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  • Küçük Resim
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    Comparison of breast cancer patients over the age of 70 and under the age of 35
    (Turkish Geriatrics Society, 2023) Akan, Arzu; Günay, Semra; Bademci, Refik; Gürdal, Necla; Güven, Merve Nur; Yalçın, Orhan
    İntroduction: Although breast cancer is a type of cancer that is mainly seen in advanced ages, its incidence is increasing in early ages in developing countries. While advanced age may create limitations in treatment due to the person's functional capacity and low life expectancy, treatments may be exaggerated at a young age due to the long-life expectancy and expectations from life. In this study, we aimed to examine possible differences in approach in two different age groups diagnosed with breast cancer. Materials and Methods: The retrospective study included 123 patients over the age of 70 or under 35 who applied to our hospital's breast surgery outpatient clinic between 2016 and 2021 and were diagnosed with breast cancer. The patients' complaints at the outpatient clinic, the histopathological features of the tumor, and the treatments applied were compared. Results: 64 (52%) of the patients included in the study were over 70 years old, and 59 (47%) were under 35 years old. Patients in both groups were applied to the outpatient clinic with a palpable mass. Histopathologically, invasive ductal cancer constituted the majority in both groups. While the elderly patients were lower grade and Estrogen receptor-positive, the younger patients were high grade, Estrogen receptor negative, and mostly triple negative. Conclusions: Regardless of age, breast cancer is a cancer type that can have better results with early diagnosis. While making the treatment decision the decision should be made according to the characteristics of the tumor, comorbidity, and life expectancy, regardless of the patient's age.
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    Rectum cancer: The effects of perioperative outcomes of patients as long-term prognostic factor
    (2019) Bademci, Refik; Öndeş Bayar, Özlem; Tabak Dinçer, Selvi; Akan, Arzu; Camcı, Cemalettin; Eryavuz, M. Yavuz
    Aim: After cancer treatment, patients and clinicians expect accurate prediction of long-term prognosis. The aim of this study was to determine which perioperative factors that may also be useful in determining long-term prognosis. Material and Methods: The data of rectum cancer patients operated on between 1998 and 2006 were retrospectively compared in respect of clinicopathological and operative results, and long-term survival. Survival was calculated using a Kaplan-Meier method. Data thought to be associated with survival were subjected to univariate analysis followed by Cox proportion regression. Results: A total of 348 patients were included in the study. The mean age was 56 (±12) years in patients and 195 (56%) were male patients. After retrospective evaluation of the database, the mean duration of disease-free survival was 54 (±50) months and the mean duration of life was 60 (±48) months. There was no statistically significant correlation between gender, surgical procedure, histopathologic type of tumor, T level of the tumor, stage of the patient, ca 19-9 and mean life span. Grade, lymph node status and CEA were statistically correlated with survival time. Conclusion: We have demonstrated that grade, lymph node status and CEA are associated with long-term survival. These clinical factors are suitable to provide a good clinical guide to prognosis.
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    The use of dermal automesh for incidental hernia repair in abdominoplasty: Clinical, biochemical, and radiological results
    (Informa Healthcare, 2015) Özkaya Mutlu, Özay; Egemen, Onur; Akan, Arzu; Akan, Mithat; Karahangil, Mehmet; Filinte, Gaye; Bozdağ, Ergün; Sünbüloğlu, Emin; Kurtul, Hülya
    Abdominal wall hernias are often diagnosed on clinical examination or encountered intraoperatively during an abdominoplasty. The aim of this study is to evaluate the long-term results of the use of dermal automesh for the repair of incidental hernias during abdominoplasty operations, and to perform a comparative analysis of the biomechanical strengths of dermal automesh vs biological tissue graft. Between 2008 - 2012, dermal automesh was used in 12 patients for hernia repair. After repair of hernia, dermal automesh was applied over the repaired area in an onlay fashion. Postoperative follow-up was performed by physical examination and magnetic resonance imaging (MRI) of the abdominal wall. Biomechanical test was performed with prepared samples from excised abdominal panniculus for tensile strength and yield power. Mean age was 45 years (range = 36 - 54 years). Total follow-up was 26 (14 - 52) months. MRI studies showed that there were no hernias or defects of the anterior abdominal wall. The tensile strength of the dermal mesh was measured as 15.9 +/- 6.0 Mpa (6.4 - 24.5), maximum load before yield measured 680 +/- 175.2 N (336.0 - 856.0). In conclusion, dermal automesh is a useful option for surgeons who encounter undiagnosed hernias during abdominoplasties.