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    Management of granulosa cell ovarian tumors: 10-year experience in a tertiary center
    (Galenos Publishing House, 2022) Karakaş, Sema; Önder, Ayşe Büşra; Demirayak, Gökhan; Comba, Cihan; Avşar, Selim; Akay, Burcu; Süzen Çaypınar, Sema; Özdemir, Aykut
    Objective: Granulosa cell tumors (GCT) arise from the mesenchymal cells and sex cords of the ovaries and can be observed in women of all age groups. This study presented our 10 year-long gynecology oncology experience on the clinical course and outcome of GCT cases. Methods: Thirty-one patients who were operated due to suspicious adnexal masses in our hospital between January 2011 and January 2018 and whose final pathology report confirmed the diagnosis of GCT was included in the study. The data of the patients were evaluated. Preoperative ultrasound findings and serum tumor marker results are noted. Results: Twenty-nine (94%) patients were diagnosed with AGCS and only two (6%) patients were diagnosed with JGCS. The mean age of the study population was 47.74 14.47 years and the mean body mass index was 32.51 7.1. Most patients presented with heavy menstrual bleeding (29%). 48.4% of the patients underwent hysterectomy with bilateral salpingo-oophorectomy, and complete lymph-node dissection, whereas 22.6% of them had hysterectomy with bilateral salpingo-oophorectomy, and 29% of them had oophorectomy only. Three patients (9.3%) had a disease recurrence. The overall survival was 54.4 29.3 months and disease free survival was 49.6 24.2 months. Conclusion: The most important predictor of survival among patients with GCT is a disease stage at the time of initial diagnosis. Long-term surveillance, including routine clinical follow-up and evaluation of tumor markers is mandatory.
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    The effect of informing the patient about the procedure with video imaging before office hysteroscopy on pain
    (John Wiley and Sons Inc, 2023) Çallıoğlu, Nihal; Kanza Gül, Derya; Özer Aslan, İlke; Fendal Tunca, Aysun; Başlı Kasım, Kardelen; Akay, Burcu; Uysal, Elif; Ekin, Murat
    Objective: To evaluate the effect of informing patients undergoing diagnostic office hysteroscopy via a video 24 h before the procedure and determine the changes in pain scores, channel transit time, the degree of difficulty of the procedure, and physiological parameters. Design: Single-blind randomized controlled trial. Setting: The study was conducted between September 1, 2021 and April 1, 2022 at the University of Health Sciences Bakirkoy Dr. Sadi Konuk Training and Research Hospital. Participants: A total of 134 patients aged 18-65 years who needed diagnostic office hysteroscopy. Interventions: Participants were randomized into two groups, the standard information group (Group 1: controls), and the video information + standard information group (Group 2). After office hysteroscopy, a visual analog scale (VAS) and Likert scale were used to assess pain and the degree of difficulty of the procedure, respectively. Physiological parameters were evaluated before and after the procedure. Main Outcome Measure: To determine the effect of video-based multimedia information administered 24 h before office hysteroscopy on post-procedure pain. Results: The mean VAS score of the group that watched the training video (3.02 +/- 1.88) was significantly lower than the control group (4.72 +/- 2.54) who did not watch the training video (p < 0.001). The mean cervical channel transit time in seconds (sec) during the procedure was found to be significantly higher in the control group (21.57 +/- 15.10 s) than in the video-watching group (p = 0.011). There was no significant difference between the groups in terms of physiological parameters and the degree of ease of the procedure. Conclusion: Our study has shown that informing patients in a pre-procedure video is an effective approach that shortens the duration of the channel transit time and reduces pain.