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Öğe A prospective study to evaluate drug use among pregnant women(Springer, 2019) Umar, Rashida Muhammad; Koçberber, Emine Karataş; Beşiroğlu, R.; Şahin, A. K.[Abstract Not Available]Öğe Comparison of estimated glomerular filtration rate using different formulas in Turkish population(2024) Çattık, Büşra Nur; Umar, Rashida MuhammadObjective: Creatinine-based equations are generally used in clinical practice to estimate glomerular filtration rates (GFR), but values are not usually consistent. This study aimed to evaluate the difference between estimated GFR values using different equations. Material and Method: Adult Turkish patients with serum creatinine measurements between January to December 2021 and complete demographic data were included. GFR values were calculated using 5 different formulas. GFR calculated with Cockcroft-Gault were normalized to body surface area and added to the comparison. Difference between GFR values and KDIGO stages were evaluated. Albunin/creatinine ratio (ACR) of patients was also assessed. Result and Discussion: A total of 305 patients with average age of 52.92 years were included. Six different GFR calculations were recorded with median values between 51.70 to 71.77 ml/min/1.73m2. Formula of The Modification of Diet in Renal Disease with the race factor for Turkish population resulted in the lowest eGFR values. The ACR values of only 42 patients were available and it was negatively correlated to all GFR values and positively correlated to all KDIGO stages (p<0.05). There were noteworthy variations in GFR values, based on patient demographics and/or equations. The need for novel practical methods for estimating GFR in general and specific patient populations are necessary.Öğe Drug-drug interactions among hospitalized cancer patients(Springer, 2018) Umar, Rashida Muhammad; Yumuk, Perran Fulden; Apikoğlu Rabuş, Şule[Abstract Not Available]Öğe Drug-related problems identified in hospitalized cancer patients(Springer, 2018) Umar, Rashida Muhammad; Yumuk, Perran Fulden; Apikoglu Rabus, Şule[Abstract Not Available]Öğe Evaluation of disease and medication knowledge levels of diabetic patients(Istanbul University, 2023) Umar, Rashida Muhammad; Çattık, Büşra Nur; Aslan, SelimBackground and Aims: Diabetes mellitus is a public health problem with a significant economic burden to society. Patient attitude is a significant determinant of adherence and clinical outcomes. We aimed to evaluate the disease and medication knowledge level of diabetic patients and possible patient-related predictive factors. Methods: Adult diabetic patients were included in the study. Patients' demographic and health-related data were collected using a pre-prepared form. Two questionnaires, KAP knowledge tool and Medication Assessment tool were used to assess the disease and medication knowledge levels of patients. Results: The mean age of 159 patients was 54.44 & PLUSMN;12.24 years. The disease and medication knowledge scores were high with an average of 13.9 & PLUSMN;1.74 and 5.26 & PLUSMN;0.53, respectively. Higher scores were linked to being male (p=0.042; p=0.007) and higher educational status (p<0.001; p=0.006). Lower scores were recorded in patients with comorbidities (p=0.002; p<0.001), older patients (p<0.001), longer disease duration (p<0.001; p=0.009), longer antidiabetic drug use (p<0.001; p=0.009) and using more drugs (p=0.002; p=0.006). None of the patients could mention any possible side effects of their medications. Conclusion: It can be deduced that patient-related factors are significant predictors of patients' disease and medication knowledge. Patient-specific education in addition to rational pharmacological intervention is necessary to achieve better clinical outcomes.Öğe Evaluation of educational needs of diabetic patients(Faculty of Pharmacy of Ankara University, 2022) Aksoy, Nilay; Öztürk, Nur; Ulusoy, Serel; Umar, Rashida Muhammad; Özaydın, SenaObjective: Our study aimed to assess the role of pre-graduate pharmacy students’ participation in a diabetic education program on improving diabetic self-care. Material and Method: This study included both a cross-sectional and a longitudinal follow-up. Altinbas University fifth-year pharmacy students gathered relevant information from diabetic patients that visited community pharmacies, under the supervision of their instructor pharmacist. The participants filled out the diabetic self-care scale on their first visit before they were given the education. Patients refilled the same self-care questionnaire after three months. Statistical package for the social science (SPSS) 26 was used for all statistical analysis. Result and Discussion: The study comprised 86 diabetic patients. The second questionnaire results showed significant improvement in all patients. The total diabetic self-care scale scores were improved remarkably after the training session. HbA1c and BMI values decreased significantly. An educational program can improve diabetic self-care and diabetic outcomes. Active participation of final year pharmacy students in patient care can also improve pharmacists' participation and contribution to patient care delivery.Öğe Evaluation of medication and herbal product use among pregnant women(Istanbul Medipol University, 2021) Umar, Rashida Muhammad; Beşiroğlu, Rabia; Şahin, Ayşe Kevser; Karataş Koçberber, Emine; Ceylan, CengizhanThe use of medications and herbal products among women increases after pregnancy. The purpose of the study is to evaluate the frequency of medication used and analyzed them based on the FDA pregnancy risk categories. This cross-sectional study was conducted on 300 adult volunteers attending antenatal care in a university-affiliated hospital. Medications were classified according to the FDA pregnancy risk classification. In 97,7% of women, the use of at least one medication during pregnancy. The median count for Category A medications was 2. Category C and B medications were reported by 100 (33,3%) and 53 women (17,7%). There was a significant difference between the education level and the use of herbal products (p=0.043). Pharmacists should take a greater role in educating pregnant women and women of childbearing age about the possible consequences of medications on the development of the fetus and guide healthcare practitioners in choosing the most appropriate medications.Öğe Opinions of the Syrian patients about the effect of language barriers on the quality of pharmacy services received and about the use of pictograms(Springer, 2019) Apikoğlu Rabuş, Şule; Barri, Rama; Al-Saleh, Akram; Umar, Rashida Muhammad[Abstract Not Available]Öğe Significance of a clinical pharmacist-led comprehensive medication management program for hospitalized oncology patients(Springer, 2020) Umar, Rashida Muhammad; Apikoğlu-Rabuş, Şule; Yumuk, Perran FuldenBackground The use of highly toxic drugs in cancer treatment and supportive care medications exposes patients to an increased number of drug-related problems (DRPs). Clinical pharmacists contribute to the optimal use of medications by intervening in identified drug-related problems. Objective To evaluate the relevance of a comprehensive medication management service in oncology patients. Setting Marmara University Teaching and Research Hospital Medical Oncology Ward, Istanbul, Turkey. Methods This prospective study was carried out between December 2015 and April 2016 with adult patients with confirmed malignancy. Comprehensive medication management was performed by the clinical pharmacist throughout the patient's hospital stay. The medication-related data as well as data regarding demographic and general health status of the patients were reviewed for the presence of drug-related problems. The identified problems, interventions and acceptance rate by physicians were recorded with the help of the Pharmaceutical Care Network Europe V6.0 (PCNE) classification. Main outcome measures Number and causes of drug-related problems, nature and acceptance rate of clinical pharmacist interventions and rate of problems solved. Results The study included 137 patients. The mean (SD) age of the patients was 58 (14.6) years. A total of 481 drug-related problems were recorded. The most frequent drug-related problems were 'adverse drug events [including drug interactions]' (n = 376), 'untreated indications' (n = 59) and 'unnecessary drug treatment' (n = 25). Inappropriate combination of drugs was the cause of 73.2% of the total problems. Interventions were made to stop administration of a suitable drug if the combination with another drug was contraindicated while prescribers were mostly informed about major drug interactions. The prescribers approved 93% of the total intervention proposals. The majority (90.9%) of the identified problems were totally solved. Conclusion Integration of clinical pharmacy services through a comprehensive medication management program in oncology will help to reduce the number of drug-related problems.Öğe The prevalence of drug-drug interactions and reported therapy related side-effects in oncology out-patients(Marmara University, 2023) Umar, Rashida Muhammad; Can, Zeynep Yeşim; Güven Eke, Ece; Karataş Koçberber, Emine; Ölmez, Ömer FatihObjective: The use of multiple medications in cancer patients is unavoidable; thus, adverse drug-drug interactions are frequent. This study aims to assess the prevalence of potential drug interactions in oncology patients visiting the outpatient chemotherapy unit. Method: Demographic and health-related information of patients visiting an outpatient chemotherapy unit was recorded using a pre-prepared form. A comprehensive list of all concurrently used medications was compiled and checked for interactions with the Micromedex online drug interaction tool.Results: A total of 179 adult patients were included. We recorded an average of 9.3 drugs per patient with 79 patients using more than 10 drugs. A total of 1671 drugs including 303 chemotherapeutic agents were assessed for drug-drug interactions. A total of 374 interactions, of which 203 were significant, were recorded in 118 (65.9%) patients with an average of 3.2 interactions per patient. Only 46 major interactions were recorded for anticancer agents. Cyclophosphamide (n=13) and cisplatin (n=12) were involved in most interactions. The number of interactions correlated with the number of drugs used (p=.001) and the presence of comorbidities (p=.002). The presence of comorbidities increased the risk of interaction by 1.21 (p=.04). Recorded side effects were not correlated to drug interactions. Conclusion: Medication review in cancer patients is essential in establishing all medications used by patients. Routine assessment in terms of potential drug interactions and evaluation of these interactions by a qualified pharmacist may help in optimizing patient outcomes.
