Yazar "Pek, Reyhan Zeynep" seçeneğine göre listele

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  • Küçük Resim
    Öğe
    Investigating the roles of micrornas / lncrnas in characterizing breast cancer subtypes and prognosis
    (2023) Pek, Reyhan Zeynep; Zavalsız, Muhammed Talha; Serdar, Melis; Alhajj, Lama; Alhajj, Sleiman; Sailunaz, Kashfia; Özyer, Tansel; Rokne, Jon; Alhajj, Reda
    Molecular subtyping is a method of separating tumor clusters in a cancer type with common features according to molecular data and classification models. Genome datasets are taken from many different people and some genetic material, more precisely genetic markers, are obtained to predict the presence of a disease. In addition, breast cancer occurs due to mutation or modification observed in cells. miRNAs and lncRNAs take participation in cell cycle, regulation, and even chromatic inhibition of cell. For example, miRNAs function in cell cycle regulation as the degradation of mRNAs. Therefore, the aim of this work is to investigate the roles of miRNAs and lncRNAs in prognosis and characterizing the subtypes of Breast Cancer.
  • Küçük Resim
    Öğe
    The role of machine learning in identifying students at-risk and minimizing failure
    (IEEE-Institute of Electrical and Electronics Engineers Inc., 2023) Pek, Reyhan Zeynep; Tarıyan Özyer, Sibel; Elhage, Tarek; Özyer, Tansel; Alhajj, Reda
    Education is very important for students' future success. The performance of students can be supported by the extra assignments and projects given by the instructors for students with low performance. However, a major problem is that students at-risk cannot be identified early. This situation is being investigated by various researchers using Machine Learning techniques. Machine learning is used in a variety of areas and has also begun to be used to identify students at-risk early and to provide support by instructors. This research paper discusses the performance results found using Machine learning algorithms to identify at-risk students and minimize student failure. The main purpose of this project is to create a hybrid model using the ensemble stacking method and to predict at-risk students using this model. We used machine learning algorithms such as Naive Bayes, Random Forest, Decision Tree, K-Nearest Neighbors, Support Vector Machine, AdaBoost Classifier and Logistic Regression in this project. The performance of each machine learning algorithm presented in the project was measured with various metrics. Thus, the hybrid model by combining algorithms that give the best prediction results is presented in this study. The data set containing the demographic and academic information of the students was used to train and test the model. In addition, a web application developed for the effective use of the hybrid model and for obtaining prediction results is presented in the report. In the proposed method, it has been realized that stratified k-fold cross validation and hyperparameter optimization techniques increased the performance of the models. The hybrid ensemble model was tested with a combination of two different datasets to understand the importance of the data features. In first combination, the accuracy of the hybrid model was obtained as 94.8% by using both demographic and academic data. In the second combination, when only academic data was used, the accuracy of the hybrid model increased to 98.4%. This study focuses on predicting the performance of at-risk students early. Thus, teachers will be able to provide extra assistance to students with low performance.