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    Acute effects of exercise on choroidal thickness and ocular pulse amplitude
    (Derman Medical Publishing, 2019) Dervişoğulları, Mehmet Serdar; Totan, Yüksel; Kulak, Ali Ender; Güler, Emre
    Aim: To explore ocular changes in healthy people after exercise. Material and Method: Twenty participants underwent exercise for 15 minutes on a treadmill. Measurements of choroidal thickness, intraocular pressure (IOP), ocular pulse amplitude (OPA), and blood pressure were taken before and after exercise. Enhanced Depth, Imaging optical coherence tomography (EDI-OCT) was used to measure choroidal thickness at the fovea and at the areas 1500 mu m nasal and 1500 mu m temporal to the fovea; IOP and OPA were measured by the dynamic contour tonometer (DCT; Swiss Micro technology AG, Port, Switzerland). Blood pressure was measured concurrently with the acquisition of the scans. Results: Twenty participants (20 eyes) with a mean age of 22.65 +/- 0.98 years were measured. There was a significant increase in systolic and diastolic pressure after exercise (p<0.05). There was a significant decrease in IOP and OPA after exercise (p<0.05). There was no significant difference in the subfoveal, nasal or temporal choroidal thickness measurements after exercise (p>0.05). Discussion: In our study, there was no significant change in the thickness of the choroid after exercise. IOP and OPA significantly decreased, and systolic and diastolic blood pressure significantly increased, after exercise. This indicates an adaptation of vascular resistance due to vasoconstriction. The IOP and OPA decreases do not seem to be related with the changes in choroid thickness.
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    Evaluation of ganglion cell-inner plexiform and retinal nerve fiber layer thicknesses in obese children and their associations with obesity severity and duration
    (Bulent Ecevit University, 2018) Tenlik, Aylin; Kulak, Ali Ender; Güler, Emre; Totan, Yüksel; Gürağaç, Fatma Betül; Boyraz, Mehmet
    Aim: To evaluate the macular ganglion cell-inner plexiform layer (GC-IPL) and the retinal nerve fiber layer (RNFL) thicknessesmeasured by high-definition optical coherence tomography (HD-OCT) in children with obesity and to determine whether thicknessparameters are correlated to disease severity and duration.Materials and Methods: This prospective study involved 40 obese and 40 age and sex-matched non-obese children aged between 6 and17 years. Following the measurement of body mass index (BMI), cycloplegic auto-refraction, intraocular pressure, and axial length (AL)was measured. OCT scans were performed using Cirrus HD-OCT (Carl-Zeiss Meditec, Dublin, CA, USA). Right eye of each subjectwas selected for analysis.Results: The study included 40 healthy children and 40 children with obesity. The RNFL thickness measurements revealed thinner inthe obesity group compared to controls for all quadrants however, the only statistically difference were for the average and superiorquadrants (P < 0.05). All GC-IPL thickness parameters were statistically thinner in the obese subjects compared to the controls (P< 0.05). Average peripapillary RNFL and macular GC-IPL thicknesses and some quadrants and sectors are inversely correlated withdisease severity and duration.Conclusions: Macular GC-IPL and peripapillary RNFL thicknesses were significantly lower in obese children than controls and anegative correlation between the severity and duration of obesity and both the GC-IPL and RNFL thicknesses could indicate that obesitycontrol in children may be a crucial strategy for prevention of glaucoma.