Risk factors in addition to short and long-term outcomes with thin catheter surfactant administration failure in preterm infants: a retrospective analysis
| dc.contributor.author | Kanmaz Kutman, Hayriye Gözde | |
| dc.contributor.author | Siyah Bilgin, Betül | |
| dc.contributor.author | Büyüktiryaki, Mehmet | |
| dc.contributor.author | Kadıoğlu Şimşek, Gülsüm | |
| dc.contributor.author | Üstünyurt, Zeynep | |
| dc.contributor.author | Canpolat, Fuat Emre | |
| dc.date.accessioned | 2026-01-29T11:09:50Z | |
| dc.date.available | 2026-01-29T11:09:50Z | |
| dc.date.issued | 2025 | |
| dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | |
| dc.description.abstract | Objective: To evaluate the incidence of thin catheter surfactant administration (TCA) failure and compare short and long-term neonatal outcomes who failed TCA or did not. Design: Single-center retrospective cohort study. Infants between 25 and 30 weeks of gestational age with respiratory distress syndrome and receiving 200 mg/kg poractant alfa via thin catheter administration were included. TCA failure was defined as the need for early mechanical ventilation (< 72 h). Infants were divided into two groups those who failed TCA or those who did not. Results: The TCA failure rate was 24.6%. Initial oxygen requirement (0.39% vs. 0.36%) and the number of small for gestational age infants were significantly higher in the TCA failure group (15% vs. 7.9%). Infants who failed TCA had a higher pneumothorax (6.7% vs. 1.1%, p = 0.03), BPD (15% vs.5.5%, p = 0.02), late-onset sepsis (36.7% vs. 18%, p = 0.04), retinopathy of prematurity rates (11.7% vs. 3.3%, p = 0.02) and an increased duration of respiratory support. However, Bayley Scales of Infant Development II scores were comparable between groups at 18 and 26 months of corrected age. Conclusion: Infants who fail TCA are at increased risk for short-term complications despite favourable long-term neurodevelopmental outcomes. Identifying infants at risk of TCA failure may help early prevention of morbidities and individualise their management. | |
| dc.identifier.citation | Kanmaz Kutman, H. G., Siyah Bilgin, B., Büyüktiryaki, M., Kadıoğlu Şimşek, G., Üstünyurt, Z. ve Canpolat, F. E. (2025). Risk factors in addition to short and long-term outcomes with thin catheter surfactant administration failure in preterm infants: a retrospective analysis. Journal of Paediatrics and Child Health, 61(3), 451-456. http://dx.doi.org/10.1111/jpc.16777 | |
| dc.identifier.doi | 10.1111/jpc.16777 | |
| dc.identifier.endpage | 456 | |
| dc.identifier.issn | 1034-4810 | |
| dc.identifier.issn | 1440-1754 | |
| dc.identifier.issue | 3 | |
| dc.identifier.pmid | 39800857 | |
| dc.identifier.scopus | 2-s2.0-85214662333 | |
| dc.identifier.scopusquality | Q2 | |
| dc.identifier.startpage | 451 | |
| dc.identifier.uri | http://dx.doi.org/10.1111/jpc.16777 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12511/13392 | |
| dc.identifier.volume | 61 | |
| dc.identifier.wos | WOS:001396447800001 | |
| dc.identifier.wosquality | Q3 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.institutionauthor | Büyüktiryaki, Mehmet | |
| dc.institutionauthorid | 0000-0001-8937-4671 | |
| dc.language.iso | en | |
| dc.relation.ispartof | Journal of Paediatrics and Child Health | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Biological Products | |
| dc.subject | Infant | |
| dc.subject | Newborn | |
| dc.subject | Premature | |
| dc.subject | Respiratory Distress Syndrome | |
| dc.subject | Risk Factor | |
| dc.subject | Treatment Failure | |
| dc.title | Risk factors in addition to short and long-term outcomes with thin catheter surfactant administration failure in preterm infants: a retrospective analysis | |
| dc.type | Article |
