Bölüm "İstanbul Medipol Üniversitesi, Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Cerrahisi Ana Bilim Dalı" seçeneğine göre listele
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Öğe A city-wide survey of dental students' opinions on undergraduate oral surgery teaching(Wiley, 2020) Burdurlu, Muammer Çağrı; Cabbar, Fatih; Dağaşan, Volkan; Çukurova, Zeynep Gülen; Doğanay, Özge; Yalçın Ülker, Gül Merve; Atalay, Berkem; Gönül, Onur; Özçakır Tomruk, CeydaPurpose This study aimed to carry out a city-wide survey to evaluate undergraduate students' opinions on their oral surgery training by measuring their self-confidence.Materials and Methods A cross-sectional survey of 383 3rd year, 412 4th year and 363 5th year undergraduate dental students from six dental schools in Istanbul with a mean age of 22.73 +/- 1.55 was conducted towards the end of the academic year. A web link to the questionnaire was sent to the contact person at the participating dental schools. The questionnaires were anonymously evaluated. Descriptive statistics were calculated, and Chi-square tests were performed to examine the data. A P-value of In total, 1158 responses were returned, representing 67% of the overall students in the 2018-2019 academic year. The male respondents were significantly more self-confident than females in the general aspects of surgical skills. More than half of the respondents (53%) felt confident in oral surgery knowledge to undertake independent practice. Although 5th year respondents felt more confident in the general aspect of the questionnaire, their ability of differentiation of odontogenic and non-odontogenic pain was lower than their counterparts. The majority (86%) of the participants disagreed that the only knowledge required for oral surgery was that of tooth and jaw anatomy.Conclusion This survey revealed perceived confidence in tooth and retained root extraction. The male respondents were found to be more self-confident. There is a need for improvement in surgical skills, recognition of malignancies and differentiation of the origin of the pain.Öğe A large mass in the mandible of an eight year old child(2017) Gürler, Gökhan; Yılmaz, Serdar; Delilbaşı, Barış Çağrı; Tekkesin, Merva SolukFacial swellings in children may commonly arise from infection, jaw cysts or benign-malign tumors. Differential diagnosis should be handled considering onset of the symptoms, growth rate and child’s age. Fibro-osseous lesions are a group of lesions characterized by fibrosis and contain varying amounts of calcified tissue resembling bone, cement or both. Such lesions may cause enlargement and swelling in the jaws. Juvenile ossifying fibroma (JOF) is one of the fibro-osseous lesions usually seen in children and adolescents. It has an aggressive character with a high recurrence rate. Mandible is more affected than maxilla and psammomatoid type is more common than trabecular type histologically. Bone resection is generally preferred for the treatment due to nature of the tumor. Here we report a rare case of trabecular type JOF located in the mandible of an 8-year-old child treated by conservative surgeryÖğe Adezyon molekülleri ve ekstraselüler matriks proteinlerinin odontojen lezyonların biyolojik davranışları üzerine etkisinin değerlendirilmesi(İstanbul Medipol Üniversitesi Diş Hekimliği Fakültesi, 2016) Tüfekçioğlu, Şükran; Delilbaşı, Barış ÇağrıGerçek kistler vücudun diğer kemiklerine oranla çene kemiklerinde daha sık bulunur. Bu durum ağız dokularında kist oluşturabilecek çok sayıda odontojen epitel kalıntılarının varlığı ile açıklanabilir. Çoğu oldukça yavaş büyüme özelliği gösteren bu kistler, iltihapsal ve gelişimsel kistler olmak üzere iki ana sınıfa ayrılır. Bunların içinde gelişimsel bir kist olan odontojen keratokist (OKK) yerel nüks oranının yüksek oluşu ve agresif klinik davranışı nedeniyle diğer ağız kistlerinden ayrılmaktadır. Bu özellikler ağızda en çok görülen benign bir odontojen tümör olan ameloblastomun klinik seyri ile benzeşmektedir. Çalışmamızda parakeratotik odontojen kist (pOKK), ameloblastom ve dentigeröz kistlerin (DK) yerel yinelemelesi ve lokal agresif davranışlarıyla; ekstraselüler matriks proteinleri ve adezyon molekülleri arasındaki ilişki değerlendirildi. Değerlendirme ekstraselüler matriks proteinlerinden laminin ve kollagen; adezyon moleküllerinden ise E- kadherin, ? -catenin ve ICAM antikorları ile yapıldı. DK' ların tüm boyamalarda pOKK ve Ameloblastoma göre istatistiksel olarak anlamlı derecede güçlü boyandığı tespit edildi. Sonuç olarak; pOKK ve ameloblastomun DK' dan az boyanmaları, yüksek yerel yineleme ve lokal agresif davranışlara sahip olması ile ilişkili olduğunu düşündürmektedir.Öğe Alveol kret yetersizliğinin extraoral otojen onley kemik greftleri ile ogmentasyonda tünel ve krestal isizyon tekniklerinin karşılaştırılması(Yeditepe Üniversitesi, 2019) Develi, Tuba; Süzen, Muazzez; Altıparmak, Nur; Özel, Abdullah; Uçkan, SinaAmaç: Bu çalışmanın amacı alveoler kret yetersizliğinde krestal ve tünel olmak üzere 2 farklı insizyon tekniği kullanılarak ekstraoral donör sahadan alınan otojen kemik greftin yerleştirilmesinden sonra meydana gelen alıcı bölgedeki komplikasyonların karşılaştırılması ve değerlendirilmesidir. Gereç ve Yöntem: Bu çalışmada 13 hastadaki iliak greft ile ogmente edilen 14 krestal, 27 tünel yöntemi olmak üzere 41 bölgedeki minör (greftte minör açılma, vida başının açılması, sütur açılması, geçici parestezi, ılımlı ve/veya orta şiddette enfeksiyon) ve majör (greft kaybına neden olan enfeksiyon, majör açıklık, kalıcı parestezi) komplikasyonlar retrospektif olarak değerlendirilmiş ve iki farklı insizyon tekniği karşılaştırılmıştır. Ayrıca donör saha morbiditeleri değerlendirilmiştir. Bulgular: Tünel insizyon tekniği kullanılan grupta minor komplikasyon oranı %29.6 iken majör komplikasyon görülmemiştir. Krestal insizyon yapılan grupta % 50 minör komplikasyon ve %28.6 majör komplikasyon görülmüştür. İki farklı insizyon tekniği kullanılan gruplar arasında minör ve majör komplikasyon oranlarında istatistiksel olarak anlamlı fark bulunmuştur. İlaveten krestal teknikte ogmente edilen bölge sayısı ile minör komplikasyon oluşma riski insidansı arasında anlamlı ters korelasyon görülmüştür. Sonuç: Ekstraoral otojen greftlerde subperiosteal tünel yaklaşımı krestal yaklaşıma göre alıcı saha komplikasyon oranı dikkate alındığında daha başarılı ve alternatif bir yöntem olabilir.Öğe Alveolar ridge splitting versus autogenous onlay bone grafting: Complications and implant survival rates(Lippincott Williams & Wilkins, 2017) Altıparmak, Nur; Akdeniz, Sıdıka Sinem; Bayram, Burak; Gülsever, Serap; Uçkan, SinaPurpose:To compare the complications and implant survival rates of localized alveolar ridge deficiencies in the horizontal dimension reconstructed by alveolar ridge splitting (ARS) or autogenous onlay bone grafting (OBG).Materials and Methods:Twenty-eight ARS and 28 OBG were performed. The survival rate of the all included implants was evaluated using the clinical and radiographical evaluation criteria of Misch et al. Temporary exposure of graft, mild infection, temporary paresthesia, and bad split were defined as minor complications; permanent exposure of graft, loss of graft, and permanent paresthesia were defined as major complications. Major and minor complications of ARS and OBG groups were statistically compared.Results:When the minor and major complication rates are considered, there was not any statistically significant difference between OBG (P = 0.099) and ARS (P = 0.241) groups. The satisfactory survival rate of OBG group was 92% and was 100% in the ARS group, and the difference was not statistically significant (P = 0.116).Conclusion:When reconstructing vertically sufficient but horizontally insufficient alveolar ridges, ridge splitting technique could shorten the treatment period, decrease postoperative swelling and pain, eliminate the need for a second surgical site, reduce the treatment cost, and ease the patient cooperation to the surgery.Öğe An alternative distraction osteogenesis method for atrophic posterior mandible: Case report(Inonu University, 2021) Deniz, Kağan; Uçkan, Sina; Şenel, FirdevsVertical lenghtening by distraction osteogenesis has been widely used for reconstruction of dentoalveolar defects. However if bone height between the alveolar crest and the anatomical structures is insufficient, performing an appropriate osteotomy and placement of distractors in desired position is impossible. In the presented case sagittal lengthening of the posterior mandible with distraction osteogenesis was achieved. After horizontal augmentation of the crest by intraoral cortical bone graft, 2 implants were inserted to the distraction area.Öğe An unusual presentation of an intraosseous epidermoid cyst of the anterior maxilla: a case report(BioMed Central Ltd., 2014) Ertem, Sinan Yasin; Uçkan, Sina; Özdemir, Binnaz HandanIntroduction. Intraosseous epidermoid inclusion cysts are rare benign epithelial inclusion cysts in the bone. They are usually found in the cranium and hand phalanges. They are slow growing lesions, and it is difficult to differentiate them from other inflammatory and cystic lesions. Only a few cases of epidermoid inclusion cyst in the jaw have been reported in the literature. This is the fourth case reported as intraosseous epidermoid cyst of the maxilla in the English literature. Case presentation. An asymptomatic 59-year-old Caucasian man was referred to our Oral and Maxillofacial Surgery clinic for a unilocular radiolucent area at his anterior maxilla shown on an orthopantomograph. He was scheduled for surgery and underwent cyst extraction surgery. A pathological examination revealed epidermoid cyst. The diagnostic dilemma in this case report in opposition to the presented intraosseous epidermoid cysts in the literature is that there was no trauma history to his upper jaw. Treatment for this cyst is conservative surgical excision and recurrence is uncommon. Conclusions: This report presents an unusual case of an intraosseous epidermoid cyst that occurred with no trauma history to the upper jaw. Although only three cases of epidermoid inclusion cyst have been reported in the maxilla, epidermoid inclusion cyst should be considered in the differential diagnosis of radiolucent lesions of the jaws.Öğe Analysis of gull in flight appearance and related parameters following le fort i osteotomy(Lippincott Williams & Wilkins, 2021) Süzen, Muazzez; Dilaver, Emrah; Uçkan, SinaThe present study aimed to investigate how "Gull in Flight" appearance and alar-columellar relationship change following maxillary surgery. Thirty-three patients who underwent Le Fort I osteotomy with or without mandibular osteotomy were included in this retrospective study. Measurements which were angle of columella triangle, alar-rim angle, columella lobular angle, and distance of points forming "Gull in Flight" appearance were evaluated on pre and postoperative frontal and lateral photos of patients. Data was submitted to statistical analysis and significance level was determined as 0.05. Following Le Fort I surgery, distance of points forming "Gull in Flight" appearance with respect to canthus was decreased significantly (P < 0.05). Positions of these points to each other were not changed (P > 0.05). Every 1 mm maxillary impaction led to 0.58 mm reduction in y3 (the distance from the point that illustrates Gull's body) (P = 0.032). There was a decrease in angle of columella triangle, alar-rim angle and increase in columella lobular angle. However, these changes were not found significant (P > 0.05). Angle of columella triangle was increased 2.51 degree for every 1 mm maxillary advancement (P = 0.028). In conclusion, maxillary surgery had an impact on nasal region from frontal view. However, "Gull in Flight" appearance which is one of the aesthetic parameters in nose was not changed following maxillary surgery.Öğe Analysis of inferior nasal morphology and nostrils following Le Fort I osteotomy(Lippincott Williams and Wilkins, 2022) Süzen, Muazzez; Dilaver, Emrah; Ak, Kıvanç Berke; Uçkan, SinaObjective: This study aimed to investigate the soft tissue parameters related to inferior nasal morphology and nostril shape and investigate the change at nostril types according to the Modified Topinard System following maxillary surgery. Materials and Methods: Thirty-five patients who underwent Le Fort I osteotomy with or without mandibular osteotomy were included in this retrospective study. Presurgery (T1) and postsurgery (T2) measurements which were the angle between the longitudinal axis of left and right nostril, nostril length, nostril width, alar width, alar base width, columella length, and columella width, were measured on computed tomography images. Nostril types according to Modified Topinard System and nostril shapes were also examined. Results: Following Le Fort I surgery, there was a significant increase in alar base width, alar width, and angle between the longitudinal axis of the left and right nostril (P<0.05). Nasal tip protrusion was decreased with significance (P=0.022). Multiple linear regression analysis showed that every 1 mm maxillary impaction amount leads to a 3.34 degrees increase in the angle between the longitudinal axis of the left and right nostrils (P=0.03, adjusted R (2)=0.21). Nostril type classification according to Modified Topinard System was changed significantly (P=0.000). Conclusion: Surgeons should be aware of the risk of postoperative nonaesthetic results in Modified Topinard System's borderline cases. Modified Topinard classification may be included in preoperative orthognathic planning from the bottom view.Öğe Analysis of relationship between haller cells and schneiderian membrane thickness(2021) Dilaver, Emrah; Akbulut, Aslıhan; Delilbaşı, Barış ÇağrıObjective: This first aim of this study was to determine whether there is a relationship between the presence of Haller cells and Schneiderian membrane thickness (SMT) by considering factors such as age and gender. The second aim of this study was to investigate correlation between the visibility of Haller cells on cone beam computed tomography (CBCT) and digital panoramic radiographs. Materials and Methods: Seventy-eight edentulous patients were included in the study. Cross-sectional views obtained from CBCTs were used to determine the mean sinus membrane thickness. Parameters such as gender and age were also investigated. Results: The difference in SMT at the base of the maxillary sinus was significant between those with and without Haller cells (p <0.05). A correlation was found between the detection of Haller cells on CBCT and digital panoramic radiographs (p <0.01). Although SMT was higher in men than in women, this difference was not significant (p> 0.05). Conclusion: Considering the results of our study, the presence of Haller cells may cause sinus membrane thickness at base of maxillary sinus. Since Haller cells can also be seen in digital panoramic radiographs, digital panoramic view taken prior to sinus lift surgery can provide clinicians with preoperative hint about SMT.Öğe Analysis of select esthetic nasal parameters in virtually planned orthognathic patients(Springer, 2023) Özel, Abdullah; Elbir, Begüm; Çukurova Yılmaz, Zeynep; Uçkan, SinaPurposeBony changes after orthognathic surgery are always followed by changes of the overlying soft tissues. Therefore, morphologic changes of the nose may be expected after procedures involving the maxilla. The purpose of this study was to evaluate the changes in the nasal region due to orthognathic surgery using computed tomography (CT) images of virtually planned patients.Methods35 patients who underwent Le Fort I osteotomy, with or without bilateral sagittal split osteotomy, were included. 3D measurements on preoperative and postoperative images were performed and analyzed.ResultsThe results revealed that aesthetically acceptable results can be achieved by orthognathic surgery alone.ConclusionsAccording to the results of this study, it can be concluded that it is best to reserve decisions on rhinoplasty to the post-orthognathic period.Öğe Antirezorptif ilaç reçete eden tıp hekimlerinin MRONJ yaklaşımı(Türkiye Klinikleri, 2021) Şenol, Gamze; Güldiken, İpek Necla; Süzen, Muazzez; Koçyiğit, Hayrunisa; Delilbaşı, ÇağrıAmaç: Diş çekimi gibi çene üzerinde cerrahi işlem uygulandığında, kemik iyileşmesinin bozulmasıyla çenenin bifosfonat ilişkili nekrozu meydana gelebilir. Bifosfonat kullanan hasta sayısının her geçengün artması ve çenelerin ilaçlara bağlı gelişen osteonekrozu (MRONJ)olgularındaki yükseliş, hekimlerin bu komplikasyonla karşılaşma ihtimalîni artırmaktadır. Hekimler, diş hekimleri ve hastalar tarafındanMRONJ farkındalığı; erken teşhis, tedavi ve önlenmesi açısındanönemlidir. Bu çalışmada, antirezorptif ve antianjiyojenik ilaçları reçeteeden tıp doktorlarının, ciddi bir komplikasyon olan MRONJ ile ilgilifarkındalıklarını ve yaklaşımlarını değerlendirmek amaçlanmıştır.Gereç ve Yöntemler: Araştırmaya bazı üniversite hastaneleri, eğitimve araştırma hastaneleri ve özel sağlık kurumlarında çalışan; ortopedi,dahiliye, romatoloji, fizik tedavi ve rehabilitasyon ve onkoloji uzmanları dâhil edilmiştir. Katılan hekimlere, bifosfonatlar ve MRONJ hakkındaki bilgileri, tedavi sürecindeki yaklaşımları ile ilgili 15 sorudanoluşan bir anket formunu yanıtlamaları istenmiştir. Bulgular: Çalışmayakatılan hekimlerin %46'sı asistan, %54'ü uzman doktordur. Hekimlerin%74'ü bu ilaçları osteoporoz tedavisi için reçete ederken, %47'si alendronatı tercih ettiklerini belirtmişlerdir. Hekimlerin %21’i tedavi öncesidental muayeneyi önerirken, %51’i dental tedaviyi hastanın şikâyeti olduğunda önerdiğini bildirmiştir. Hekimlerin %22’si bifosfonat grubuMRONJ ile karşılaştığını bildirmiştir. Ayrıca hekimlerin uzmanlık alanları arasında, bifosfonata bağlı çene nekrozu hakkında bilgi durumudağılım oranları açısından istatistiksel olarak anlamlı farklılık bulunmaktadır. Bununla beraber hekimlerin %16’sı bifosfonat grubu ilaç kullanımına bağlı çene nekrozu hakkında bilgisinin olmadığını bildirmiştir.Sonuç: Bifosfonat grubu ilaçları reçete eden tıp hekimlerinin, çenelerdegelişen MRONJ hakkındaki farkındalıklarının artması için bifosfonatlarve MRONJ ile ilgili eğitim stratejileri oluşturulmalıdır.Öğe Assessment of hygiene habits and attitudes among removable partial denture wearers in a university hospital(Medknow Publications, 2015) Çakan, Umut; Yüzbaşıoğlu, Emir; Kurt, Hanefi; Kara, Haluk; Turunç, Rana; Akbulut, Aslıhan; Aydın, KaderAims: The aim of this study was conducting a survey of hygiene habits and use of removable partial dentures (RPDs) and correlate them with the social conditions of the interviewees. Methods: A total of 145 RPD wearers were interviewed by experienced clinical staff using a structured questionnaire. A Chi-squared test was performed to evaluate statistical significance between the variables, and the level of significance was P < 0.05. Results: A total of 72 (49%) patients reported that they had not been well informed by the dentists. Brushing was the most frequent cleaning method (57.6%). 77 (53.1%) patients did not take off their dentures at night. The frequency of cleaning dentures and using cleansing tablet was significantly higher in females than in males (P < 0.05). The frequency of denture cleaning, cleaned parts of denture, use of cleansing tablet, removal of dentures at night, frequency of tooth brushing, does not show any significant difference according to age, educational status or duration of denture usage (P > 0.05). RPD wearers did not clean their dentures and natural teeth satisfactorily and had limited knowledge of denture cleansing and oral hygiene maintenance. Conclusions: Hygiene habits and attitudes may be affected by gender, but education level and hygiene attitudes may not always present positive correlation. Dentists should thoroughly inform patients about the harmful effects of overnight wearing and motivate to clean metal parts of RPD's and cleansing tablet use in order to minimize the abrasive effect of widely preferred cleaning method of brushing with toothpaste.Öğe Assessment of nasal respiration and three-dimensional airway volume changes in orthognathic surgery patients(2024) Koçyiğit Daştan, Hayrunisa; Temiz, Mustafa; Münevveroğlu, Sümer; Uçkan, SinaObjectives: The aim of this study was to evaluate the effect of maxillary movements in orthognathic surgery on nasal airway volume change and its correlation with airflow and resistance. Materials and methods: This study included 25 patients (8 male, 17 female) with Class II (6 patients) or Class III (19 patients) malocclusion. All patients underwent Le Fort I and bilateral sagittal split ramus osteotomy. Nasal airflow and resistance were measured by using rhinomanometry and acoustic rhinometry pre and six months post-operatively. Nasal volume was measured using computed tomography before surgery and six months after surgery. Results: Nasal volume increased in 10 out of 11 patients with CCW (counterclockwise) rotation and decreased in 1 patient while, nasal volume increased in 5 patients with CW (clockwise) rotation and decreased in 9 patients. Superior nasal airway volume increased significantly, while the effects on nasal flow and resistance were not significant. Additionally, no significant correlation was found between airway volume changes and variations in airflow and resistance. Conclusion: CCW rotation in orthognathic surgery patients significantly increased superior nasal airway volume but did not improve nasal airway flow and resistance.Öğe Assessment of surgical complications related to dentalimplant surgery using Clavien-Dindo Classification(Selcuk University Faculty of Dentistry, 2021) Dilaver, Emrah; Ak, Kıvanç Berke; Süzen, Muazzez; Uçkan, SinaBackground: The aim of this study is to evaluate the surgicalcomplications encountered in the implants performed by the same surgeon between 2016-2019 using the Clavien-Dindoclassification used to grade the severity of surgicalcomplications. Methods: This retrospective study includes a total of 1171implants performed in 368 cases undergoing dental implantsurgery. Complications related to the operation were recordedand these complications were evaluated according to theClavien-Dindo Classification system. Possible effects of otherfactors such as age, gender, smoking, Diabetes mellitus andimmediate implant placement on complications were alsoevaluated. Results: A total of 98 complications have been reported,including flap dehiscence, numbness, infection, the apical part ofthe dental implant in the maxillary sinus, lack of primary stability,and cortical bone perforation. Smoking and immediateimplantation were found to be risk factors for flap dehiscence (p<0.05). 54.8% of the complications were in Clavien-Dindo Class Iand 28.5% in Class IIIa. According to the Clavien-Dindoclassification, gender, age, smoking and Diabetes Mellitus didnot increase the severity of the complications encountered. Conclusion: The Clavien-Dindo classification could serve as auseful in dental implant surgery both for standardization ofcomplications and to help clinicians understand theconsequences of complications. Wide range of using theClavien-Dindo classification system would allow comparisons ofdifferent techniques’ outcome in implant surgery among differentsurgeons and centers.Öğe Bilateral sagittal split ramus osteotomy using a conventional osteotome-hammer and a magnetic mallet device: An in vitro comparison(NLM (Medline), 2023) Gençer, R. Çağrı; Özel, Abdullah; Uçkan, İbrahim SinaOBJECTIVE: The conventional chisel osteotome technique (CCOT) and the magnetic mallet osteotome technique (MMOT) with a newly manufactured custom osteotome tip for the magnetic mallet device (MMD) were compared to determine whether magneto-dynamic osteotomies are as reliable for orthognathic surgery as the conventional method. MATERIALS AND METHODS: A custom osteotome tip compatible with a magnetic mallet device was manufactured. Thirty-two fresh 1-year-old sheep hemi-mandibles were chosen for osteotomy procedures to achieve the most human-like results. Sagittal split ramus osteotomies were performed, and lingual fracture pattern (LFP), basis split pattern (BSS), duration of sagittal split osteotomy, and alveolar inferior nerve injury were investigated macroscopically. RESULTS: Six of the defined fracture schemes were observed out of the 27 lingual split patterns. After LFP and BSS evaluation, the unfavorable fracture counts for MMOT and CCOT are 3 and 4, respectively. The macroscopic nerve damage assessment for both groups is 2 for MMOT and 1 for CCOT. Although the average durations are similar in both groups, the difference between MMOT samples is closer. None above showed a significant difference. CONCLUSIONS: MMOT was evaluated as a reliable alternative to CCOT in bilateral sagittal split ramus osteotomy based on the lingual and basis split patterns, duration, and nerve damage findings.Öğe Bir diş hekimliği fakültesi öğrencilerinin hepatit B, hepatit C, HIV seroprevalanslarının ve hepatit B enfeksiyonu ile ilgili bilgi düzeyi, tutum ve davranışlarının değerlendirilmesi: Kesitsel klinik araştırma(Turkiye Klinikleri, 2022) Çukurova Yılmaz, Zeynep; Altaş, Nurcan; Gözetici Çil, BurcuHepatit B virüsü (HBV) enfeksiyonu, toplumumuzda yaygın olarak görülen ve dental işlemler yoluyla diş hekimlerinden hastalara ya da hastalardan diş hekimlerine bulaşabilen bir viral enfeksiyondur. Bu çalışmada, diş hekimliği fakültesi 4 ve 5. sınıf öğrencilerinin HBV enfeksiyonu ile ilgili bilgi düzeylerinin, bu konudaki tutum ve davranışlarının değerlendirilmesi amaçlandı. Buna ek olarak, yüksek bulaşıcılık oranına sahip HBV, hepatit C virüsü (HCV) ve insan immün yetmezliği virüsü [human immunodeficiency virus (HIV)] seroprevalansları değerlendirildi. Gereç ve Yöntemler: Bu kesitsel klinik araştırmada, gönüllülere demografik bilgiler, HBV hakkındaki bilgi düzeyleri, tutum ölçeği ve davranış ölçeği olmak üzere 4 bölümden oluşan çevrim içi anket uygulandı. Öğrencilerin HBV, HCV ve HIV seroprevalanslarının değerlendirilmesinde ise ELISA testi kullanıldı. Bulgular: 4. Sınıf öğrencilerinin bilgi düzeyi skorları ile tutum puan ortalamaları arasında istatistiksel olarak anlamlı farklılık gözlendi (p=0,0001). Bilgi düzeyi yüksek olan öğrencilerin tutum puanı ortalamaları, bilgi düzeyi orta olan öğrencilerden istatistiksel olarak anlamlı derecede yüksek bulundu (p=0,0001). 4. Sınıf öğrencilerinden bilgi düzeyi düşük olan öğrencilerin davranış puanı ortalamaları, bilgi düzeyi orta ve yüksek olan öğrencilerden istatistiksel olarak anlamlı derecede düşük bulundu (p=0,012, p=0,001). 5. Sınıf öğrencilerinin ise bilgi düzeyi, tutum ve davranış puan ortalamaları arasında istatistiksel olarak anlamlı farklılık gözlenmedi (p=0,156, p=0,574). Sonuç: HBV genel bilgi seviyesi ve serolojik test sonuçları yeterli düzeyde görünse de kliniğe yeni başlayan 4. sınıf öğrencilerinden HBV enfeksiyonu hakkında bilgi düzeyi düşük olanların tutum ve davranışlarının daha yetersiz olduğu görüldü. Bu sonuç, sürekli enfeksiyon kontrolü eğitiminin gerekliliğini vurgulamaktadır.Öğe Botulinum toxin treatment of temporomandibular joint pain in patients with bruxism: A prospective and randomized clinical study(NLM (Medline), 2021) Kaya, D. I.; Atao?lu, HanifeBackground: Bruxism is a parafunctional habit, usually performed in sleep, by rhythmic and involuntary teeth being squeezed or squeaked. The most common methods of treatment are the use of occlusal splints. Aims: The aim of this study was to compare the efficacy of occlusal splinting with botulinum toxin administration in the treatment of TMJ pain. Subjects and Methods: For this purpose, 40 patients with bruxism were divided into two groups and one group was treated with occlusal splint and the other group received masseter muscle botulinum toxin injection. Then, the participants in both groups were evaluated in terms of pain, functional movement, and maximum bite force change at 2 weeks, 6 weeks, 3 months, and 6 months. Mann-Whitney U test was used to examine the differences between two independent groups. While Friedman test was used for differences between dependent groups, the Wilcoxon test was used for the differences between two repetitive measurements. Chi-square test was used to examine the relationship between categorical variables. Results: When pain was evaluated, both methods were effective in pain reduction, botulinum toxin injection was found to be less effective in reducing pain but no difference was found between the two methods. The maximum bite force decreased in the 2nd and 6th weeks and increased in the 3rd and 6th months in patients receiving botulinum toxin. In patients using occlusal splints, there was no change until the 3rd month and an increase was seen in the 6th month. In this study, it was observed that low dose BTX-A and occlusal splint use were effective in eliminating bruxism-related pain but not superior to each other. Conclusions: According to these results, low dose botulinum toxin can be considered as an alternative treatment in patients who cannot use occlusal splint for various reasons.Öğe Can CAPRIN-1 be responsible for the recurrence potential of odontogenic keratocysts?(2024) Yıldırımyan, Nelli; Altay, Mehmet Ali; Özbudak, İrem HicranObjectives: The purpose of this retrospective study is to compare dentigerous cysts and odontogenic keratocysts for cytoplasmic activation/proliferation - associated protein-1 antibodies via immunohistochemical staining to obtain a new perspective about the specific behavioural characteristics of odontogenic keratocysts at the molecular level. Material and Methods: Forty dentigerous cysts (DC) and forty odontogenic keratocysts (OKC) tissue samples were examined using immunohistochemical staining to detect cytoplasmic activation/proliferation - associated protein-1 (CAPRIN-1) antibodies. Nuclear and/or cytoplasmic staining was evaluated as "positive". Cell staining rate (%) and cell staining intensity were determined, and a staining intensity distribution (SID) score was calculated for each sample. Cases were considered "negative" if they showed no staining for CAPRIN-1 antibodies, thus were given a SID score of zero. According to the SID scores, the expression levels were rated as negative, mild, moderate, or high. Results: Of 80 samples, 16 that could adversely affect immunohistochemical evaluation were excluded. Ten negative, 21 positive and three negative, 30 positive CAPRIN-1 expressions were observed in DC and OKC groups, respectively. The difference between the negative and positive cases within groups was significant only in the OKC group (P = 0.000). The SID score range and mean were 0 to 160 and 31.1 (SD 35.7) for DC and 0 to 160 and 57.3 (SD 42.3) for OKC groups. CAPRIN-1 expression was significantly higher in the OKC group (P = 0.043). Conclusions: The molecular basis for increased mitotic activity, high recurrence rates or presence of satellite cysts in odontogenic keratocysts may be attributed to the expression of cytoplasmic activation/proliferation - associated protein-1.Öğe Çene cerrahisi hastaları i?lk muayenede ne kadar süre konuşuyorlar?(2019) Şenol, Gamze; Burgaz, İlker; Tüfekçioğlu, Şükran; Uçkan, SinaAmaç: Hastaların ilk muayene sırasında sözleri kesilmeden şikayetlerini aktarma süreleri tıbbın belli alanlarında incelenmiştir ancak bu konuda Ağız Diş ve Çene Cerrahisi bölümünde yapılmış bir araştırma bulunmamaktadır. Bu çalışmanın amacı Ağız, Diş ve Çene Cerrahisi kliniklerine ilk defa başvuran hastaların total konuşma zamanlarının değerlendirilmesidir. Gereç ve Yöntem: Çalışmaya 400 hasta dahil edilmiştir. Hastalar şikayetlerine göre; dentoalveolar cerrahi, temporomandibular eklem, dental implant, oral patoloji, dentofasiyal deformite ve travma olmak üzere 6 gruba ayrılmıştır. Bulgular: Çalışma sonucunda hastaların ortalama konuşma zamanının 27.6 saniye olduğu tespit edilmiştir. En uzun konuşma zamanı 42.3 sn (TME grup), en kısa konuşma zamanı ise 13.5 sn (travma grup) olarak ölçülmüştür. Yaş, cinsiyet ve ortalama konuşma zamanı arasında istatistiksel olarak anlamlı bir fark gözlenmemiştir. Sonuç: Daha ayrıntılı bilgi alabilmek ve hasta memnuniyetini arttırmak için; hastalar şikayetlerini anlatırken sözleri kesilmeden sonuna kadar dinlenmelidir.
