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Öğe An endotracheal ectopic parathyroid Adenoma mimicking asthma(Amer Coll Chest Physicans, 2015) Seyhan, EkremINTRODUCTION: Ectopic parathyroid glands can be seen from the front of the bifurcation of carotis to pericardium (1). In this case report an ectopic parathyroid adenoma (EPA) obstructing the tracheal lumen, locating in the distal part of the trachea is presented. It has never been reported in the literature before.Öğe Diagnosing latent tuberculosis in immunocompromised patients measuring blood IP-10 production capacity: An analysis of chronic renal failure patients(American College of Chest Physicians, 2015) Seyhan, EkremPURPOSE: Patients undergoing haemodialysis for chronic renal failure (CRF-HD) are at risk of latent tuberculosis infection (LTBI). The effectiveness of using blood IP-10 production capacity to diagnose LTBI in CRF-HD patients was analysed. METHODS: The study enrolled 50 CRF-HD patients. Interferon-gamma release assay (IGRA) was done using Quantiferon G-In-Tube (QFG-IT) system. Blood IP-10 production capacity was measured using the QFG-IT system tubes. Tuberculin skin testing (TST) was performed on the same day and the test results were compared. RESULTS: TST turned out to be positive in 36.4% of the patients and QFG-IT in 54% of them. After stimulation with specific tuberculosis antigens, blood IP-10 levels increased noticeably. The antigen-stimulated blood IP-10 level was significantly higher in patients who were either TST or QFG-IT positive than in patients whose tests were negative (p=0.0001). Using 4.02 pg/mL as the threshold for stimulated blood log-transformed IP-10 level, good agreement was observed between IP-10 and QFG-IT results (?=1). CONCLUSIONS: Blood IP-10 level, which can be measured simply, provides results equivalent to interferon-? release assays for the diagnosis of LTBI in CRF-HD patients.Öğe Red blood cell distribution with in patients With chronic obstructive pulmonary disease(European Respiratory Soc Journals Ltd, 2013) Özgül, Akif; Seyhan, Ekrem; Ömur, İmranBody: Bacgraund: Chronic obstructive pulmonary disease (COPD) increases the risk of cardiovascular disease (CVD). Red blood cell distribution width (RDW) is a newly recognized risk marker in patients with established CVD. It is unknown whether RDW is associated with in COPD patients. Aims: To study value of RDW in patients with COPD and to compare the value of this measurement with cardiac, respiratory, and hemotological status. Method: Two hundred five patients patients with stable COPD and 110 healthy controls cases were enrolled in the study. Demographic, clinical, echocardiographic, and laboratory characteristics were registered in COPD patient. Results: In the overall patients, the RDW level had a mean value of 15.1± 2.1. The RDW values were higher in the COPD group than in the controls (p< 0.001). RDW was positively correlated with C-reactive protein (CRP) (p= 0.008), right ventricular dysfunction (RVD) (P< 0.001), presence of CVD (p<0.01) and pulmonary arterial hypertension (PAH) (P= 0.03). In multivariable logistic regression, the presence of high RDW was the only parameter independently predicting RVD in patients with COPD (odds ratio, 2.098; P = .017). Conclusion: RDW may be used to identify COPD patients with RV failure. RDW is independently associated with cardiovascular disease in patients with COPD.Öğe Usefulness of admission red cell distribution Width as a predictor of early mortality in patients with severe exacerbation of chronic obstructive pulmonary disease(European Respiratory Soc Journals Ltd, 2013) Seyhan, Ekrem; Sokucu, Sinem; Ömür, İmran[Abstract Not Available]
