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dc.contributor.authorGüngören, Fatma Zeynep
dc.contributor.authorErol, Cengiz
dc.contributor.authorBilici, Ahmet
dc.contributor.authorDayangaç, Murat
dc.contributor.authorŞeker, Mehmet
dc.contributor.authorÖlmez, Ömer Fatih
dc.contributor.authorYaprak, Onur
dc.contributor.authorYıldız, Özcan
dc.contributor.authorÖncel, Mustafa
dc.date.accessioned2022-05-06T07:39:31Z
dc.date.available2022-05-06T07:39:31Z
dc.date.issued2022en_US
dc.identifier.citationGüngören, F. Z., Erol, C., Bilici, A., Dayangaç, M., Şeker, M., Ölmez, Ö. F. ... Öncel, M. (2022). The comparison of local tumor control after microwave ablation, surgical resection and combined treatment for colorectal liver metastases. Journal of Mind and Medical Sciences, 9(1), 125-132. https://doi.org/10.22543/7674.91.P125132en_US
dc.identifier.issn2392-7674
dc.identifier.urihttps://doi.org/10.22543/7674.91.P125132
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9406
dc.description.abstractAim. We aimed to compare the local therapeutic efficiency of microwave ablation (MWA), surgical resection, and combined treatment, assess the outcomes, and identify predictive factors for local treatment response in colorectal liver metastases (CLMs). Methods. From March 2013 to September 2019, a total of 54 patients with 302 CLMs were enrolled in this retrospective study. Eleven patients (20.4%) were treated with MWA, 9 patients (16.7%) with surgery, and 34 patients (63%) with the combined method. Univariate and multivariate analyses were performed to investigate overall survival (OS) and hepatic progression-free survival (HPFS) using the Cox proportional hazard regression model. The logistic regression analysis was used to identify the predictive factors for the local treatment response. Results. Total treatment response was achieved in 46.3% (n=25) of the patients. Local tumor progression was seen in 7.4% (n=4) of the patients, and the rate of intrahepatic distal recurrence was 46.3% (n=25). There were no significant differences in HPFS and OS between the three groups (p=0.56 and 0.90, respectively). Younger age (<60), smaller (<= 2 cm) or fewer (<= 3) liver metastases, and wild-type RAS were predictive for higher rates of local treatment response (OR 0.22, 95% CI 0.15-0.93, p=0.04; OR 1.12, 95% CI 0.54-2.12, p=0.029; OR 1.37, 95% CI 0.97-2.37, p=0.035; OR 0.23, 95% CI 0.10-0.85, p=0.028, respectively). Conclusions. The results of this study reveal that the use of MWA, alone or combined with resection, may achieve high local treatment response and similar survival rates compared to patients undergoing resection, suggesting that MWA could potentially be preferred over surgical procedures.en_US
dc.language.isoengen_US
dc.publisherValpoScholar-Valparaiso Universityen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectColorectal Liver Metastasesen_US
dc.subjectMicrowave Ablationen_US
dc.subjectSurgical Resectionen_US
dc.subjectCombined Treatmenten_US
dc.subjectLocal Tumor Controlen_US
dc.titleThe comparison of local tumor control after microwave ablation, surgical resection and combined treatment for colorectal liver metastasesen_US
dc.typearticleen_US
dc.relation.ispartofJournal of Mind and Medical Sciencesen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalıen_US
dc.authorid0000-0003-3468-7712en_US
dc.authorid0000-0002-1240-7233en_US
dc.authorid0000-0002-6745-0159en_US
dc.authorid0000-0001-7934-7039en_US
dc.authorid0000-0003-1941-8290en_US
dc.authorid0000-0003-2342-073Xen_US
dc.authorid0000-0003-2357-5387en_US
dc.identifier.volume9en_US
dc.identifier.issue1en_US
dc.identifier.startpage125en_US
dc.identifier.endpage132en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.22543/7674.91.P125132en_US
dc.institutionauthorGüngören, Fatma Zeynep
dc.institutionauthorErol, Cengiz
dc.institutionauthorBilici, Ahmet
dc.institutionauthorDayangaç, Murat
dc.institutionauthorŞeker, Mehmet
dc.institutionauthorÖlmez, Ömer Fatih
dc.institutionauthorYaprak, Onur
dc.institutionauthorYıldız, Özcan
dc.institutionauthorÖncel, Mustafa
dc.identifier.wos000786532500015en_US


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