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dc.contributor.authorSadri, Sevil
dc.contributor.authorPolat, Burcu
dc.contributor.authorBalık Aydın, Berrin
dc.contributor.authorKoçar, Hakan
dc.contributor.authorGemici, Aliihsan
dc.contributor.authorBeköz, Hüseyin Saffet
dc.contributor.authorSevindik, Ömür Gökmen
dc.contributor.authorSargın, Fatma Deniz
dc.date.accessioned2022-08-22T07:25:04Z
dc.date.available2022-08-22T07:25:04Z
dc.date.issued2022en_US
dc.identifier.citationSadri, S., Polat, B., Balık Aydın, B., Koçar, H., Gemici, A., Beköz, H. S. ... Sargın, F. D. (2022). Evaluation of neurological imaging after hematopoietic stem cell transplantation in adults. Eastern Journal of Medicine, 27(3), 437-445. http://doi.org/10.5505/ejm.2022.54765en_US
dc.identifier.issn1301-0883
dc.identifier.urihttp://doi.org/10.5505/ejm.2022.54765
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9663
dc.description.abstractTo investigate the risk factors for, and the incidence of, structural abnormalities in brain imaging among hematopoetic stem cell transplant (HSCT) patients and to correlate these findings with physical examinations. This study retrospectively reviewed all post-HSCT brain imaging taken in the researchers’ center between 2014 and 2020. 87 of 627 transplant patients were imaged. 34.5% (n = 30) were female. Age at transplant ranged from 18 to 74 years (median: 45). The most common malignancies were acute myeloid leukemia (AML; n = 21; 24.1%), 51 (58.6%) patients received allogeneic transplantation, and 36 (41.4%) received autologous transplantation. The imaging techniques were dispersed as follows: magnetic resonance imaging (MRI): 83.9% (n = 73), brain computed tomography (CT): 37.9% (n = 33), diffusion MRI: 19.5% (n = 17). 39.1% of the radiological images were normal; 20.7% showed disease recurrence; and 14.9% detected ischemic gliotic lesions. According to the imaging results, there was a statistically s ignificant difference between age values (p = 0.013). Patients with PRES were younger than those with no pathologies in their imaging, while patients with infarcts and ischemic gliotic lesions were older than those with normal imaging (p = 0.001). Patien ts with disease recurrence were older than those with PRES but younger than those with infarctions (p = 0.001). Neurological complications are not uncommon in transplant cases. In managing transplantations, it should be remembered that the presence of radiologically positive findings, especially positives for cerebrovascular complications, can significantly reduce survival.en_US
dc.language.isoengen_US
dc.publisherYüzüncü Yıl University Faculty of Medicineen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectBrain Imagingen_US
dc.subjectNeurological Complicationsen_US
dc.subjectHematopoietic Stem Cell Transplantationen_US
dc.subjectCerebrova Scular Complicationsen_US
dc.titleEvaluation of neurological imaging after hematopoietic stem cell transplantation in adultsen_US
dc.typearticleen_US
dc.relation.ispartofEastern Journal of Medicineen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalıen_US
dc.authorid0000-0002-6315-9620en_US
dc.authorid0000-0002-4104-8508en_US
dc.authorid0000-0001-6826-7818en_US
dc.authorid0000-0001-6869-7682en_US
dc.authorid0000-0002-3385-8359en_US
dc.authorid0000-0003-1237-8281en_US
dc.authorid0000-0001-9636-4113en_US
dc.authorid0000-0002-1077-8540en_US
dc.identifier.volume27en_US
dc.identifier.issue3en_US
dc.identifier.startpage437en_US
dc.identifier.endpage445en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.5505/ejm.2022.54765en_US
dc.institutionauthorSadri, Sevil
dc.institutionauthorPolat, Burcu
dc.institutionauthorBalık Aydın, Berrin
dc.institutionauthorKoçar, Hakan
dc.institutionauthorGemici, Aliihsan
dc.institutionauthorBeköz, Hüseyin Saffet
dc.institutionauthorSevindik, Ömür Gökmen
dc.institutionauthorSargın, Fatma Deniz
dc.identifier.scopus2-s2.0-85135566797en_US
dc.identifier.trdizinid1123902en_US
dc.identifier.scopusqualityQ4en_US


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