The relationship between metabolic syndrome, its components, and dry eye: A cross-sectional study

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dc.authorid0000-0001-9829-7268
dc.authorid0000-0003-0668-3749
dc.authorid0000-0001-8954-5055
dc.authorid0000-0002-9815-1848
dc.authorid0000-0002-2563-2149
dc.authorid0000-0002-5079-4713
dc.authorid0000-0001-5335-3860
dc.contributor.authorKaraman Erdur, Sevil
dc.contributor.authorAydın, Rukiye
dc.contributor.authorÖzsütçü, Mustafa
dc.contributor.authorOlmuşçelik, Oktay
dc.contributor.authorEliaçık, Mustafa
dc.contributor.authorDemirci, Göktuğ
dc.contributor.authorKocabora, Mehmet Selim
dc.date.accessioned10.07.201910:49:13
dc.date.accessioned2019-07-10T19:51:41Z
dc.date.available10.07.201910:49:13
dc.date.available2019-07-10T19:51:41Z
dc.date.issued2017
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.descriptionWOS: 000407080800005
dc.descriptionPubMed ID: 28328296
dc.description.abstractPurpose: The aim of this study was to evaluate tear osmolarity and tear film function and ocular surface changes in patients with metabolic syndrome.Methods: 108 eyes of 64 patients with metabolic syndrome (group 1) and 110 eyes of 55 healthy individuals (group 2) were included in this cross-sectional study. All participants were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear film break-up time (TBUT), and tear osmolarity. Main outcome measures were Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear film break-up time (TBUT), and tear osmolarity values.Results: Tear osmolarity values and OSDI scores were significantly higher in group 1 (314.4 19.1 mOsm and 38.9 +/- 1.1, respectively) compared with group 2 (295 +/- 14.3 mOsm and 18.69 +/- 17.2, respectively) (p = 0.01 for both). The Schirmer test values and TBUT in group 1 (10 +/- 3.7 mm and 14.8 +/- 3.6 sec, respectively) were significantly lower compared with group 2 (16.8 +/- 2.6 mm and 18.1 +/- 0.5 sec, respectively) (p < 0.001 for both). There was significant correlation between tear osmolarity versus waist circumference and fasting blood glucose in the study group (r = 0.364, p = 0.04; and r = 0.542, p 0.001, respectively).Conclusions: This study showed that metabolic syndrome can influence tear osmolarity and tear film function. Patients with metabolic syndrome showed tear hyperosmolarity and tear film dysfunction.
dc.identifier.citationKaraman Erdur, S., Aydın, R., Özsütçü, M., Olmuşçelik, O., Eliaçık, M., Demirci, G. ve Kocabora, M. S. (2017). The relationship between metabolic syndrome, its components, and dry eye: A cross-sectional study. Current Eye Research, 42(8), 1115-1117. https://dx.doi.org/10.1080/02713683.2017.1280511
dc.identifier.doi10.1080/02713683.2017.1280511
dc.identifier.endpage1117
dc.identifier.issn0271-3683
dc.identifier.issn1460-2202
dc.identifier.issue8
dc.identifier.scopusqualityQ2
dc.identifier.startpage1115
dc.identifier.urihttps://dx.doi.org/10.1080/02713683.2017.1280511
dc.identifier.urihttps://hdl.handle.net/20.500.12511/2264
dc.identifier.volume42
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTayor & Francis Inc
dc.relation.ispartofCurrent Eye Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDry Eye
dc.subjectMetabolic Syndrome
dc.subjectSchirmer Test
dc.subjectTear Osmolarity
dc.subjectTear Film
dc.titleThe relationship between metabolic syndrome, its components, and dry eye: A cross-sectional study
dc.typeArticle

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