Bölüm "İstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Endodonti Ana Bilim Dalı" seçeneğine göre listele
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Öğe A bibliometric analysis of current trends, hotspots, and future aspects of endodontic-periodontal lesions(Ariesdue (S.R.L.), 2023) Usta, Sıla Nur; Uğur Aydın, Zeliha; Gündoğar, MustafaAim: This study aims to examine the present findings, contemporary developments, and productivity of endodontic-periodontal (endo-perio) lesions based on the top 50 most-cited articles between 1990 and 2022. Methodology: An electronic search was carried out in the " Clarivate Analytics Web of Science, All Databases". After ranking the articles in descending order based on their citation counts, the first 50 relevant articles were selected. Parameters such as citation density, publication year, journal, country, institution, author, study design, evidence level, and keywords were analyzed. Spearman's correlation was used to determine associations between the number of citations and citation density. Results: There was a significant positive correlation between citation number and the age of publication (p<0.05). Articles were mostly published between 2011 and 2022. The Journal of Endodontics had the largest number of publications. The United States and The University of Southern California made the highest contribution. The majority of the articles were case reports. Ilan Rotstein, Se-Lim Oh, and Maryam Pourhajibagher were the most frequent first authors. Studies were frequently designed as case reports with evidence level V. "Endo-perio lesions" followed by "guided tissue regeneration" were mostly-used keywords. Conclusion: Regenerative procedures along with endodontic treatments have been utilized in the last decade to manage endo-perio lesions due to the developments in materials and techniques. Case reports could guide dental practitioners by demonstrating updated information in this field.Öğe A clinical study on single-visit root canal retreatments on consecutive 173 patients: Frequency of periapical complications and clinical success rate(Springer, 2017) Eyüboğlu, Tan Fırat; Olcay, Kezban; Özcan, MutluThis study assessed the outcome measures of single-visit root canal retreatments and frequency of periapical complications considering preoperative, intraoperative and postoperative factors. Between November 2011 and December 2012, in 173 patients, a total of 234 endodontically treated teeth were retreated in a single appointment by one experienced endodontist. Five teeth were extracted and 119 teeth were lost to follow-up yielding to 110 teeth (47 %) to be examined by two calibrated examiners for the outcome of healing (periapical index score-PAI <= 2; no signs or symptoms) or non-healing (presence of apical periodontitis-PAI > 2; signs or symptoms). Preoperative, intraoperative and postoperative factors were evaluated for their association with the outcome. Data were analysed using Fisher's exact and Fisher-Freeman Halton tests for bivariate analysis to identify potential outcome predictors. Logistic regression models were used for multivariate analysis to determine significant outcome predictors. Mean observation time was 29 months. Follow-up assessment revealed 100 teeth (90.9 %) as healed and 10 teeth (9.1 %) non-healed. Age, gender, tooth type and preoperative (pain, periodontal defects, root filling density and length), intraoperative (sealer extrusion) and postoperative (type of coronal restorations) factors did not significantly affect the outcome (p > 0.05). Preoperative periradicular lesions with diameters less than 5 mm presented significantly better outcome than larger lesions (p < 0.05; odds ratio (OD) 6; 95 % CI 1.45-24.85). Logistic regression model showed an increased risk of non-healing for the parameter of preoperative periradicular lesions with diameters larger than 5 mm (OD 6.42; 95 % CI 1.51-27.27). Single-appointment root canal retreatments presented a favourable success rate. Only preoperative lesion size had a significant effect on the outcome where the lesions smaller than 5 mm performed significantly better healing. Single-appointment root canal retreatments could be considered as a viable treatment option for orthograde retreatment cases with periradicular lesion size smaller than 5 mm.Öğe Adhesion of veneering composite to metal-free CAD/CAM materials: Effect of surface conditioning and adhesive resin type(Taylor and Francis Ltd., 2023) Önügören, Nazik İrem; Demirci, Fatih; Tatar, Numan; Eyüboğlu, Tan Fırat; Özcan, MutluObjectivesThis study aimed to investigate the adhesion of veneering composite to metal-free computer-aided design/computer-aided manufacturing (CAD/CAM) materials with different compositions after surface conditioning and application of adhesive resins.Materials and MethodsA total of one hundred and sixty specimens were divided into four groups (n = 40) manufactured either from polyetheretherketone (PEEK; KERAstar PEEK), polyetherketoneketone (PEKK; Pekkton), fiber-reinforced composite (FRC; Trinia), or high-impact polymer composite (COMP; Bredent HIPC) CAD/CAM discs. Each group was then randomly subdivided into four different subgroups of adhesive systems (n = 10) as Visiolink (Bredent), Single Bond Universal (3M), G-Premio BOND (GC), and OptiBond Universal (Kerr). The shear bond strength (SBS) of each specimen with veneering composite material was tested with a universal testing machine following thermocycle aging (5000 times). The modes of failure resulting from the tests were determined with scanning electron microscope (SEM), dispersive spectroscopy (EDS), and analytical imaging. The data were statistically analyzed with two-way ANOVA and Bonferroni post hoc tests (alpha = 0.05).ResultsThe highest SBS values among all groups were found for the COMP material (20.28 +/- 2.08 MPa) with OptiBond Universal adhesive, while the lowest for the PEEK material (10.33 +/- 2.47 MPa) with G-Premio BOND. The most common failure mode for the PEEK and PEKK specimens was adhesive failure, for the FRC and COMP groups mixed failures were common.ConclusionsBond strength values of at least 10 MPa were achieved for all tested between metal-free CAD/CAM materials and adhesive resin application.Öğe Antibacterial efficacy of copper-added chitosan nanoparticles: A confocal laser scanning microscopy analysis(Springer, 2021) Keskin, N. Bora; Uğur Aydın, Zeliha; Uslu, Gülşah; Özyürek, Taha; Erdönmez, Demet; Gündoğar, MustafaThe aim of this study was to evaluate the antibacterial efficacy of copper added chitosan nanoparticles (CU-CNPs) as an irrigation solution with different irrigants in terms of eliminating Enterococcus Faecalis (E. faecalis) from the root canals. Fifty mandibular premolar teeth were prepared and infected with E. faecalis for 21 days. After the incubation period, samples were randomly divided into a control group irrigated with distilled water and 4 experimental groups (n = 10) irrigated with as follows, %6 NaOCl, %6 NaOCl + %9 editronate (HEBP), Chitosan nanoparticles (CNPs), and CU-CNPs. To calculate the proportion of dead E. faecalis cell volume, stained using LIVE/DEAD BacLight Bacterial Viability Kit and were scanned using confocal laser scanning microscope (CLSM). All the irrigation solutions significantly (P < .05) killed the bacteria in the canal, except for the control group. CU-CNPs solution killed the highest (P < .05) number of bacteria compared with the other experimental groups. No significant difference was found between CNPs, NaOCl + HEBP, and NaOCl in terms of antibacterial activity. CU-CNPs solution was exhibited higher antibacterial efficacy against E. faecalis.Öğe Apically extruded debris during root canal instrumentation with reciproc blue, hyflex edm, and xp-endo shaper nickel-titanium files(Elsevier Science Inc, 2018) Uslu, Gülşah; Özyürek, Taha; Yılmaz, Koray; Gündoğar, Mustafa; Plotino, GianlucaIntroduction: The purpose of this study was to investigate the amount of apically extruded debris by Reciproc Blue (REC Blue; VDW, Munich, Germany), HyFlex EDM (HEDM; Coltene/Whaledent, Altstatten, Switzerland), and XP-endo Shaper (XPS; FKG Dentaire SA, La Chaux-de-Fonds, Switzerland) files during root canal preparation at body temperature. Methods: Sixty extracted single-rooted mandibular premolar human teeth were randomly assigned to 3 groups (n = 20). The canals were instrumented using 1 of the following instruments: REC Blue, HEDM, or XPS. Apically extruded debris during instrumentation was collected into pre-weighed Eppendorf tubes. All the procedures were performed at 35 degrees C. The amount of extruded debris was calculated by subtracting the weight value of the tooth-free apparatus from the postpreparation weight value. The data were analyzed using the KruskalWallis test at a 5% significance level. Results: All the instruments tested caused extrusion of some debris from the apical foramen. XPS extruded significantly less debris from the apex than REC Blue (P <.05). The difference among the HEDM group and the other groups was not significant (P> .05). Conclusions: Within the limitations of this in vitro study, the amount of apically extruded debris registered for the different files tested was REC Blue> HEDM> XPS, with a statistical difference only between XPS and REC Blue.Öğe Are dentin posts biomechanically intensive?: A laboratory and FEA study(Taylor & Francis, 2014) Belli, Sema; Çelik, Kezban; Akbulut, Makbule Bilge; Güneşer, Mehmet Burak; Eraslan, Oğuz; Eskitaşcıoğlu, GürcanThe goal of this laboratory and finite elemental stress analysis (FEA) study was to compare fracture strength of dentin post (DP) with stainless steel and glass fiber posts. Single-rooted teeth were decoronated and restored with ParaPost (PP), i-TFC (TFC), and DPs (n=10). Resin cores were created and loaded until failure (1.0mm/min). The data were analyzed (ANOVA, Tukey, Chi-Square tests). Three-dimensional FEA models of the posts were created and the stress distributions were calculated using Solid Works/Cosmos works structural analysis program. A significant difference was found among the groups (p<0.001). TFC group showed the highest and the DP group showed the lowest fracture resistance (p<0.001). PP created more stress at the root dentin and inside the post. Restoration of roots with glass fiber and DPs may reduce stresses within the core material and the remaining root. However, a fracture-resistant restoration cannot be achieved by using a DP.Öğe Asemptomatik dişlerde tek seansta ve farklı medikamentler kullanılarak çok seansta yapılan yeniden kanal tedavisi uygulamalarında oluşan postoperatif ağrının karşılaştırılarak değerlendirilmesi(İstanbul Medipol Üniversitesi Diş Hekimliği Fakültesi, 2017) Erdem Hepşenoğlu, Yelda; Eyüboğlu, Tan FıratKanal tedavisi, kök kanalı içerisindeki enfekte dokunun uzaklaştırılarak geriye kalan yapının orjinal forma uygun genişletilip, temizlenerek doldurulmasını içeren bir tedavi şeklidir. Eskiden birkaç seansta tamamlanan bu tedavi tekniği, yeni çıkan aletler ve malzemeler ile tek seansta güvenli bir şekilde tamamlanabilmektedir. Tek seansta yapılan uygulamalar, birden fazla seansta uygulanan kanal tedavilerine göre daha avantajlıdır. Yeniden kanal tedavisi uygulaması daha önce kanal tedavisi yapılmış ancak başarısız olmuş dişlerde kanal tedavisinin yeniden uygulanmasını öngören bir tedavi tekniğidir. Postoperatif ağrı, seans sayısı kadar, tedavi öncesinde ve tedavi sırasında karşılaşılan faktörlerle de ilişkilendirilmektedir. Tek veya c?ok seans yeniden kanal tedavisi uygulamalarından sonra hastalarda farklı du?zeylerde ag?rı s?ikayetleri olmaktadır. Bu ağrı genelde artık pulpa dokusu ve periodontal dokuların iltihabi reaksiyonu ile meydana gelmektedir. Yeniden kanal tedavisi protokolünün, tek seansta güvenli ve verimli bir şekilde yapılabilmesi klinik endodonti uygulamalarında zaman kazanımı ve masraf açısından daha verimli bir aşamaya geçilmesini sağlayacaktır. Ayrıca çok seansta yapılan kök kanal tedavilerinde, kök kanalının komplike anatomik yapısı nedeniyle seans arasında uygulanan kanal içi medikamentlerin dentin kanalcıklarında, istmuslarda ve lateral kanallardaki mikroorganizmalara ulaşamaması veya bazı mikroorganizmalara karşı etkisiz kalması söz konusu olabilmektedir. Ek olarak geçici dolgu bulunan kronun kırılmaya müsait yapısı ve Ca(OH)2 gibi bazı kanal içi medikamentlerin kostik etkileri nedeniyle dentin direnci azaldığı için kök kanal tedavisi esnasında veya sonrasında kırık riski ortaya çıkmaktadır. Bu nedenle bu çalışmada asemptomatik 2 dişlerde tek seansta ve farklı medikamentler kullanılarak çok seansta yapılan yeniden kanal tedavisi uygulamalarında oluşan postoperatif ağrının karşılaştırılarak değerlendirilmesi amaçlanmıştır.Öğe Assessment of the canal anatomy of the premolar teeth in a selected Turkish population: A cone-beam computed tomography study(BMC, 2023) Erkan, Erhan; Olcay, Keziban; Eyüboğlu, Tan Fırat; Şener, Elif; Gündoğar, MustafaBackgroundTeeth may have additional roots and a different number of root canals. Overlooked root canals may cause endodontic failure. The aim of this study was to investigate the prevalence of root canals and the number of roots of premolars in a selected Turkish population.Materials and methodsA total of 2,570 teeth from 1,438 patients were evaluated. The cone-beam computed tomography scans of 1,055 maxillary and 1,515 mandibular premolars were examined.ResultsType IV root canal morphology was observed most frequently in maxillary first premolars (77%), and the rates of single and double channel formations were very similar (51% and 49%, respectively). Of the second maxillary premolars, 57.4% had Type I morphology, and 89.9% of the teeth were single-rooted, while 68.6% had a single root canal. The most common formation was Type I (85%) among mandibular first premolars, and a single root was observed in 95.6% of these teeth. In addition, 87% of the mandibular first premolars had a single root canal. The second mandibular premolars mostly had Type I (95.4%) formation, and 99.3% of the teeth were single-rooted, while 96.9% had a single root canal.ConclusionAccording to our findings, 51% of maxillary first premolars had a single root, 79.4% had two root canals, and 77% had Type IV (77%) formation. Maxillary second premolars mostly had Type I formation. In addition, a single root and single root canal formation were most common. Mandibular first premolars generally had a single root and single root canal formation, but 13% had two root canals, and 6.4% had Type V formation. More than 95% of mandibular second premolars had Type I formation.Öğe Association between C-reactive protein, neutrophil to lymphocyte ratio and the burden of apical periodontitis: A case-control study(Taylor & Francis Ltd, 2019) Şirin, Dursun Ali; Özçelik, Furkan; Uzun, Canan; Erşahan, Şeyda; Yeşilbaş, SonerObjective: Endodontic originated chronic apical periodontitis (AP) is an inflammatory disease of periapical tissue. High-sensitivity C-reactive protein (hsCRP) as an inflammatory marker and hemogram indexes provide valuable information to clinicians for diagnosis, screening and follow-up of various diseases. The aim of this study was to investigate AP in terms of its association with hemogram indices and hsCRP levels. Material and methods: Study includes 104 patients with AP and 40 participants as the control group. 160 teeth were diagnosed as AP through digital radiographic images and scored with respect to Periapical Index (PAI) scoring. Afterwards, patients were categorized into 3 grades in accordance with both the number and the severity of AP. AP grade 0 was considered for the control group with regard to a new scoring system. Patients with only one tooth involved with AP with a PAI score of 3 or 4 were categorized as an AP Grade 1, when a patient had more than one tooth with a PAI score of 3 or 4 he was classified as an AP Grade 2 and a patient with at least one tooth scored as a PAI 5 was rated as an AP Grade 3. Hemograms and hsCRP levels were measured for each individual to establish a correlation with inflammatory markers. Results: The neutrophil/lymphocyte ratio (NLR) levels of patients with AP Grade 3 were significantly higher than all other AP grades (p<.05). hsCRP levels in patients with an AP Grade 2 and 3 were higher than both AP Grade 0 and 1 (p<.05). Conclusions: hsCRP levels of patients were reliable predictive indicators for AP severity in correlation with the new proposed scoring system for AP.Öğe Association between temporomandibular disorders and irritable bowel syndrome: a scoping review(2024) Saczuk, Klara; Roszuk, Sylwia; Wirkijowska, Malgorzata; Fabisiak, Adam; Eyüboğlu, Tan Fırat; Özcan, Mutlu; Lukomska Szymanska, MonikaTemporomandibular disorders (TMDs) encompass various clinical conditions associated with the temporomandibular joint (TMJ) and the masticatory muscles. TMD symptoms include pain in the orofacial region, restricted or altered mandibular movement, and sounds associated with the temporomandibular joint (TMJ). This condition adversely affects quality of life, social functioning, and daily activities, and may also contribute to widespread pain syndromes and comorbidities, including irritable bowel syndrome (IBS). IBS is a common chronic functional disorder of the lower gastrointestinal tract, characterized by recurrent abdominal pain associated with impaired bowel symptoms. Previous studies indicate an association between TMD and IBS. This scoping review examined the correlation between TMD and IBS concerning their pathology, frequency, and severity, and the potential similarities in how the nervous and endocrine systems influence them. PubMed, SCOPUS, Web of Science, and Google Scholar search engines were utilized to identify suitable studies for this article. Following the application of selection criteria, a total of 58 clinical papers met the eligibility requirements for inclusion in the systematic review. Research showed that both conditions significantly enhance the development of one another and have mutual comorbidities. Both ailments were proven to modify central nervous system processing, leading to high comorbidity in patients. Combining dental and gastroenterological treatments, including a simultaneous therapeutic approach, can significantly enhance patients’ quality of life, but further research is needed for a holistic approach.Öğe Clinical outcome of non-surgical root canal treatment using different sealers and techniques of obturation in 237 patients: A retrospective study(2024) Radwanski, Mateusz; Pietrzycka, Krystyna; Eyüboğlu, Tan Fırat; Özcan, Mutlu; Lukomska Szymanska, MonikaObjectives: The aim of this retrospective study was to compare the clinical results of two root canal sealers and three obturation techniques used for non-surgical root canal treatment. Materials and methods: A total of two hundred eighty-three root canal treated teeth in two hundred thirty-seven patients with minimum a 6-month follow-up was included for this study. The canals were filled with three different modes: 1) cold lateral condensation (CLC) and AH Plus Sealer; 2) continuous wave condensation technique (CWC) and AH Plus Sealer, and 3) sealer-based obturation technique (SBO) and AH Plus Bioceramic Sealer. The treatment outcome was analysed based on clinical signs and symptoms, and periapical radiograph (periapical index, PAI). Results: There were no significant differences in treatment outcome between various sealers and filling techniques applied. The sealer extrusion was found most frequently in the CWC group (60.67%), followed by SBO (59.21%) and CLC (21.19%) with statistically significant differences (p <.05). The initial diagnosis, previous treatment and sealer extrusion (p <.05) were prognostic factors that affected treatment outcome. Conclusions: Based on the findings of this study, neither the sealer type nor the filling technique affected the treatment success while preoperative diagnosis, previous treatment and sealer extrusion had significant effect on the outcome. Clinical relevance: A bioceramic sealant applied along with the single-cone technique might be considered as an alternative method in root canal obturation.Öğe Clinical outcomes of non-surgical multiple-visit root canal retreatment: a retrospective cohort study(Springer, 2019) Olcay, Keziban; Eyüboğlu, Tan Fırat; Özcan, MuratThis study aimed to investigate the effects of several clinical factors on the success and survival rates of multiple-visit non-surgical root canal (NSRC) retreatment. Failed endodontically treated 236 teeth in 161 patients (18-72 years, 48% males; and 52% females) were retreated between March 2014 and December 2015 and were enrolled in this study. Two calibrated examiners evaluated the preoperative, intraoperative, and postoperative outcomes using the periapical index (PAI) scores. The teeth were classified as healed (healthy apical tissues, PAI <= 2, no signs or symptoms), healing (no signs and symptoms, PAI > 2 but reduced from the initial PAI score), and not-healed (presence of apical periodontitis, signs and/or symptoms, PAI > 2). The teeth scored as healed and healing was considered to be successful, while the not-healed ones were considered as failures. Of the 236 teeth, 135 (57.3%) in 103 patients (63.9%) were lost to follow-up, yielding to follow-up of 101 teeth (42.7%) in 58 patients (36%). Three teeth were extracted yielding to an overall success rate of 85.1%, at a mean observation time of 33.8 months. The teeth with periapical lesions < 5 mm had an 88.6% success rate, while those >= 5 mm had an 80% success rate (P > 0.05). While, age, gender, preoperative, intraoperative, and postoperative factors did not significantly affect the outcomes (P > 0.05), tooth type significantly affected the success rate (P < 0.05). The most frequently failed teeth were the mandibular first molars (P < 0.05). Based on these results, the multiple-visit NSRC retreatment exhibited a favorable success rate and could be offered for the endodontically failed teeth.Öğe Clinical survival of indirect, posterior fiber-reinforced composite fixed dental prosthesis up to 15 years of prospective clinical follow up(2024) Barabanti, Nicola; Özcan, Mutlu; Eyüboğlu, Tan Fırat; Cerrutti, AntonioThis prospective clinical study evaluated the survival of indirect, posterior fiber-re-inforced composite fixed dental prosthesis (FRC FDP). Between June-1999 and June-2000, 58 patients received 65 FCR FDPs made of unidirectional E-glass fibers (Vectris) veneered with resin composite (Signum) that were adhesively cemented (Variolink II). The evaluation protocol involved technical (chipping, debonding or fracture of tooth/res-toration) and biological failures (caries, endodontic complications). Altogether, 6 technical failures were observed after a mean observation time of 180 months (survival rate: 89.2%, Kaplan-Meier) in the form of fractures (n=2) and partial debondings (n=4). All defective restorations were repaired or recemented. Secondary caries occurred in one patient after 11 years. The 3-unit posterior FRC FDPs showed good clinical survival rate up to 15 years of clinical function. Limited numbers of experienced failures were due to mainly debonding followed by fracture of the veneering composite.g composite.Öğe Comparative evaluation of postoperative pain intensity after single-visit and multiple-visit retreatment cases: A prospective randomized clinical trial(Universidade Estadual Paulista, Institute of Science and Technology of Sao Jose Dos Campos, 2018) Uyan, Hatice Miray; Olcay, Keziban; Özcan, MutluObjectives: This study was designed to evaluate postoperative pain after endodontic retreatment. Material and Methods: Asymptomatic, multirooted molar & premolar teeth requiring retreatment with 2–5 mm periapical lesions were included Seventy-eight teeth were randomly placed in four groups (n=20): single-visit (control, group 1), Ledermix (group 2), metronidazole, ciprofloxacin, minocycline mixture (group 3), calcium hydroxide (group 4). The postoperative pain was recorded using a VAS at 6, 12, 24, and 48 h after retreatment. Statistical evaluation was performed using Two-Way Repeated Measures ANOVA and Tukey test. Results: Mild pain occurred in 67.5%, moderate in 30%, and flare-ups in 2.5%, and there was a significant difference between the groups (p<0.01). Significantly lower postoperative pain was observed in TAP and CaOH2 groups (p<0.05). In the 6, 12, and 24 h intervals, there was a significant difference in the pain levels (p<0.05). Conclusion: TAP and CaOH2 are effective for reducing postoperative pain after retreatment.Öğe Comparison of cyclic fatigue resistance and bending properties of two reciprocating nickel-titanium glide path files(Wiley, 2018) Özyürek, Taha; Uslu, Gülşah; Gündoğar, Mustafa; Yılmaz, Koray; Grande, Nicola Maria; Plotino, GianlucaAimTo compare the cyclic fatigue resistance and bending properties of R-Pilot and WaveOne Gold (WOG) Glider files, at intracanal temperature (35 degrees C). MethodologyForty R-Pilot and 40 WOG Glider files were subjected to a cyclic fatigue resistance test (n=20), calculating the time to fracture (TTF) in an artificial stainless steel canal. The length of the fractured file tips (FL) was also measured. The fracture surface of fragments was examined with a scanning electron microscope, and the cross-sectional area of the fractured surfaces was measured. Flexibility of the tested files (n=20) was determined using 45 degrees bending test. Data were analysed statistically using the Mann-Whitney U-test at 5% significance level. ResultsTime to fracture was significantly higher in the R-Pilot group compared to the WOG Glider (P<0.05). There was no significant difference between groups for fracture length. The bending resistance of R-Pilot files was significantly greater than WOG Glider files (P<0.05). ConclusionsA significant greater cyclic fatigue resistance was observed for R-Pilot files compared to WOG Glider instruments, although the bending resistance of WOG Glider files was lower.Öğe Comparison of electronic apex locator and simultaneous working length detection methods with radiological method in terms of postoperative pain(2024) Güzel, Emine; Uyan, Miray; Erşahan, Şeyda; Gündoğar, Mustafa; Özçelik, FatihBackground: Precise knowledge of the apical construction, which determines the end of the area for canal preparation and filling, is essential for the success of root canal treatment and the management of postoperative pain. For this purpose, devices based on various methods that determine the working length (WL) are used. However, it is still controversial which method provides the most accurate measurements. Aim: To investigate the compatibility of the electronic apex locator (EWL) and simultaneous working length determination (SWL) methods in single-root teeth in comparison with the radiographic working length determination (RWL) method and to determine which one produced more effective results in terms of postoperative pain. Materials & methods: One hundred patients scheduled for root canal treatment (RCT) were randomly assigned to one of the three groups according to the working length measurement method (EWL, SWL or RWL). After WL determination with assigned method, root canals were prepared and then obturated. Age, gender, simplified oral hygiene index (OHI-S), oral and dental examinations and Visual Analogue Scale (VAS) results of all participants were recorded. The incidence and intensity of postoperative pain were rated on a Visual Analogue Scale (VAS) by patients 6, 12, 24, 48 h and 7 days after RCT. The number of analgesic tablets (400 mg Ibuprofen) taken by patients was also recorded. Data were analyzed using the chi-square, One- way ANOVA and Kruskal-Wallis tests. Bland-Altman and Passing-Bablock regression analysis were used as method comparison techniques. Results: It was determined that the number of patients receiving analgesia and the total number of analgesia doses were higher in EWL and RWL groups compared to SWL group (p < 0.0001). When the WL values at which the treatment was applied were compared in the patient groups; WL values of EWL group were statistically lower than SWL group (p < 0.01). While there was no difference between the preoperative VAS scores of the groups (p = 0.7590), the postoperative 6th and 12th hour VAS scores of SWL group were lower than those of EWL and RWL groups (p = 0.005 and p = 0.0002, respectively). Again, the VAS scores of SWL group at the 24th and 48th postoperative hours were lower than those of RWL group (p < 0.05). According to the Bland-Altman and Passing-Bablock regression analysis results, although there was no statistically significant difference between the EWL and SWL methods (p = 0.471), the bias value of -0.1190 was well below the acceptable total error (0.1648). Additionally, a strong relationship was found between EWL and SWL methods (r = 0.9698, r2 = 0.9406, p < 0.001). Therefore, statistically these two methods were considered compatible with each other. It was determined that there was a statistically significant bias (0.340, p < 0.0001) between the RWL and SWL methods, exceeding the total error. Conclusions: As a result, it was determined that the SWL method, which is used to determine working length for the success of endodontic treatment, can be used as an alternative to the EWL method thus producing more effective results in the management of postoperative pain. However, in addition to the method used, the technology of the device developed for this method should not be ignored. Clinical relevance: Precise knowledge of the apical construction, which determines the end of the area for canal preparation and filling, is essential for the success of root canal treatment and the management of postoperative pain. For this purpose, devices based on various methods that determine the working length are used. However, it is still controversial which method provides the most accurate measurements. This study found that the simultaneous working length determination method can be used as an alternative to the electronic working length determination method and produces more effective results in the management of postoperative pain. Another important outcome of this study is that the Total Allowable Error (TEa) for the electronic apex locator method, which is accepted as the reference, has been calculated for the first time. Other methods have been evaluated according to this reference method. This is a first in literature.Öğe Comparison of four different electronic pain rating scales in patients with symptomatic tooth(Ege Üniversitesi Diş Hekimliği Fakültesi, 2020) Eyüboğlu, Tan FıratIntroduction: The study aimed was to assess correlation and evaluate the agreement level between four different electronic pain rating scales in patients with symptomatic teeth.Methods: 50 patients with symptomatic teeth who consented were enrolled for this study. Patients’ age, sex, tooth type was recorded. Patients were then asked to mark their pain intensity on four pain rating scales; Visual Analogue Scale (VAS), Color Analogue Scale (CAS), Numerical Rating Scale (NRS) and Faces Rating Scale (FRS) before root canal treatment via an electronic pain rating program. All scores were then subjected to statistical analysis to assess correlation and agreement level in pain interpretation.Results: A positive correlation was found between all pain rating scales (p<0.001). The highest correlation was observed between CAS and NRS scores (r=0.930, p<0.001). The highest level of agreement in pain interpretation was observed between CAS and NRS (0.685, p <0.001) while, the lowest was between CAS and FRS (0.384, p<0.001).Discussion and Conclusion: All rating scales presented a strong positive correlation whit a moderate level of agreement between scales indicating subjectivity of pain rating procedure.Öğe Comparison of four electronic apex locators in detecting working length: An ex vivo study(Jaypee Brothers Medical Publishers (P) Ltd, 2018) Yolagiden, Mehmet; Erşahan, Şeyda; Suyun, Gökhan; Bilgeç, Ertürk; Aydın, CumhurAim: To compare the accuracy of four different electronic apex locators (EALs) in detecting a position 0.5 mm short of the major foramen. Materials and methods: The actual working length of thirty-five extracted human teeth was determined visually as 0.5 mm short of the apical foramen. After actual working length measurements, electronic working length was measured with four different EALs (Apex Pointer+, Raypex 5, Apex ID, and Raypex 6). Measurements were repeated three times by different operators. The data were analyzed using the intraclass correlation coefficient (ICC), the repeated measure analysis of variance (rANOVA) and Bonferroni post hoc tests. The significance level was set at p = 0.05. Results: The mean differences between electronic and actual working length were-0.305 mm, 0.098 mm, 0.037, and 0.144 mm for the Apex Pointer+, the Raypex 5, the Apex ID, and the Raypex 6, respectively. Multiple paired comparisons (Bonferroni test) also showed the Apex Pointer+ is significantly different from the Raypex 5, Apex ID and Raypex 6 (p = 0.000, p = 0.001, and p = 0.001 respectively). Conclusion: All EALs showed an acceptable determination of the working length between the ranges of ± 0.5mm except for the Apex Pointer+ device, which had the lowest accuracy. Further studies may be beneficial especially to better evaluate the accuracy of the Apex Pointer+. Clinical significance: This article shows that Apex ID, which has only recently been introduced into the market, showed an acceptable determination of the working length. Its accuracy was similar to that of Raypex 5 and 6.Öğe Comparison of the cyclic fatigue resistance of VDW.ROTATE, TruNatomy, 2Shape, and HyFlex CM nickel-titanium rotary files at body temperature(Korean Academy of Conservative Dentistry, 2020) Gündoğar, Mustafa; Uslu, Gülşah; Özyürek, Taha; Plotino, GianlucaObjectives: This study aims to compare the cyclic fatigue resistance of VDW.ROTATE, TruNatomy, 2Shape, and HyFlex CM nickel-titanium (NiTi) rotary files at body temperature.Materials and methods: In total, 80 VDW.ROTATE (25/0.04), TruNatomy (26/0.04), 2Shape (25/0.04), and HyFlex CM (25/0.04) NiTi rotary files (n = 20 in each group) were subjected to static cyclic fatigue testing at body temperature (37°C) in stainless-steel artificial canals prepared according to the size and taper of the instruments until fracture occurred. The number of cycles to fracture (NCF) was calculated, and the lengths of the fractured fragments were measured. The data were statistically analyzed using a 1-way analysis of variance and post hoc Tamhane tests at the 5% significance level (p < 0.05).Results: There were significant differences in the cyclic fatigue resistance among the groups (p < 0.05), with the highest to lowest NCF values of the files as follows: VDW.ROTATE, HyFlex CM, 2Shape, and TruNatomy. There was no significant difference in the lengths of the fractured fragments among the groups. The scanning electron microscope images of the files revealed typical characteristics of fracture due to cyclic fatigue.Conclusions: The VDW.ROTATE files had the highest cyclic fatigue resistance, and the TruNatomy and 2Shape files had the lowest cyclic fatigue resistance in artificial canals at body temperature.Öğe Comparison of the effects of two different analgesics on bone regeneration during mandibular distraction osteogenesis(Lippincott Williams and Wilkins, 2019) Alakuş Sabuncuoğlu, Fidan; Erşahan, Şeyda; Amasyalı, Mihri; Avunduk, Mustafa CihatIntroduction: Mandibular distraction osteogenesis (DO) is frequently used in the management of bone defects and craniofacial deformities, with analgesics commonly administered to relieve acute postoperative pain. This experimental animal study investigated the effects of 2 analgesics, acetaminophen and acemetacin, on bone regeneration after DO. Materials and methods: This study was conducted with 14 mature male New Zealand rabbits (2.8-32 kg) randomized into 2 groups of 7. Mandibular osteotomies were performed under optimal operating conditions, and a custom-made distractor was applied to the mandible of each subject, with distraction initiated after a 5-day latency period at a rate of 1.0 mm/d (2 x 0.5 mm/d) for 10 days. Analgesics were administered via oral gavage during the latency period and for the first 5 days of the distraction period for 10 days in total, with group I receiving acetaminophen (200 mg/kg/d) and group II receiving acemetacin (5 mg/kg/d). Subjects were sacrificed and their mandibles dissected at the end of 4 weeks postoperatively. Bone mineral density (BMD) and bone mineral content (BMC) were measured using dual-energy X-ray absorptiometry (DEXA), and histomorphometric analysiswas performed to evaluate the quality of newly formed bone. Paired group comparisons of non-normally distributed numerical variables were made using the Mann-Whitney U test, with a P value of <0.05 considered statistically significant. Results: No significant differences in BMC and BMD values of intact bone, newly formed bone, or bone around the pin site were observed between the 2 groups. Histometric analysis also indicated acetaminophen and acemetacin to have similar effects on bone regeneration during distraction. Conclusion: Acemetacin may be an alternative to acetaminophen for treating pain associated with DO, given the similarities in the effects of the 2 analgesics on bone regeneration. However, this finding should be supported by further experimental and human studies.
