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  • Küçük Resim Yok
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    Could the long-term oncological safety of laparoscopic surgery in low risk endometrial cancer be also valid for the high intermediate and high-risk patients? A multi-center Turkish gynecologic oncology group study conducted with 2745 endometrial cancer cases
    (BMJ Publishing Group, 2019) Vardar, Mehmet Ali; Güzel, Ahmet Barış; Taşkın, Selen; Güngör, Mete; Özgül, Nejat; Salman, Coşkun; Küçükgöz Güleç, Ümran; Khatib, Ghada; Dunder, Ivan; Ortaç, Fırat; Yüce, Kutluay; Terek, Coşan Mustafa; Şimşek, Tayup; Özsaran, Aydın; Taşkıran, Çağatay; Onan, Anıl Mehmet; Çoban, Gonca; Topuz, Samet; Demirkıran, Fulya; Takmaz, Özgüç; Köse, Mehmet Faruk; Göçmen, Ahmet; Seydaoğlu, Gülşah; Gümürdülü, Derya; Ayhan, Ali
    [Abstract Not Available]
  • Küçük Resim
    Öğe
    Could the long-term oncological safety of laparoscopic surgery in low-risk endometrial cancer also be valid for the high–intermediate-and high-risk patients? A multi-center turkish gynecologic oncology group study conducted with 2745 endometrial cancer cases. (TRSGO-End-001)
    (MDPI, 2021) Vardar, Mehmet Ali; Güzel, Ahmet Barış; Taşkın, Selen; Güngör, Mete; Özgül, Nejat; Salman, Coşkun; Küçükgöz Güleç, Ümran; Khatib, Ghada; Taşkıran, Çağatay; Dünder, İlkkan; Ortaç, Fırat; Yüce, Kunter; Terek, Coşan; Şimşek, Tayup; Özsaran, Aydın; Onan, Anıl; Çoban, Gonca; Topuz, Samet; Demirkıran, Fuat; Takmaz, Özgüç; Köse, Mehmet Faruk; Göçmen, Ahmet; Seydaoğlu, Gülşah; Gümürdülü, Derya; Ayhan, Ali
    This study was conducted to compare the long-term oncological outcomes of laparotomy and laparoscopic surgeries in endometrial cancer under the light of the 2016 ESMO-ESGO-ESTRO risk classification system, with particular focus on the high–intermediate-and high-risk categories. Using multicentric databases between January 2005 and January 2016, disease-free and overall survivals of 2745 endometrial cancer cases were compared according to the surgery route (laparotomy vs. laparoscopy). The high–intermediate-and high-risk patients were defined with respect to the 2016 ESMO-ESGO-ESTRO risk classification system, and they were analyzed with respect to differences in survival rates. Of the 2745 patients, 1743 (63.5%) were operated by laparotomy, and the remaining were operated with laparoscopy. The total numbers of high–intermediate- and high-risk endometrial cancer cases were 734 (45%) patients in the laparotomy group and 307 (30.7%) patients in the laparoscopy group. Disease-free and overall survivals were not statistically different when compared between laparoscopy and laparotomy groups in terms of low-, intermediate-, high–intermediateand high-risk endometrial cancer. In conclusion, regardless of the endometrial cancer risk category, long-term oncological outcomes of the laparoscopic approach were found to be comparable to those treated with laparotomy. Our results are encouraging to consider laparoscopic surgery for high–intermediate- and high-risk endometrial cancer cases.