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Yazar "Hajebrahimi, Farzin" seçeneğine göre listele

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    Assessement of balance in geriatric hypertensive individuals
    (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2016) Hajebrahimi, Farzin; Algun, Zeliha Candan; Özbek, Hanefi
    Our study is designed to evaluate the relationship between the balance performance of the geriatric hypertensive and normotensive individuals and find out the effect of hypertension in the balance behavior of the elderly people. 61 geriatric people were included in our study. All the patients were 65 years old and older and were participating to our study with their own approval. Demographic information of the participants has been recorded. Basic activities of daily living is measured by the KATZ Index of ADLs, cognitive status is measured by Standardized Mini-Mental State Examination, depression status is measured by Geriatric Depression scale, Quadriceps muscle strength is measured by hand held dynamometer, ankle dorsiflexion range of motion is measured by goniometer, gait is measured by Timed Up and Go Test and balance performance is measured by Nintendo Wii and Pedalo® Sensamove balance device. The systolic and diastolic blood pressure is measured before the balance test. Hypertensive group had higher performance time in Timed Up and Go test than normotensive. (p=0.030). There was no statistically significant difference in parameters of Pedalo® Sensamove device between hypertensive and normotensive participants (p>0.05). Parameters of "Completed seconds in Wii Single Leg Balance Test", "Performance score in Wii Single Leg Balance Test" and "Wii fit age" between both hypertensive and normotensive were determined significant in the statistical analysis (p<0.05). Hypertension seems to affect different parameters of balance among elderly people. For controlling their balance, elderly people should consider their high blood pressure beside their falling history.
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    Clinical evaluation and resting state fMRI analysis of virtual reality based training in Parkinson's disease through a randomized controlled trial
    (Nature Research, 2022) Hajebrahimi, Farzin; Velioğlu, Halil Aziz; Bayraktaroğlu, Zübeyir; Helvacı Yılmaz, Nesrin; Hanoğlu, Lütfü
    There are few studies investigating the short-term effects of Virtual Reality based Exergaming (EG) on motor and cognition simultaneously and pursue the brain functional activity changes after these interventions in patients with Parkinson's Disease (PD). The purpose of this study was to investigate the synergistic therapeutic effects of Virtual Reality based EG on motor and cognitive symptoms in PD and its possible effects on neuroplasticity. Eligible patients with the diagnosis of PD were randomly assigned to one of the two study groups: (1) an experimental EG group, (2) an active control Exercise Therapy (ET) group. All patients participated in a 4-week exercise program consisting of 12 treatment sessions. Every session lasted 60 min. Participants underwent a motor evaluation, extensive neuropsychological assessment battery and rs-fMRI before and after the interventions. Thirty patients fulfilled the inclusion criteria and were randomly assigned to the EG and ET groups. After the dropouts, 23 patients completed the assessments and interventions (11 in EG, 13 in ET). Within group analysis showed significant improvements in both groups. Between group comparisons considering the interaction of group x time effect, showed superiority of EG in terms of general cognition, delayed visual recall memory and Boston Naming Test. These results were consistent in the within-group and between-group analysis. Finally, rs-fMRI analysis showed increased activity in the precuneus region in the time x group interaction in the favor of EG group. EG can be an effective alternative in terms of motor and cognitive outcomes in patients with PD. Compared to ET, EG may affect brain functional connectivity and can have beneficial effects on patients' cognitive functions and motor symptoms. Whenever possible, using EG and ET in combination, may have the better effects on patients daily living and patients can benefit from the advantages of both interventions.
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    Cross-cultural adaptation, validity and reliability of Turkish version of Oxford Ankle Foot Questionnaire for children with congenital talipes equinovarus & nbsp
    (Elsevier, 2021) Hajebrahimi, Farzin; Tarakçı, Devrim; Arman, Nilay; Emir, Ahmet; Bursalı, Ayşegül; Tarakçı, Ela
    Background: The purpose of the study was to evaluate the reliability and validity of the Turkish version of the Oxford Ankle Foot Questionnaire (OxAFQ) to provide cultural adaptation. Methods: This study involved translation, back translation, and cross-cultural adaptation. Forty-nine patients with congenital talipes equinovarus were evaluated using the Turkish version of OxAFQ. Turkish version of the Childhood Health Assessment Questionnaire (CHAQ) was used as a gold standard to validate the Turkish version of the OxAFQ. The validation was assessed with Spearman correlation analysis by using CHAQ. The reliability of the questionnaire was assessed with Cronbach alpha (internal consistency) and exploratory factor analysis. Results: High validity was found between OxAFQ and CHAQ (r =-0.422-0.292) (p < 0.01). Reliability analysis showed that OxAFQ had a high level of Cronbach alpha (alpha = 0.88-0.96) and internal consistency (ICC = 0.90-0.96). Conclusion: The Turkish version of OxAFQ is a valid, reliable and useful quality of life questionnaire in patients with congenital talipes equinovarus and it is proper for use by health professionals and researchers.
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    Disabled children's functionality and maternal quality of life and psychological status
    (Wiley, 2016) Yıldız, Aysel; Tarakçı, Devrim; Hajebrahimi, Farzin; Mutluay, Fatma
    Background: Physiotherapy is being provided for different disabled groups in pediatric rehabilitation centers. The quality of life (QOL) and psychological status of the mothers of these children is affecting their compliance in the rehabilitation period. The aim of this study was therefore to assess the relationship between disability level of individuals receiving rehabilitation and maternal QOL, psychological status and influencing factors. Methods: One hundred and twenty-six disabled children and their mothers were included in this cross-sectional study. Demographic information was noted. Child motor level was assessed using the Gross Motor Function Classification System and the level of independency in activities of daily living (ADL) was assessed with the Katz ADL scale. Maternal QOL was assessed with the 36-item Short Form (SF-36), and psychological status with the Beck Depression Inventory (BDI). SPSS 18.0 was used to analyze data. Results: Mean maternal age was 36.46 +/- 7.2 years. Of the children, 67.5% had physical problems, 16.7% had mental problems, 7.9% had autism, 4.8% had hyperactivity, and 3.2% had hearing and speaking problems. Mild depression was detected in mothers (mean BDI score, 11.27 +/- 8.1). There was no correlation between child disability level and maternal QOL and depression (P > 0.05). Maternal BDI score was negatively correlated with all SF-36 subscale scores (P < 0.001 for all parameters). Conclusion: The SF-36 subscale scores of mothers of disabled children were decreased compared with Turkish community norms. Psychological support of mothers of children in the rehabilitation period may positively affect this period.
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    Functional neural networks stratify Parkinson's disease patients across the spectrum of cognitive impairment
    (Wiley, 2024) Hajebrahimi, Farzin; Budak, Miray; Sarıcaoğlu, Mevhibe; Temel, Zeynep; Kahraman Demir, Tuğçe; Hanoğlu, Lütfü; Yıldırım, Süleyman; Bayraktaroğlu, Zübeyir
    Introduction Cognitive impairment (CI) is a significant non-motor symptoms in Parkinson's disease (PD) that often precedes the emergence of motor symptoms by several years. Patients with PD hypothetically progress from stages without CI (PD-normal cognition [NC]) to stages with Mild CI (PD-MCI) and PD dementia (PDD). CI symptoms in PD are linked to different brain regions and neural pathways, in addition to being the result of dysfunctional subcortical regions. However, it is still unknown how functional dysregulation correlates to progression during the CI. Neuroimaging techniques hold promise in discriminating CI stages of PD and further contribute to the biomarker formation of CI in PD. In this study, we explore disparities in the clinical assessments and resting-state functional connectivity (FC) among three CI stages of PD.Methods We enrolled 88 patients with PD and 26 healthy controls (HC) for a cross sectional clinical study and performed intra- and inter-network FC analysis in conjunction with comprehensive clinical cognitive assessment.Results Our findings underscore the significance of several neural networks, namely, the default mode network (DMN), frontoparietal network (FPN), dorsal attention network, and visual network (VN) and their inter-intra-network FC in differentiating between PD-MCI and PDD. Additionally, our results showed the importance of sensory motor network, VN, DMN, and salience network (SN) in the discriminating PD-NC from PDD. Finally, in comparison to HC, we found DMN, FPN, VN, and SN as pivotal networks for further differential diagnosis of CI stages of PD.Conclusion We propose that resting-state networks (RSN) can be a discriminating factor in distinguishing the CI stages of PD and progressing from PD-NC to MCI or PDD. The integration of clinical and neuroimaging data may enhance the early detection of PD in clinical settings and potentially prevent the disease from advancing to more severe stages.
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    İnme sonrası uygulanan ev temelli ayna terapisi ve kognitif terapatik egzersizlerin üst ekstremite fonksiyonlar üzerine etkisi
    (İstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, 2022) Çakmaklı, Muhammed Ahmet; Hajebrahimi, Farzin
    İnme, ileri derecede özürlülük oranına sahip olan, yüksek tekrarlama oranı ve üst seviyelerdeki ölüm oranı ile akut başlangıçlı bir hastalıktır. Bu çalışmanın amacı, inmeli bireylerde ev temelli ayna terapisi ve kognitif terapatik egzersizlerin üst ekstremite fonksiyonlarına, kongisyona, depresyona ve yaşam kalitesine etkisini incelemekti. Çalışmaya 30 inmeli birey dahil edildi ve randomize olarak Ayna Terapisi (AT) grubu (n=15) ve Ayna Terapisi (AT) + Kognitif Terapi (KT) grubu olarak iki gruba ayrıldı. Her iki gruptaki bireylere 1 saatlik seans şeklinde, haftada 3 gün, 8 hafta boyunca toplam 24 seans AT uygulandı. KT grubundaki bireylere ise, AT'ye ilaveten kognitif task verildi. Tüm katılımcıların üst ekstremite fonksiyonelliği Fugl-Meyer Üst Ektremite Motor Değerlendirmesi (FMA), kognitif açıdan Mini-Mental Durum Testi (MMDT), spastisite seviyesi Mofiye Ashworth Ölçeği (MAS), günlük yaşam aktiviteleri Barthel Günlük Yaşam Aktivite Ölçeği (BDI), yaşam kaliteleri İnmeye Özgü Yaşam Kalitesi Ölçeği (SSQOL) ve depresyon seviyeleri Beck Depresyon Ölçeği (BDÖ) ile çalışmanın başlangıcında ve bitiminde değerlendirildi. Grup içi değerlendirmelerde her iki grupta da FMA, MMDT, BDI, SSQOL, BDÖ ölçeklerinde istatiksel olarak anlamlı bir iyileşme bulundu (p<0.05). Gruplar arası değerlendirmelerde tedavi sonrasında MMDT'nde grup*zaman değerlendirmesinde BDI'da AT+KT grubu lehine istatiksel olarak anlamlı bir fark bulundu (p<0.05). Çalışmamızın sonucuna göre inmeli bireylerde ev temelli telerehabilitasyon yöntemiyle uygulanan kognitif tasklı ayna terapisi bireylerin genel kognitif durumunda iyileşmeye ve günlük yaşam aktivitelerinde bağımsızlığın artmasına neden oldu.
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    Manuel tedavi ve nöromusküler egzersiz programının sakroiliak eklem disfonksiyonu kaynaklı bel ağrısı ve mobilite üzerine etkilerini araştırma
    (İstanbul Medipol Üniversitesi, Sağlık Bilimleri Enstitüsü, 2022) Çelebi, Atalay; Hajebrahimi, Farzin
    Sakroiliak eklem disfonksiyon sendromu (SİEDS) yaygın olarak tartışılan bir bel ağrısı kaynağıdır. Mobilizasyon, manipülasyonlar ve egzersizler sakroiliak eklem disfonksiyonunda pozisyonel bozukluğu düzeltmekte sıklıkla kullanılmaktadır. Bu çalışmanın amacı SİEDS olan hastalarda konvansiyonel tedavinin, mobilizasyon tekniklerinin ve nöromusküler egzersiz programının ağrı, fonksiyonellik ve spinal mobiliteye etkisini araştırmaktır. Çalışmaya yaş aralığı 18-60 arasında SİEDS tanılı 45 birey dahil edildi ve katılımcılar randomize olarak Mobilizasyon Grubu(n=30), Nöromüsküler Egzersiz Grubu(n=30) ve Kontrol Grubu(n=30) olarak üç gruba ayrıldı. 30 dakikalık seanslar şeklinde, haftada 3 kez olmak üzere 4 hafta boyunca toplam 12 seans mobilizasyon grubuna manuel terapi teknikleri, nöromüsküler egzersiz grubuna egzersiz programı, kontrol grubuna konvansiyonel tedavi programı uygulandı. Bireyler tedavi önce ve sonrasında ağrı için Görsel Analog Skalası (GAS) ile, fonksiyonellik Schober testi (ST), engellik için ise Oswestry Engellilik Anketi (OEA) ile değerlendirildi. Grup içi değerlendirmelerde tüm gruplarda GAS, ST, OEA skorlarında anlamlı iyileşme bulundu (p<0.05). Gruplar arası değerlendirmelerde GAS, ST, OEA skorlarında mobilizasyon grubu lehine anlamlı fark bulundu (p<0.05). SİEDS'li bireylerde konvansiyonel tedavi programı, mobilizasyon teknikleri ve nöromusküler egzersiz programi ağrı, fonksiyonellik ve spinal mobiliteyi iyileştirmede etkili olabilir. Mobilizasyon teknikleri SİEDS'li bireylerin ağrı, fonksiyonellik ve spinal mobiliteleri üzerinde konvansiyonel tedavi programi ve nöromusküler egzersiz programina göre daha etkili olabilir.
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    Supervised exercises versus telerehabilitation. Benefits for persons with multiple sclerosis
    (Wiley, 2021) Tarakçı, Ela; Tarakçı, Devrim; Hajebrahimi, Farzin; Budak, Miray
    Objectives The purpose of this study was to investigate the effectiveness of structured telerehabilitation on fatigue, health status, quality of life (QoL), and activities of daily living (ADL) and compare the possible effects with structured supervised exercise programs in patients with Multiple Sclerosis. Materials and methods This study was a randomized, single-blind trial. Thirty patients with relapsing-remitting Multiple Sclerosis were included in the study and randomly divided into two groups; structured supervised exercise group (Group 1) and telerehabilitation group (Group 2). Group 1 (n = 15) completed a 12 week structured supervised exercise program. Group 2 (n = 15) completed a 12 week structured home-based exercise program. Patients were evaluated with functional independence measure (FIM), first section of Nottingham Health Profile (NHP-I), fatigue severity scale (FSS), and quality of life scale (QoLS) before and after the intervention. Results Significant differences were found in all parameters in both groups after the treatment (p < .05). No significant difference was found between groups regarding FIM-total, FIM-motor, FIM-cognitive, NHP sub-parameters, and QoLS (p > .05). Between-group differences revealed a significant difference in FSS and NHP total in favor of Group 1 (p < .05). Conclusion A structured home-based exercise program can be an alternative to supervised exercises with no side effects in patients with multiple sclerosis. Home-based rehabilitation exercises that are checked and controlled through telerehabilitation can help patients improve their health-related QoL and ADL. However, supervised exercises can be more beneficial regarding the fatigue and health profile compared to the home-based exercises.
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    The effect of leap motion controller based exergame therapy on hand function, cognitive function and quality of life in older adults. A randomised trial
    (Pacini Editore S.p.A./AU-CNS, 2023) Akdemir, Simay; Tarakçı, Devrim; Budak, Miray; Hajebrahimi, Farzin
    Objective. To evaluate the effect of leap motion controller based exergame therapy (LMCBET) on hand function, cognitive function and quality of life (QoL) in older adults. Design. A parallel, double-blind trial with participants allocated (1:1) to one of two groups as the structured exercise (SE) and LMCBET. Setting. The study was conducted in “Barınyurt Nursing Home and Elderly Care Center” in Istanbul. Participants. Thirty-two older adults who had adequate hand function, ability to follow commands, 24 points or more in the mini mental state examination (MMSE) were included and 30 were analyzed. Interventions. SE Group performed a Structured Hand Exercise program while LMCBET group performed “ErgoActive’’ and “HandROM” exercise apps focusing on hand exercises and fine motor skills along 30-45 minute sessions, 2 days a week, over 8 weeks. Main outcome measures. Participants were evaluated with box and block test (BBT), Purdue Pegboard test (PPT), hand dynamometer, Duruöz hand index (DHI), stroop test (ST), digit span test (DST), and World Health Organization QoL instrument-older adults module (WHOQOL-OLD) at the beginning (T0), at 8 (T1), and 16 (T2) weeks after the study started. Results. There were significant differences in BBT, PPT, DHI, and WHOQOL-OLD in the SE group (p < 0.05). BBT, right, left, couple, total scores of PPT, DHI and WHOQOL-OLD were found significant in the LMCBET group (p < 0.05). In Time*Group evaluations, there were no differences (p > 0.05). Conclusions. SE and LMCBET were effective on hand function and QoL in healthy older adults.
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    The effects of exercise on pain and depression in mothers of disabled children who suffer from back pain
    (BMJ Publishing Group, 2019) Uzun, Nejla; Hajebrahimi, Farzin; Tarakçı, Devrim; Tarakçı, Ela
    Background:The rate of back pain prevalence and its subsequent nega-tive psychological effects is quite high in mothers of disabled children.Family caregivers of children with a disability demonstrate higher degreesof chronic conditions and are more likely to engage in health risk behav-iors (1, 2).Objectives:The purpose of this study was to investigate the effects ofhome exercise programs on mothers’back pain, relevant functional influ-ence and the depression level (3).Methods:Forty-two mothers aged 35,71±6,53 were included in this studywhom children were diagnoses with cerebral palsy. Back pain level ofthe mothers was measured with Visual Analogue Scale (VAS), relevantfunctional disability was measured with Oswestry Disability index anddepression level was measured with Beck Depression Scale. Disabilitylevel of their children was measured with Gross Motor Function Classifi-cation System (GMFCS). Following the assessments, a home exerciseprogram consisting of Dynamic Lumbar Stabilization Exercises was givento mothers. They were asked to perform the exercises for three monthsand exercises were checked once in a month.Results:GMFCS average of the children was 3,35±1,57. There was asignificant difference in the pain level (VAS) changed from 4,90±2,67 to3,21±2,50 after the exercise (p=0,000). The difference between theOswestry Disability Index score before (13,92±8,32) and after the exercise(10,76±8.54) was statistically significant (p=0,001). Also there was a sig-nificant difference in the Beck Depression Scale score decreased from25,16±9,46 to 12,76±7,50 (p=0,009).Conclusion:Mothers with disabled children complain about back pain dur-ing activities such as caregiving their children (4). This study reveals thatback pain, relevant functional influence and depression could be reducedin mothers by perform recommended exercises regularly.
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    Virtual reality training helpful in motor and cognition in corticobasal syndrome: A case report PET study
    (Karger, 2020) Hajebrahimi, Farzin; Çakır, Tansel; Hanoğlu, Lütfü
    Corticobasal syndrome (CBS) is a rare progressive neurodegenerative disease characterized by a combination of asymmetric motor symptoms and non-motor symptoms. CBS is poorly responsive to levodopa. Non-pharmacological strategies have been found to be useful as components of a multidisciplinary therapeutic approach for patients with CBS. The purpose of this study was to investigate the effects of virtual reality training in addressing symptoms of CBS. A 64-year-old man was clinically diagnosed as CBS one year after the onset of complaints. Positron emission tomography (PET) scan showed asymmetrical hypometabolism in the right thalamus and basal ganglia. The patient was evaluated for balance, gait, mobility, and cognition 1 week before, 1 week after, and 1 year after 6 weeks of training, 3 times weekly (18 sessions in total). All clinical outcomes and PET result had improved after the intervention; cognition and balance were maintained after 1 year. Additionally, the asymmetric hypometabolism, which had been detectable on the PET scan, became normal, and a relative improvement was noted in the visual evaluation of cortical involvement. Virtual reality may address different aspects of motor and cognition and possibly brain metabolic changes that can affect the course of the disease in patients with CBS.

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