glomerular diseases (PGDs) are obtained from the databases of countries or centers. Here, we present the extended results of the Primary Glomerular Diseases Study of the Turkish Society of Nephrology Glomerular Diseases (TSN-GOLD) Working Group. Methods Data of patients who underwent renal biopsy and received the diagnosis of PGD were recorded in the database prepared for the study. A total of 4399 patients from 47 centers were evaluated between May 2009 and May 2019. The data obtained at the time of kidney biopsy were analyzed. After the exclusion of patients without light microscopy and immunofluorescence microscopy findings, a total of 3875 patients were included in the study. Results The mean age was 41.5 +/- 14.9 years. 1690 patients were female (43.6%) and 2185 (56.3%) were male. Nephrotic syndrome was the most common biopsy indication (51.7%). This was followed by asymptomatic urinary abnormalities (18.3%) and nephritic syndrome (17.8%). The most common PGD was IgA nephropathy (25.7%) followed by membranous nephropathy (25.6%) and focal segmental glomerulosclerosis (21.9%). The mean total number of glomeruli per biopsy was 17 +/- 10. The mean baseline systolic blood pressure was 130 +/- 20 mmHg and diastolic blood pressure was 81 +/- 12 mmHg. The median proteinuria, serum creatinine, estimated GFR, and mean albumin values were 3300 (IQR: 1467-6307) mg/day, 1.0 (IQR: 0.7-1.6) mg/dL, 82.9 (IQR: 47.0-113.0) mL/min and 3.2 +/- 0.9 g/dL, respectively. Conclusions The distribution of PGDs in Turkey has become similar to that in other European countries. IgA nephropathy diagnosed via renal biopsy has become more prevalent compared to membranous nephropathy.
dc.description.sponsorshipTurkish Society of Nephrologyen_US
dc.identifier.citationTürkmen, A., Şumnu, A., Cebeci, E., Yazıcı, H., Eren, N., Seyahi, N. ... Öztürk, S. (2020). Epidemiological features of primary glomerular disease in Turkey: A multicenter study by the Turkish Society of Nephrology Glomerular Diseases Working Group. BMC Nephrology, 21(1). https://dx.doi.org/10.1186/s12882-020-02134-8
dc.identifier.doi10.1186/s12882-020-02134-8
dc.identifier.issn1471-2369
dc.identifier.issue1
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://dx.doi.org/10.1186/s12882-020-02134-8
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6073
dc.identifier.volume21
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBioMed Central Ltd
dc.relation.ispartofBMC Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 4.0 International*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectEpidemiology
dc.subjectGlomerulonephritis
dc.subjectKidney Biopsy
dc.subjectPrimary Glomerular Diseases
dc.subjectThe Turkish Society of Nephrology Glomerular Diseases (TSN-GOLD) Working Group
dc.subjectTurkish Society of Nephrology
dc.titleEpidemiological features of primary glomerular disease in Turkey: A multicenter study by the Turkish Society of Nephrology Glomerular Diseases Working Group
dc.typeArticle

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