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Akut santral seröz korioretinopatide düşük doz asetilsalisilik asitin tedavi ve nüks üzerine etkisi
(Gazi Eye Foundation, 2016) Eliaçık, Mustafa; Karaman, Sevil; Anıl Aslan, Cemile; Şentürk, Fevzi; Aras, Cengiz; Kaya, Faruk
Amaç: Akut santral seröz korioretinopatide (SSKR) tedaviye eklenen düşük doz asetilsalisilik asitin tedavi ve nüks üzerine olan etkilerinin incelenmesi amaçlandı. Gereç ve Yöntem: Çalışmamız Kasım 2010-Kasım 2013 tarihleri arasında kliniğimiz retina birimine başvuran ve SSKR tanısı almış 60 hastanın 60 gözüne ait verilerin retrospektif olarak incelenmesi ile gerçekleştirildi. Tüm hastaların demografik özellikleri ile görme keskinlikleri ve optik koherens tomografi ile saptanan maküler kalınlıkları kayıt altına alındı. Hastalar iki gruba ayrıldı. Grup A'daki hastalar tedavileri süresince oral asetozolamid ve topikal nepafenak %0.1 kullanan hastalardan oluşturulurken, Grup B'deki hastalar ise bu tedaviye ek olarak düşük doz asetilsalisilik asit kullanılmışlardı. Gruplar yaş, cinsiyet, görme keskinliği, maküler kalınlık ve nüks durumu açısından karşılaştırıldı. Bulgular: İlk muayenedeki görme keskinliği asetilsalisilik asit kullanmayan grupta LogMAR 0.15±0.11 iken asetilsalisilik asit kullanan grupta LogMAR 0.18±0.13 idi (p=0.43). Tedavi öncesi ortalama maküla kalınlığı asetilsalisilik asit kullanmayan hastalarda 406±61 m iken asetilsalisilik asit kullanan hastalarda 407±56 m olarak ölçüldü (p=0.879). Yapılan istatistiksel değerlendirmeye göre takip süresi boyunca 1. hafta, 1.,3. ve 6. aylarda ölçülen görme keskinlikleri ve maküla kalınlıkları açısından her iki grup arasında istatistiksel bir farklılığa rastlanılmadı. Grup A'daki hastaların (n=32) 12'sinde (%37) takip süresince ikinci bir atak oluşurken, bu sayının Grup B'de (n=28) 4 (%14) olduğu görüldü(p=0.04). Sonuç: Akut SSKR hastalarında oral asetozolamid ve topikal nepafenak %0.1 tedavisine eklenen düşük doz asetilsalisilik asitin fonksiyonel ya da anatomik iyileşme üzerine yararlı artı bir etkisi gözlenmemektedir. Ancak asetilsalisilik asit kullananlarda kullanmayanlara göre nüks daha az görülmektedir.
Change in choroidal thickness after intravitreal injection for treatment of neovascular age-related macular degeneration: Ranibizumab versus aflibercept
(Masson Editeur, 2017) Kaya, Faruk
Purpose. - To compare the changes in subfoveal choroidal thickness after intravitreal ranibizumab or aflibercept injections for neovascular age-related macular degeneration (nAMD).Methods. - In this retrospective study, 28 eyes with nAMD treated with 3 consecutive monthly injections of ranibizumab (IVR) and 24 eyes with nAMD treated with 3 consecutive monthly injections of aflibercept (IVA) between September 2012 and June 2016 were reviewed. The follow-up time was 6 months. Changes in two groups' best-corrected visual acuity (BCVA) and subfoveal choroidal thickness by using enhanced depth imaging optical coherence tomography at 1st, 3rd and 6th months were recorded and compared.Results. - Choroidal thickness decreased significantly in eyes treated with IVR (P=0.015, 0.01 and 0.01, respectively) or IVA (P=0.001, 0.001 and < 0.001, respectively) at 1, 3 and 6 months examination but IVA treated eyes presented a significantly further reduction in choroidal thickness when compared with ranibizumab (P=0.03, 0,04 and 0.03, respectively). There was no significant difference between aflibercept and ranibizumab group when change in BCVA from baseline compared at 1, 3 and 6th months (P=0.54, 0.06 and 0.37, respectively). There was no correlation between change in choroidal thickness and the BCVA outcomes in either group.Conclusions. - Subfoveal choroidat thickness decreased significantly after both of IVR and IVA injections in patients with nAMD. In conclusion, intravitreal injections of ranibizumab or aflibercept affect not only neovascular lesion but also the underlying choroid.
Comparison of different formulas for intraocular lens power calculation using a new optical biometer
(Masson Editeur, 2015) Kaya, Faruk; Koçak, İbrahim; Aydın, Ali; Baybora, Hakan; Karabela, Yunus
Purpose. - To evaluate and compare the predictability of different formulas for intraocular lens (IOL) power calculation using a new optical biometer (Aladdin). Methods. - This prospective cross-sectional study included 70 eyes of 70 patients who underwent uneventful phacoemulsification with IOL implantation. Preoperative IOL power calculations were performed using the Aladdin optical biometer. Postoperative actual refractive errors and errors predicted by the SRK/T, SRK II, Holladay 1, Hoffer Q and Haigis formulas were analyzed. The mean estimation error (EE), mean absolute estimation error (AEE) and the percentage of eyes within +/- 0.50 and +/- 1.00 D of the target refraction for each of five formulas were calculated and compared. This analysis was also repeated in three groups formed based on axial length (AL) (group 1: <22.5 mm, group 2: 22.5-24 mm, group 3: > 24 mm). Results. - In the overall study group, the smallest mean AEE was provided by the Holladay 1 formula, however there was no statistically significant difference in the mean AEE's predicted by the five formulas (P = 0.34). The highest percentage of eyes within +/- 0.50 and +/- 1.00 D of the target refraction was also found by using Holladay 1 (71% and 97%). SRK/T provided smallest mean AEE for groups 1 (n = 13) and 3 (n = 16). In group 2 (n = 41), the smallest mean AEE was obtained using Holladay 1. Conclusions. - Based on the Aladdin biometric data used in our study, better results can be obtained using SRK/T formula in eyes with short or long AL. The Holladay 1 formula may be preferred in eyes with moderate AL.
Comparison of intraocular lens power calculation using a standard ultrasonic biometer and a new optical biometer
(International Journal of Ophthalmology Press, 2016) Kaya, Faruk; Koçak, İbrahim; Aydın, Ali; Baybora, Hakan; Karadayı, Koray
AIM:To compare the intraocular lens (IOL) power calculations and refractive outcomes obtained with a new optical biometer and standard ultrasonic biometer in phacoemulsification surgery. METHODS:Thirty-seven eyes of 37 cataract patients who underwent phacoemulsification with IOL implantation were included in this prospective comparative study. The same operator performed biometer measurements in eyes with cataract using a new optical biometer (Aladdin) and a standard ultrasonic biometer (Sonomed AB 5500). Biometric parameters; axial length (AL), keratometric (K) readings, anterior chamber depth (ACD) and IOL power obtained by two devices were recorded. Postoperative actual refractive errors and errors predicted by two devices according to SRK/T formula were analyzed. The mean estimation error (EE), mean absolute estimation error (AEE) and the biometric parameters obtained by two biometers were compared. RESULTS:The AL measured by Aladdin (23.45±0.73 mm) was significantly longer than AL by ultrasonic biometer (23.2±0.75 mm) (P=0.01). The mean EE and AEE values obtained by Aladdin were significantly smaller than the values by ultrasonic biometer (P=0.0006 and 0.03 respectively). The higher percentage of eyes within ±0.5 and ±1.00 D of target refraction was also found by using Aladdin (67% and 97%). CONCLUSION:The Aladdin optical biometer showed better accuracy and yielded better refractive outcomes compared with ultrasonic biometer.
Comparison of intravitreal afl ibercept and ranibizumab for macular edema secondary to branch retinal vein occlusion
(Gazi Göz Vakfı, 2018) Kaya, Faruk; Koçak, İbrahim; Aydın, Ali; Baybora, Hakan; Koç, Hacı; Karabela, Yunus
Purpose: To compare the effi cacy of intravitreal injection of ranibizumab and afl ibercept on the treatment of macular edema due to branch retinal vein occlusion (BRVO). Materials and Methods: In this retrospective study; eyes with macular edema secondary to BRVO which treated with intravitreal ranibi- zumab (IVR) or afl ibercept( IVA) and followed at least 12 months between September 2012 and March 2016 were reviewed. Mean number of injections and changes in two groups’ best-corrected visual acuity (BCVA) and central macular thickness (CMT) measured by optical coherence tomography at month 1, 3, 6 and 12 were reviewed and compared. Results: Mean BCVA improved signifi cantly in IVR group (p=0.03, 0.04, 0.02 and 0.03 respectively) and IVA group (p=0.02, 0.04, 0.03 and 0.03 respectively ; and CMT decreased signifi cantly in IVR group (p=0.02, 0.02, 0.02 and 0.03 respectively) and IVA group (p=0.001, 0.03, 0.01 and 0.02 respectively) at 1, 3, 6 and 12th months. Mean number of injections per eye within twelve months were 3.4±1.2 in rani- bizumab group, and 2.2±1.1 in afl ibercept group (p=0.03). There were no signifi cant differences between two groups at month 12, including fi nal BCVA, changes in BCVA, fi nal CMT, and changes in CMT (p> 0.05) Conclusion: Afl ibercept presented similar decrease in CMT and improvement in BCVA with lesser number of injections for macular edema due to BRVO.
Comparison of transepithelial corneal collagen crosslinking with epithelium-off crosslinking in progressive keratoconus
(Masson Editeur, 2014) Koçak, İbrahim; Aydın, Ali; Kaya, Faruk; Koç, Hacı
Purpose. - To evaluate the safety and efficacy of transepithelial corneal collagen crosslinking (TE-CXL) as compared to epithelium-off crosslinking (epi-off CXL) in progressive keratoconus. Methods. - Records of keratoconus patients treated with TE-CXL or epi-off CXL were reviewed retrospectively. Patients were included if they had at least 12 months follow-up. Pre- and postoperative measurements of visual acuity, refractive errors, keratometry, corneal topography and pachymetry were assessed and compared. Results. - There was no statistically significant difference between two groups at baseline in terms of demographic, refractive and corneal parameters. Mean maximum cone apex curvature (apical K) increased from 51.62 +/- 5. Eighty-four diopters (D) to 53.70 +/- 5.49 D in the TE-CXL group (n = 17), and decreased from 52.02 +/- 4.07 D to 51.22 +/- 3.51 in the epi-off CXL group (n = 19) at the end of the follow-up period. The difference between two groups was statistically significant (P = 0.0002). An increase of >= 1D in apical K was observed in two of 19 eyes (11%) in the epi-off CXL group, and 11 of 17 eyes (65%) in TE-CXL group at the last follow-up visit, compared to baseline (P < 0.0001). Fourteen patients in the epi-off CXL group exhibited corneal edema that resolved without haze with topical corticosteroid treatment by 4 months. No postoperative corneal edema was observed in TE-CXL group. Conclusions. - Although it is safe and well tolerated, TE-CXL does not effectively halt the progression of keratoconus. Epi-off CXL appears to be effective in stopping progression and even improves corneal parameters. (C) 2014 Elsevier Masson SAS. All rights reserved.
Corneal flap thickness with the Moria M2 single-use head 90 microkeratome in 72 consecutive LASIK procedures
(Dove Medical Press Ltd, 2017) Karabela, Yunus; Muftuoğlu, Orkun; Kaya, Faruk
Purpose: This study aimed to evaluate the accuracy and consistency of corneal flap thickness in laser-assisted in situ keratomileusis (LASIK) with the Moria M2 single-use head 90 microkeratome. Methods: The central corneal thickness of 72 (37 right, 35 left) eyes of 37 patients was measured by ultrasonic pachymetry preoperatively and intraoperatively after flap cut. The Moria M2 single-use head 90 microkeratome was used to create a superior hinged flap in all eyes. The right eyes were always operated on before the left eyes in each patient, using the same blade in all bilateral cases. All patients underwent LASIK for myopia and/or myopic astigmatism using VISX Star S4 platform. Results: The mean preoperative spherical equivalent refraction was -3.55 +/- 2.30 D (range: -0.625 to -11.00 D), preoperative central corneal thickness by ultrasonic pachymetry was 541 +/- 26.82 mu m (490-600 mu m) and steepest K was 44.08 +/- 1.49 D (40-46.75 D) in all eyes. The mean flap thickness was 136.97 +/- 20.07 mu m (106-192 mu m), 131.2 +/- 19.5 mu m (91-192 mu m), and 134.16 +/- 19.85 mu m (91-192 mu m) in the right, left, and both eyes, respectively. A positive significant relationship was found between flap thickness and preoperative ultrasonic pachymetry thickness. No significant relationship was found between flap thickness and the age, preoperative spherical equivalent, and preoperative steepest K. The difference between the first and second eyes was not significant. There were no major intraoperative and postoperative complications in all eyes. Conclusion: The Moria M2 single-use head 90 microkeratome cut relatively thicker flaps than were intended. The flap thickness range was quite wide. This was a disadvantage for the accuracy and consistency of corneal flap thickness.
Diyabetik maküla ödemi tedavisinde intravitreal bevacizumab
(Gazi Göz Vakfı, 2015) Koçak, İbrahim; Koç, Hacı; Aydın, Ali; Baybora, Hakan; Kaya, Faruk
Diyabetik maküla ödemi (DMÖ) olgularında intavitreal bevacizumab (İVB) enjeksiyon tedavisinin etkinlik ve güvenilirliğini araştırmak.Gereç ve Yöntem: DMÖ nedeniyle İVB tedavisi yapılan olguların dosyaları retrospektif olarak taranmış, en iyi düzeltilmiş görme keskinliği (EDGK) ve optik koherens tomografiyle elde edilen merkezi maküla kalınlığı (MMK) değişiklikleri istatistiksel olarak analiz edilmiştir.Bulgular: DMÖ nedeniyle takip edilen ve İVB enjeksiyonu yapılan yirmi dört hastanın 34 gözü çalışmaya alındı. İVB tedavisi sonrası ortalama takip süresi 14.3±5.2 ay olarak hesaplandı. Tedavi öncesi EDGK 0.99±0.59 logMar (snellen ile 0.1) seviyesinden 0.73±0.52 (snellen ile 0.2) seviyesine ulaştı (p=0.0018). MMK ise 505±142 µm seviyesinden 427±156 µm seviyesine geriledi (p=0.0016). Yedi gözde (%20) son kontrolde tedavi öncesine göre EDGK değişikliği olmadı. Sekiz gözde (%23) bir sıra veya daha fazla EDGK artışı oldu. Üç gözde (%8) bir sıra veya daha fazla EDGK azalması oldu. On dokuz gözde (%56) >=%10 MMK azalması görüldü. Altı gözde (%18) >=%10 MMK artışı görüldü. Retina dekolmanı, vitreus hemorajisi, endoftalmi gibi intravitreal enjeksiyonlar sonrası görülebilen komplikasyonlar görülmedi.Sonuç: Çalışmamızın sonuçlarına göre İVB'in DMÖ tedavisinde etkin ve güvenli bir yöntem olduğu söylenebilir. Her geçen gün daha yaygın bir şekilde kullanılan bu tedavi yöntemi, laser fotokoagulasyon gibi klasik tedavi yöntemlere ek olarak veya alternatif olarak tercih edilebilir.
Effect of aflibercept on persistent macular edema secondary to central retinal vein occlusion
(Masson Editeur, 2018) Kaya, Faruk; Koçak, İbrahim; Aydın, Ali; Baybora, Hakan; Koç, Hacı; Karabela, Yunus
Purpose. - To evaluate the efficacy of switching treatment from intravitreal ranibizumab to intravitreal aflibercept on the treatment of refractory macular edema secondary to central retinal vein occlusion (CRVO). Methods. - In this retrospective study; 12 eyes with refractory macular edema secondary to CRVO after multiple monthly repeated intravitreal 05 mg/0.05 mL ranibizumab injections prior to switching therapy to intravitreal 2 mg/0.05 mL aflibercept, between March 2012 and April 2016 were reviewed. The follow-up time was 12 months. Changes in best-corrected visual acuity (BCVA), central macular thickness (CMT), central retinal volume (CRV) and injection interval between baseline and month 1, 3, 6 and 12 after switching therapy to aflibercept were reviewed and evaluated. Results. - Mean baseline CRT decreased from 516 +/- 101 mic. to 252 +/- 114 mic.at month 12 (P=0.008). Mean baseline CRV decreased from 8.74 +/- 2.13mm(3) to 6.82 +/- 1.64mm(3) at month 12 (P=0.005). Baseline BCVA improved from 0.73 +/- 0.21 to 0.53 +/- 0.17 logMAR at month 12 (P=0.004). Mean BCVA gain was two logMar lines (10 letters) at month 12. After switching therapy to aflibercept; the mean injection interval increased significantly from 1.34 months at baseline to 1.86 months at month 12, by an increase of 0.52 months (P=0.02). Conclusion. - Intravitreal aflibercept is evaluated to be presenting significant visual and anatomical improvements in patients with persistent macular edema due to CRVO despite previous intravitreal ranibizumab.
Effect of periodontitis on dry eye disease signs and symptoms: a cross-sectional study
(2024) Kaya, Faruk; Kızıltan Eliaçık, Başak; Koç, Hacı; Eliaçık, Mustafa
PURPOSE: Gingivitis and periodontitis are oral disorders characterised by chronic inflammation, impacting the supportive structures around teeth due to bacterial accumulation. While the role of inflammation in both periodontitis and dry eye disease (DED) has been established individually, their potential association remains unclear. This study aimed to investigate the association between periodontitis and the manifestation of signs and symptoms related to DED in patients aged 18-40. MATERIALS AND METHODS: A cross-sectional study was conducted involving healthy controls, DED patients with or without periodontitis, and patients with periodontitis without DED. Ophthalmic and oral examinations were performed, and demographic, ocular, and systemic disease data were collected. Statistical analysis was conducted using ANOVA and chi-squared tests. RESULTS: A total of 684 participants were included in the study. Significant elevations in tear osmolarity levels, increased Ocular Surface Disease Index scores (OSDI), and decreased tear break-up time (TBUT) and Schirmer (ST-I) values were observed in DED patients with periodontitis compared to individuals with DED but without periodontitis, as well as control and periodontitis groups. Furthermore, higher neutrophil-to-lymphocyte ratios (NLR) were found in DED patients with periodontitis. CONCLUSION: The findings suggest an association between periodontitis and the severity of signs and symptoms related to DED. The study highlights the importance of interdisciplinary approaches in understanding the systemic implications of periodontal disease and its potential impact on ocular health.
Effects of dorzolamide/timolol fixed combination on retrobulbar hemodynamics in pseudoexfoliative glaucoma
(Elsevier Taiwan, 2016) Eliaçık, Mustafa; Erdur Karaman, Sevil; Altıok Baltepe, İnci; Gülkılık, Gökhan; Aslan Anıl, Cemile; Kaya, Faruk
In our study we aimed to evaluate the short-term effects of dorzolamide/timolol on ocular perfusion pressure and retrobulbar blood flow in patients with pseudoexfoliative glaucoma (PXG). This prospective observational cross-sectional study enrolled 22 eyes of 22 newly-diagnosed patients with PXG in a single center. All of the patients received a fixed combination of dorzolamide/timolol. Besides routine ophthalmologic examination, the retrobulbar hemodynamic parameters in the ophthalmic artery, central retinal artery, and short posterior ciliary arteries were measured in all participants at baseline and the 3rd month using color Doppler imaging. The mean intraocular pressure (IOP) was 22.3 +/- 2.1 mmHg at baseline and reduced to 17.4 +/- 2.3 mmHg at the 3rd month (p < 0.05). None of the retrobulbar parameters, except peak systolic velocity and resistive index in temporal short posterior ciliary arteries, changed significantly on therapy with dorzolamide/timolol fixed combination when the results were analyzed at Month 3. The drug significantly decreased the peak systolic velocity (p = 0.044) and reduced the resistive index in 0.04 units, 95% confidence interval 0.03-0.05, (p < 0.001) in the temporal short posterior ciliary arteries. This study reports that the retrobulbar hemodynamics might be affected less than expected by dorzolamide/timolol fixed combination in patients with PXG although the reduction of IOP was statistically significant.
Efficacy of radial keratotomy in the optical rehabilitation of mild to moderate keratoconus cases
(International Journal of Ophthalmology, 2015) Koçak, İbrahim; Aydın, Ali; Kaya, Faruk; Baybora, Hakan; Bozkurt, Salih
AIM: To investigate the efficacy of radial keratotomy (RK) for the optical and visual rehabilitation of mild to moderate keratoconus. METHODS: Thirty-one eyes of 22 keratoconus patients with at least 12 mo follow-up were recruited and reviewed retrospectively. Uncorrected visual acuity (UCVA), best spectacle corrected visual acuity (BSCVA), autorefractometer values, keratometric values, corneal irregularity indexes, and complications were analyzed pre- and post-operatively. RESULTS: At the last follow-up visit, mean UVCA (logMAR) improved significantly from 0.86±0.34 to 0.30±0.29 (P<0.0001), and mean BSCVA (logMAR) improved from 0.47±0.21 to 0.17±0.23, (P<0.0001). Mean keratometric values decreased from 48.69±3.68 to 44.33±3.09 diopters (P<0.0001). Mean spherical equivalent measured by autorefractometer was also improved significantly from -5.61±2.85 to -2.29±1.95 at the last follow-up visit (P<0.0001). Central corneal thickness and corneal irregularity index of 3 mm and 5 mm zones did not change during the overall follow-up time. No serious intraoperative or postoperative complication was observed. CONCLUSION: RK is assessed as an effective treatment method for the optical and visual rehabilitation of mild to moderate keratoconus cases, according to our results in a selected group of keratoconus patients.
Epithelium-off corneal cross-linking in progressive keratoconus: 6-year outcomes
(Masson Editeur, 2019) Kaya, Faruk
Purpose. - To evaluate the long-term results of corneal collagen cross-linking (CXL) with epithe-lium removal in patients with progressive keratoconus. Methods. - This retrospective study included 27 eyes of 18 patients who underwent CXL surgery for progressive keratoconus between April 2009 and March 2012. Best-corrected visual acuity (BCVA), manifest refraction spherical equivalent (SE), maximum keratometry reading (K max), mean of the minimum and maximum keratometry readings (mean-K), central corneal thickness (CCT), and anterior and posterior elevation at the apex preoperatively and year 1, 3 and 6 were evaluated and compared. P values < 0.05 were considered to be statistically significant. Results. - Mean BCVA was 0.35 +/- 0.28 logMAR preoperatively and 0.23 +/- 0.20 logMAR 6 years after the procedure (P = 0.01). Mean SE decreased from -4.3 +/- 2.45 diopters (D) to -3.91 +/- 2.12 D (P = 0.03). Mean K max decreased from 49.6 +/- 3.2 D to 48.6 +/- 2.8 D (P = 0.04), and mean-K decreased from 47.6 +/- 2.5D to 46.9 +/- 2.6 D (P = 0.04). CCT decreased insignificantly from 466.5 +/- 32.1 mu m to 465.4 +/- 26.6 mu m (P = 0.65). Mean anterior elevation at the apex decreased from 12.8 +/- 7.9 to 12 +/- 8.3 mu m (P = 0.04), and posterior elevation decreased from 27.1 +/- 17.4 mu m to 26.8 +/- 18.5 mu m (P = 0.27). Mean-K, max-K, BCVA and CCT showed no change over the last 5 years. After the first year, no significant change was observed in BCVA, SE, max-K, mean-K and CCT, which were therefore considered stable. On the other hand, anterior and posterior elevation readings continued to decrease up to 6 years after CXL. Conclusion. - Based on our 6-year results, CXL can halt progression of keratoconus and reduce the need for keratoplasty.
Evaluation of bacterial contamination rate of the anterior chamber during phacoemulsification surgery using an automated microbial detection system
(International Journal of Ophthalmology Press, 2014) Koçak, İbrahim; Koçak, Funda; Teker, Bahri; Aydın, Ali; Kaya, Faruk; Baybora, Hakan
AIM: To assess the incidence of anterior chamber bacterial contamination during phacoemulsification surgery using an automated microbial detection system (BacT/Alert). METHODS: Sixty nine eyes of 60 patients who had uneventful phacoemulsification surgery, enrolled in this prospective study. No prophylactic topical or systemic antibiotics were used before surgery. After antisepsis with povidone iodine, two intraoperative anterior chamber aqueous samples were obtained, the first whilst entering anterior chamber, and the second at the end of surgery. BacT/Alert culture system was used to detect bacterial contamination in the aqueous samples. RESULTS: Neither aqueous samples obtained at the beginning nor conclusion of the surgery was positive for microorganisms on BacT/Alert culture system. The rate of bacterial contamination during surgery was 0%. None of the eyes developed acute onset endophthalmitis after surgery. CONCLUSION: In this study, no bacterial contamination of anterior chamber was observed during cataract surgery. This result shows that meticulous surgical preparation and technique can prevent anterior chamber contamination during phacoemulsification cataract surgery.
Fakoemülsifikasyon ile kombine arka kapsüloreksisten silikon yağı çıkarılması
(Gazi Göz Vakfı, 2016) Kaya, Faruk; Koçak, İbrahim; Aydın, Ali; Baybora, Hakan; Bozkurt, Salih
Amaç: Tamponat olarak silikon yağı kullanılmış pars plana vitrektomi (PPV) sonrası katarakt hastalarında, kombine fakoemülsifikasyon ve arka kapsüloreksisten silikon yağı çıkarılması tekniğinin sonuçlarını ve komplikasyonlarını değerlendirmek.Gereç ve Yöntem: Retrospektif çalışmamıza PPV ve silikon yağı (SY)ameliyatı sonrası katarakt gelişmiş olan, kombine fakoemülsifikasyon ve arka kapsüloreksisten SY çıkarılması ameliyatı uygulanan 27 hastanın 29 gözü dahil edildi. Ameliyat sonrası tüm hastalar 1. gün, 1. hafta, 1. ay, 3. ay, 6. ay kontrollerine çağrılarak; tashihli görme keskinliği (GK), göz içi basıncı (GİB), ön segment bulguları, fundus bulguları ve gelişen komplikasyonlar not edildi. Karşılaştırmalar, normal dağılımlar için student-t testi kullanılarak yapıldı. p değeri 0.05 altında istatistiksel olarak anlamlı kabul edildi. Bulgular: Hastaların primer ameliyatları olan PPV ve SY tamponadının en sık nedeni proliferatif diyabetik retinopati (PDR) zemininde gelişen vitreus hemorajisi idi (%34). Hastaların ameliyat öncesi ortalama 1.26±0.65 logMAR olan GK, son kontrolde ortalama 0.95±0.64 (02) logMAR olarak tespit edildi. Görme keskinliğindeki artış istatistiksel olarak anlamlı değildi (p=0.07). Hastaların %79.3'ünde (23/29) GK arttı. 4 hastamızda GİL sulkusa implante edilirken, 25 hastada katlanabilir akrilik göz içi lensi kapsül içine implante edildi. Ameliyat sonrası erken dönemde en sık karşılaşılan komplikasyon %31 (9/29) ile kornea ödemi olurken, geç dönemde en sık karşılaşılan komplikasyon %13.8 (4/29) ile glokom oldu. Sonuç: Fakoemülsifikasyon ile kombine arka kapsüloreksisten silikon yağı çıkarılması, retinaya ek müdahale gerekmeyen seçilmiş vakalarda daha az travmatik, güvenli, hızlı ve erken görsel rehabilitasyon açısından etkili bir yöntemdir.
Katarakt cerrahisinde ön kapsül temizliğinin arka kapsül opaklaşması süresi üzerine etkisi
(2013) Baybora, Hakan; Aydın, Ali; Koçak, İbrahim; Kaya, Faruk
Fakoemülsifikasyon yöntemiyle sorunsuz katarakt cerrahisi yapılan ve göz içi lensi (GİL) konulan hastalarda cerrahi esnasında gerçekleştirilen ön kapsül temizliğinin (ÖKT) arka kapsül opaklaşması (AKO) süresi üzerine etkisini araştırmak. Gereç ve Yöntem: Geriye dönük olarak yapılan bu çalışmada, yaşa bağlı katarakt sebebiyle servisimizde ameliyat edilmiş, sonrasında AKO gelişmesi sonucu görme keskinliğinin 0.5’in altına düşmesiyle Nd:YAG lazer kapsülotomi uygulanmış has- taların dosyaları gözden geçirildi. Bu hastalardan; ameliyat sırasında ÖKT yapıldıktan sonra aynı tipte keskin kenarlı GİL konmuş ve ameliyat sonrası 1. ay, 6. ay ve yıllık kontrolleri kayıt altına alınmış olgular saptandı. Bu olgularla aynı dönemde ameliyat edilmiş ancak ÖKT uygulanmamış, sonrasında gelişen AKO sebebiyle kapsülotomi yapılmış birbirini takip eden hastalardan aynı olgu sayısında bir kontrol grubu oluşturuldu. İki grubun klinik özellikleri ve Nd:YAG lazer kapsülotomiye gidiş zamanları istatistiksel olarak karşılaştırıldı. Bulgular: ÖKT yapılmış grup ve kontrol grubu 37 hastanın 37 gözünden oluştu. Ortalama yaş ÖKT grubunda 63.73±11.64 (49-78) yıl, kontrol grubunda 63.14±10.6 (45-77) yıldı. ÖKT grubunda hastaların 15’i erkek (%41), 22’ si kadın (%59), kontrol grubunda ise 20’si erkek (%54), 17’ si kadındı (%46). Ortalama kapsülotomiye gidiş zamanı ÖKT grubunda 35.65±8.82 (18- 59) ay, kontrol grubunda ise 27.48±8.99 (10-33) aydı. Bu süre ÖKT grubunda istatistiksel olarak daha uzundu (p<0.001). Sonuç: Ön kapsülde lens kalıntılarının temizlenmesi AKO gelişimini engellememekle birlikte ortaya çıkış zamanını geciktirmektedir
MRI results of patients with acute isolyted cranial nerve palsies
(Turkish Neurosurgical Society, 2020) Baybora, Hakan; Kaya, Faruk; Koçak, İbrahim; Karabela, Yunus
AIM: To investigate the magnetic resonance imaging (MRI) results of patients complaining from diplopia with ocular nerve palsy.MATERIAL and METHODS: A routine ophthalmic examination was performed, a neurological consultation was requested, and cranial MRI was performed for all patients. The image results were sorted into four groups: ischemic lesions, demyelinating disease lesions, tumors, and no lesions. White matter gliosis and cerebral infarcts were included in the ischemic lesion group. The medical histories of the patients were acquired from medical records. The chi-squared test was used to analyze the relationship between age and cranial MRI images and to analyze the relationship between the image and paresis type. The statistical significance threshold was set at p<0.05, unless otherwise stated.RESULTS: Ischemic MRI images were the most common image type seen in our study. Third nerve paresis was significantly correlated with ischemic cerebral lesions observed by MRI (p=0.009). Furthermore, lesions were significantly correlated with patients aged above 50 years (p=0.004). There were no significant correlations between fourth or sixth nerve paresis and cranial ischemic images (p=0.680 and p=0.678, respectively). There were two instances of cerebral artery aneurysm, three instances of cerebral infarct, and one instance of intracranial mass, all in patients aged over 50 years.CONCLUSION: Although our patients had minimal or nonexistent neurological symptoms, some had serious cranial pathologies. These pathologies were commonly seen in patients aged over 50 years. We recommend performing MRI on all patients with binocular diplopia.
Performance of the SRK/T formula using A-Scan ultrasound biometry after phacoemulsification in eyes with short and long axial lengths
(BioMed Central Ltd., 2016) Karabela, Yunus; Eliaçık, Mustafa; Kaya, Faruk
Background: The SRK/T formula is one of the third generation IOL calculation formulas. The purpose of this study was to evaluate the performance of the SRK/T formula in predicting a target refraction ±1.0D in short and long eyes using ultrasound biometry after phacoemulsification. Methods: The present study was a retrospective analysis, which included 38 eyes with an AL < 22.0 mm (short AL), and 62 eyes ?24.6 mm (long AL) that underwent uncomplicated phacoemulsification. Preoperative AL was measured by ultrasound biometry and SRK/T formula was used for IOL calculation. Three different IOLs were implanted in the capsular bag. The prediction error was defined as the difference between the achieved postoperative refraction, and attempted predicted target refraction. Statistical analysis was performed with SPSS V21. Results: In short ALs, the mean age was 65.13 ± 9.49 year, the mean AL was 21.55 ± 0.45 mm, the mean K1 and K2 were 45.76 ± 1.77D and 46.09 ± 1.61D, the mean IOL power was 23.96 ± 1.92D, the mean attempted (predicted) value was 0.07 ± 0.26D, the mean achieved value was 0.07 ± 0.63 D, the mean PE was 0.01 ± 0.60D, and the MAE was 0.51 ± 0.31D. A significant positive relationship with AL and K1, K2, IOL power and a strong negative relationship with PE and achieved postoperative was found. In long ALs, the mean age was 64.05 ± 7.31 year, the mean AL was 25.77 ± 1.64 mm, the mean K1 and K2 were 42.20 ± 1.57D and 42.17 ± 1.68D, the mean IOL power was 15.79 ± 5.17D, the mean attempted value was -0.434 ± 0.315D, the mean achieved value was -0.42 ± 0.96D, the mean PE was -0.004 ± 0.93D, the MAE was 0.68 ± 0.62D. A significant positive relationship with AL and K1, K2 and a significant positive relationship with PE and achieved value, otherwise a negative relationship with AL and IOL power was found. There was a little tendency towards hyperopic for short ALs and myopic for long ALs. The majority of eyes (94.74 %) for short ALs and (70.97 %) for long ALs were within ±1 D of the predicted refractive error. No significant relationship with PE and IOL types, AL, K1, K2, IOL power, and attempted value, besides with MAE and AL, K1, K2, age, attempted, achieved value were found in both groups. Conclusion: The SRK/T formula performs well and shows good predictability in eyes with short and long axial lengths.
Psödoeksfolyasyonlu katarakt olgularında ön segment biyometrik değerlendirmesi
(Düzce Üniversitesi Tıp Fakültesi, 2017) Koç, Hacı; Koçak, İbrahim; Kaya, Faruk; Baybora, Hakan; Aydın, Ali
Amaç: Bu çalışmanın amacı katarakt olgularında psödoeksfolyatif sendromun (PXS), merkezi kornea kalınlığı (MKK), ortalamakeratometre (K), ön kamara derinliği (ÖKD) ve lens kalınlığı (LK) gibi biyometrik parametrelere etkisini araştırmaktır.Gereç ve Yöntemler: Kliniğe müracaat eden kataraktı ve PXS’u olan hastalar çalışmaya alındı. Çalışmaya alınan hastalar PXS vekontrol grubu olmak üzere iki gruba ayrıldı. Bütün hastalarda en iyi düzeltilmiş görme keskinliği (EDGK) tespiti, biyomikroskop ileön segment muayenesi, non-kontakt tonometre ile göz içi basıncı (GİB) ölçümü ve fundus muayenesi yapıldı. Ayrıca, bu hastalarınpakimetri, ÖKD ve LK ölçümleri, optik biyometri ve A-scan ultrasonografi cihazlarıyla alındı ve iki grubun verileri karşılaştırıldı.Bulgular: Gruplar arasında yaş, cinsiyet, en iyi düzeltilmiş görme keskinliği, katarakt evresi ve göz içi basıncı açısından anlamlı birfark bulunmadı. PXS grubunda MKK 530±35,22 µm, K 44,22±1,55 dioptri, ÖKD 3,21±0,34 mm, LK 4,63±0,25 mm, AU 23,42±0,74mm olarak bulunmuştur. Kontrol grubunda MKK 536±30,45 µm, K 44,01±1,49 dioptri, ÖKD 3,14±0,32 mm, LK 4,51±0,30 mm, AU23,36±0,61 mm olarak bulunmuştur. Bu parametreler açısından iki grup arasında istatistiksel olarak anlamlı bir fark bulunmamıştır.Sonuç: Bu çalışmada, MKK, K, ÖKD ve LK ile PXS arasında anlamlı bir ilişki görülmemiştir. Ancak özellikle MKK ve ÖKDparametreleri ile ilgili olarak literatürde farklı sonuçlar bildirilmiştir. Bu farklı sonuçlar; ırksal farklılıklar, farklı yaş dağılımları, metotfarklılıkları ve farklı örneklem büyüklükleri ile ilgili olabilir.
Pupil barycenter configuration in patients with myopia and hyperopia
(Springer, 2022) Koç, Hacı; Kaya, Faruk
Purpose To compare the apparent chord mu between hyperopia and myopia cases and investigate the usefulness of iris barycenter configurations as an alternative for performing kappa angle distance calculations. Methods This prospective study evaluated 394 eyes of 197 patients classified into two groups according to their spherical equivalent values: the myopic (mean spherical equivalent refraction <= - 0.50 D) and the hyperopia group (mean spherical equivalent refraction >= + 0.50 D). The two groups were further subdivided according to severity (myopic group: mild, <= - 0.50 and <= - 3.00 D; moderate, < - 3.00 and <= - 6.00 D; severe, < - 6.00 D; hyperopic group: mild, >= + 0.50 and <= + 2.00 D; moderate, > + 2.00 and <= + 4.00 D; severe, > + 4.00 D). The pupil and iris barycenter distance measurements and other parameters were obtained through optical low-coherence reflectometry. Results Of the 197 patients, 109 (55.3%) were female and 88 (44.7%) were male individuals; their ages ranged from 7 to 60 years (mean, 35.16 +/- 14.75 years). The average pupil barycenter distances were 0.38 +/- 0.15 and 0.21 +/- 0.11 mm in hyperopia and myopia patients, respectively (p < 0.01). Corneal and lens thickness measurements were higher in hyperopia patients (p < 0.01, p < 0.01, respectively), whereas anterior chamber depth and pupil diameter measurements were higher in myopia patients (p < 0.01, p < 0.01, respectively). No significant difference in astigmatism or white-to-white measurements was observed between hyperopia and myopia patients (p > 0.05). Conclusion The measurements for the apparent chord mu of the pupil and iris barycenter origins were higher in hyperopic than in myopic cases.

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