Yazar "Aras, Adem Bozkurt" seçeneğine göre listele

Listeleniyor 1 - 8 / 8
  • Küçük Resim
    Öğe
    Chronic spinal epidural hematoma in an adult
    (Tıp Araştırmaları Derneği, 2015) Tokmak, Mehmet; Aras, Adem Bozkurt; Altıok, İnci Baltepe; Güven, Mustafa; Çoşar, Murat
    Spinal epidural hematoma (SEH) causing neurological deficit is a rare clinical entity. It may have either traumatic origin or it may occur spontaneously. Majority of the reported cases of SEH had nontraumatic causes and most of them were in the acute stage. Early chronic traumatic SEH in an adult is very rare and its prompt diagnosis with magnetic resonance imaging (MRI) is crucial for the accurate management of the patient. Our case was 56 year-old man presented at our neurosurgery clinic with a complaint of progressive burning pain, weakness, paresthesia over the left leg and hypoesthesia over the pelvic region. In this report, we presented a postraumatic lumbar SEH which is a unique presentation of chronic traumatic SEH because of long time interval between the trauma and beginning of the symptoms.
  • Küçük Resim
    Öğe
    Comparison of anterior cervical discectomy fusion techniques: Bladed and non bladed PEEK cages
    (Turkish Neurosurgical Soc, 2016) Güven, Mustafa; Çoşar, Murat; Alkan, Bahadır; Aras, Adem Bozkurt; Akman, Tarık; Şafak, Özbey; Karaarslan, Öznur; Ceylan, Davut; Tokmak, Mehmet
    AIM: The aim of this study is to compare the different types of fusion materials known as PEEK cages used during anterior cervical discectomy (ACD) surgery. MATERIAL and METHODS: A total of 67 patients were operated and evaluated retrospectively under two groups (group A: 35 PEEK cage patients, group B: 32 bladed PEEK cage patients) between 2009 and 2013. Preoperative and postoperative (postoperative first day, postoperative 1st, 3rd and 12-24th mo) images were obtained. The cervical disc heights, cervical and segmental lordotic angles of the operated levels were calculated. Pain assessment was performed and fusion rates were also compared. Mann-Whitney U test was applied to compare the outcomes. RESULTS: The pain scores (especially for arm pain) were decreased significantly in both groups after surgery regardless of the type of operation technique (P<0.05). There were no significant differences between both groups at the disc height measurements of operated levels in postoperative periods (P>0.05). In addition to these; there was no significant difference between both groups of segmental and cervical lordodic angles in postoperative periods (P>0.05). There was no statistically significant difference between the fusion rates and pain scores of both groups (P>0.05). CONCLUSION: The PEEK cage and bladed PEEK cages can be used safely to obtain fusion after ACD.
  • Küçük Resim
    Öğe
    Effect of using high-speed drill in anterior cervical discectomy and fusion
    (Turkish Neurosurgical Soc, 2016) Güven, Mustafa; Ceylan, Davut; Aras, Adem Bozkurt; Akbal, Ayla; Gökmen, Ferhat; Reşorlu, Hatice; Alkan, Bahadır; Tokmak, Mehmet; Coşar, Murat
    AIM: The objective of this study was to investigate the effect of using 2 different surgical techniques (curette or high-speed drill) in anterior cervical discectomy surgery on the healing of cases. MATERIAL and METHODS: Fifty-four operated cervical disc hernia cases were retrospectively examined in 2 groups. Discectomy and osteophytectomy were carried out in Group A by using a high-speed drill, while a curette was used for group B. Preoperative and postoperative computerized tomography and direct radiography were performed. Cervical disc height, cervical and segmental lordotic angles were calculated. The visual analogue scale and Odom's criteria were used in the assessment of pain and clinical healing. The fusion ratio of both groups was compared. The Mann-Whitney U test was used to compare data from the groups. RESULTS: Satisfactory results were obtained in the groups where high-speed drill and curette were used. Independently from the surgical technique, pain scores were significantly reduced in both groups after surgery. No radiologically significant differences were identified between the two groups within the postoperative period. CONCLUSION: Either high-speed drill or curette can be chosen for the osteophytectomy and discectomy stages of anterior cervical discectomy operations.
  • Küçük Resim
    Öğe
    Evaluation of the association between matrix metalloproteinase 11 and intervertebral disc disease
    (Turkish Neurosurgical Society, 2016) Aras, Adem Bozkurt; Güven, Mustafa; Balak, Naci; Ayan, Erdoğan; Uyar Bozkurt, Suheyla; Elmacı, İlhan
    AIM: The intervertebral disc starts to degenerate when a human being begins to stand and learn to walk. It is known that many extrinsic, intrinsic and genetic factors play a role in disc degeneration. In this study, we examined whether the matrix metalloproteinase 11 might be associated with intervertebral disc degeneration. MATERIAL and METHODS: Fifty-six patients with lumbar disc herniations who were operated at Gortepe Education and Research Hospital, Neurosurgery Clinic between September 2008 and December 2009 were prospectively reviewed. History and complaints were obtained from the case reports. Neuroradiological evaluation was performed with magnetic resonance imaging. Surgical findings of cases were reported in the operation notes. Microscopic posterior hemipartial laminectomy and discectomy were performed in all cases. Degenerated herniated disc material of all cases extracted during surgery was evaluated with immunohistochemical staining in Marmara University, Institute of Neurological Sciences, Pathology Laboratory. RESULTS: Comparing the immunohistochemical staining of cases who were 50 years or younger and cases who were over 50 years old, statistical significance was determined. CONCLUSION: Matrix metalloproteinase 11 has a role in degenerating intervertebral disc disease, but it is not the only factor. Matrix metalloproteinase 11 might be a genetic factor in young-middle aged patients.
  • Küçük Resim
    Öğe
    Management of type II odontoid fractures for osteoporotic bone structure: Preliminary report
    (Turkish Neurosurgical Society, 2015) Coşar, Murat; Özer, Ali Fahir; Alkan, Bahadır; Güven, Mustafa; Akman, Tarık; Aras, Adem Bozkurt; Ceylan, Davut; Tokmak, Mehmet
    AIM: Anterior transodontoid screw fixation technique is generally chosen for the management of type II odontoid fractures. The nonunion of type II odontoid fractures is still a major problem especially in elderly and osteoporotic patients. Eleven osteoporotic type II odontoid fracured patients were presented in this article. MATERIAL and METHODS: We have divided 11 patients in two groups as classical and Ozer's technique.We have also compared (radiologically and clinically) the classical anterior transodontoid screw fixation (group II: 6 cases) and Ozer's transodontoid screw fixation technique (group I: 5 cases) retrospectively. RESULTS: There was no difference regaring the clinical features of the groups. However, the radiological results showed 100% fusion for Ozer's screw fixation technique and 83% fusion for the classical screw fixation technique. CONCLUSION; In conclusion, we suggest that Ozer's technique may help to increase the fusion capacity for osteoporotic type II odontoid fractures.
  • Küçük Resim
    Öğe
    Spontaneous regression of lumbar disc herniation after weight loss: Case report
    (Turkish Neurosurgical Society, 2015) Tokmak, Mehmet; Baltepe Altıok, İnci; Güven, Mustafa; Aras, Adem Bozkurt; Coşar, Murat
    Diagnosis, treatment, and surgery for lumbar disc herniations have existed for over a century. However, during the last three decades, there have been many new developments in imaging techniques, surgical procedures, physical medicine, and rehabilitation. In light of this, the most effective and appropriate treatment is controversial. Spontaneous regression of sequestrated, extruded, or protruded disc herniation has often been reported in the literature, although it is still a rare phenomenon. After a thorough review of the literature, we did not find any case report about this phenomenon after weight loss. In this report, though, we present a recent case about spontaneous regression of extruded disc herniation following weight loss.
  • Küçük Resim
    Öğe
    The axon protective effects of syringic acid on ischemia/ereperfusion injury in a rat sciatic nerve model
    (Turkish Neurosurgical Society, 2017) Tokmak, Mehmet; Şehitoğlu, Müserref Hilal; Yüksel, Yasemin; Güven, Mustafa; Akman, Tarık; Aras, Adem Bozkurt; Yaka, Umut; Gömleksiz, Cengiz; Albayrak, Serdar Baki; Coşar, Murat
    AIM: In the relevant literature, there is no experimental study that investigated the axon protective effects of syringic acid- a polyphenol compound- with an anti-oxidant capacity on ischemia/reperfusion injury. MATERIAL and METHODS: The rats were randomly divided into four groups: Control group (no medication or surgical procedure), Sham group, Syringic acid group, and Methyprednisolone (MP) Group. lschemia was achieved by abdominal aorta clamping and all animals were sacrificed 24 hours after ischemia. Harvested sciatic nerve segments were investigated histopathologically and for tissue biochemistry. RESULTS: lschemic fiber degeneration scores were found significantly lower in syringic acid and MP groups than sham group. Additionally, apoptosis-related cysteine peptidase caspase-3 immunostaining scores were lower in syringic acid and MP groups. Biochemically, superoxide dismutase and nuclear respiratory factor 1 values were significantly higher in syringic acid group compared to those of control and sham groups while malondialdehyde levels were significantly lower in the syringic acid group. CONCLUSION: Syringic acid reduces oxidative stress and axonal degeneration in rat sciatic nerve after ischemia/reperfusion injury. Therefore, syringic acid may play a role in the treatment of peripheral nerve injuries due to ischemia/reperfusion.
  • Küçük Resim
    Öğe
    The effect of coumaric acid on ischemia-reperfusion injury of sciatic nerve in rats
    (Springer/Plenum Publishers, 2015) Güven, Mustafa; Yüksel, Yasemin; Şehitoğlu, Müşerref Hilal; Tokmak, Mehmet; Aras, Adem Bozkurt; Akman, Tarık; Gölge, Umut Hatay; Göksel, Ferdi; Karavelioğlu, Ergun; Coşar, Murat
    The aim of the study was to determine the effect of coumaric acid on sciatic nerve ischemia/reperfusion (SNI) injury in rats. The rats were randomly divided into four groups: control group (no medication or surgical procedure), SNI group, SNI + coumaric acid (CA) group, and SNI + methylprednisolone (MP) group. Ischemia was achieved by abdominal aorta clamping, and all animals were sacrificed 24 h after ischemia. Harvested sciatic nerve segments were investigated histopathologically and for tissue biochemistry. A significant decrease in MDA, an increase in NRF1 levels, and increase in SOD activity were observed in the groups which received coumaric acid and methylprednisolone when compared to the corresponding untreated group (p < 0.05). Ischemic fiber degeneration significantly reduced in the SNI + CA and SNI + MP groups, especially in the SNI + MP group, compared to the SNI group (p < 0.05). Beta amyloid protein expressions were significantly decreased in the SNI + CA group compared to the SNI group (p < 0.05). Our study revealed that coumaric acid treatment after ischemia/reperfusion in rat sciatic nerves reduced oxidative stress and axonal degeneration. Therefore, coumaric acid may play a role in the treatment of peripheral nerve injuries due to ischemia/reperfusion.