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dc.contributor.authorSulak, Muhammet Mustafa
dc.contributor.authorAhıskalıoğlu, Ali
dc.contributor.authorYayık, ‪Ahmet Murat
dc.contributor.authorKaradeniz, Erdem
dc.contributor.authorÇelik, Mine
dc.contributor.authorDemir, Ufuk
dc.contributor.authorArı, Muhammet Ali
dc.contributor.authorAlıcı, Hacı Ahmet
dc.date.accessioned2022-04-22T11:44:46Z
dc.date.available2022-04-22T11:44:46Z
dc.date.issued2022en_US
dc.identifier.citationSulak, M. M., Ahıskalıoğlu, A. Yayık, ‪A. M., Karadeniz, E., Çelik, M., Demir, U. ... Alıcı, H. A. (2022). The effect of ultrasound-guided serratus plane block on the quality of life in patients undergoing modified radical mastectomy and axillary lymph node dissection: A randomized controlled study. Anaesthesiology Intensive Therapy, 54(1), 48-55. https://doi.org/10.5114/ait.2022.114203en_US
dc.identifier.issn1731-2531
dc.identifier.urihttps://doi.org/10.5114/ait.2022.114203
dc.identifier.urihttps://hdl.handle.net/20.500.12511/9360
dc.description.abstractBACKGROUND: Modified radical mastectomy (MRM) and axillary lymph node dissection (AD) are the most commonly used surgical methods in breast cancer surgery, and they are characterized by moderate to severe pain. This study aimed to investigate the effect of ultrasound-guided serratus plane block (SPB) on postoperative acute and chronic pain in patients undergoing MRM and AD. METHODS: After ethical approval, 60 patients, aged between 18-65 years, ASA I-III, underwent unilateral MRM, and AD was assigned into 2 groups. The SPB group received ultrasound-guided SPB with 30 mL 0.25% bupivacaine, and the control group received 2 mL saline injection subcutaneously. Postoperative analgesia was performed with intravenous patient-controlled analgesia and dexketoprofen trometamol. Pain scores, opioid consumption, and rescue analgesic requirements were recorded. Chronic pain and quality of life were evaluated with the Numerical Rating Scale (NRS), short form-36 (SF-36), and painDETECT. RESULTS: Compared with the control group, the visual analogue scale scores were statistically lower in the SPB group during 4 postoperative hours in post-anaesthetic care unit PACU at 1st, 2nd (P < 0.001), and 4th hour (P = 0.014). Fentanyl consumption and rescue analgesics were lower in the SPB group than in the control group (0-4 h, P = 0.001; 4-8 h, 8-12 h, 24 h; total P < 0.001). The incidence of chronic pain was 11%, and there was no statistically significant difference between control and SPB groups in terms of SF-36, NRS, and painDETECT scores measured at the first and sixth months. CONCLUSIONS: SPB demonstrated superiority versus the control group concerning acute postoperative pain parameters. However, SPB had no influence on the quality of life and did not prevent chronic postmastectomy pain.en_US
dc.language.isoengen_US
dc.publisherNLM (Medline)en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChronic Painen_US
dc.subjectPre-Emptive Analgesiaen_US
dc.subjectSerratus Plan Blocken_US
dc.subjectModified Radical Mastectomyen_US
dc.titleThe effect of ultrasound-guided serratus plane block on the quality of life in patients undergoing modified radical mastectomy and axillary lymph node dissection: A randomized controlled studyen_US
dc.typearticleen_US
dc.relation.ispartofAnaesthesiology Intensive Therapyen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalıen_US
dc.authorid0000-0001-8057-5899en_US
dc.identifier.volume54en_US
dc.identifier.issue1en_US
dc.identifier.startpage48en_US
dc.identifier.endpage55en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.5114/ait.2022.114203en_US
dc.institutionauthorAlıcı, Hacı Ahmet
dc.identifier.wos000782842500009en_US
dc.identifier.scopus2-s2.0-85128001155en_US
dc.identifier.pmid35266378en_US
dc.identifier.scopusqualityQ2en_US


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