Yazar "Akan, Serkan" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Reliability and validity analysis of Turkish version of the symptoms of lower urinary tract dysfunction research network symptom index-10 questionnaire
    (2024) Akan, Serkan; Tavukçu, Hasan Hüseyin; Çulpan, Meftun; Cella, David
    INTRODUCTION: To evaluate the validity and reliability of the Turkish version of the Symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index-10 (LURN SI-10). MATERIALS AND METHODS: In this, single-centre study, patients between 18 and 65 years old, who were suffering from lower urinary tract symptoms (LUTS) without any known urinary tract disease and on no medication, were enrolled. The control group consisted of participants, who were admitted to our clinic suffering from any complaint except LUTS and met all of the other inclusion and exclusion criteria. Participants' demographics such as age, sex, and level of education were recorded. The Turkish version of the LURN SI-10, International Prostate Symptom Score (IPSS) and Overactive Bladder Questionnaire (OAB-V8) were administered to all participants. Construct validity was evaluated by confirmatory factor analysis and concurrent validity was evaluated with correlations to similar measures. Internal consistency (Cronbach's alpha) was used to establish the scale's internal consistency reliability. RESULTS: A total of 164 participants were included in the final analysis. Of those, 57% were male. The individuals were identified as being in the "patient group" (n = 86) and a "control group" (n = 78). The mean age was 48.24 ± 14.30 years. The median total LURN SI-10 scores of patient group and control group were 12.0 (9-18.25) and 4.0 (2.75-6), respectively. The LURN SI-10 questionnaire showed a high correlation with the IPSS and the OAB-V8 questionnaires (r: 0.761; p: 0.001; r: 0.737; p: 0.001, respectively) in concurrent validity analysis. Cronbach's alpha coefficient of the LURN SI-10 was 0.850. CONCLUSIONS: This promising measurement tool can be used to evaluate LUTS in Turkish women and men. Further studies should be conducted to assess the clinical usefulness of this questionnaire.
  • Küçük Resim
    Öğe
    The cancer of the bladder risk assessment score and mortality-survival relationship among patients who have undergone radical cystectomy in the Turkish urooncology association database
    (2024) Tavukçu, Hasan Hüseyin; Tinay, İlker; İzol, Volkan; Baltacı, Sümer; Teke, Kerem; Süer, Evren; Yücetaş, Uğur; Yazıcı, Sertaç; Akan, Serkan
    Objective: The Cancer of the Bladder Risk Assessment (COBRA) score is a practical method that can be used to predict survival in patients who have undergone radical cystectomy (RC). We aimed to evaluate COBRA scores in our patient group. Materials and Methods: Patients were classified according to tumor stage and lymph node (TLN) involvement; mortality rates and survival were analyzed according to both the TLN classification and COBRA score from the Turkish Urooncology Association database. The chi-square test and Fisher-Freeman-Halton Exact chi-square test were used to compare qualitative data as well as descriptive statistical methods. Cox regression analysis was used for multivariate analysis. Kaplan- Meier and log-rank tests were used for survival analysis. Results: There was a statistically significant difference between the COBRA scores and survival rates in terms of cancer-specific mortality according to TLN classification (p=0.000; p<0.05). A COBRA score of 6 was associated with a lower mortality rate than a COBRA score of 5. In the Cox regression analysis of cancer-related death, a one-unit increase in the COBRA score increased the cancer-related death rate 1.54-fold [hazard ratio (HR)=1.540; 95% confidence interval (CI)=1.402-1.691] (p<0.05). When the COBRA score was compared to 0, the highest risk was observed for COBRA 5. If the COBRA score was 5, the risk of cancer- related death increased 14.63 times (HR=14.627; 95% CI=7.041-30.385) (p<0.05). If the COBRA score was 6, the risk of cancer-related death increased by 11.54 times (HR=11.547; 95% CI=5.270-25.278) (p<0.05). Conclusion: The COBRA score increased, the prognosis worsened, and our results are consistent with the first validated study.