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Öğe Synthesis of substituted pyridines from 1,2-nucleophilic addition products of functionalized N-acy1-2,3-dihydropyridones(Pergamon-Elsevier Science, 2015) Güzel, Mustafa; Watts, Joshua; McGilvary, Matthew; Wright, Marcus; Kiren, SezginWe describe herein a general and efficient synthetic approach toward substituted pyridines from functionalized N-acy1-2,3-dihydropyridones in two steps; 1,2-addition with organocerium reagents and subsequent oxidative aromatization with chloranil. This strategy allows the generation of pyridines with various substitution patterns and introduces a variety of substituents including aryl, alkyl, alkynyl, alkenyl, and heteroaryl groups at the desired positions.
