dc.contributor.author | Bayram, Dilara | |
dc.contributor.author | Aydın, Volkan | |
dc.contributor.author | Şanlı, Abdullah | |
dc.contributor.author | Abanoz, Mustafa Naci | |
dc.contributor.author | Sıbıç, Büşra | |
dc.contributor.author | Pala, Sedat | |
dc.contributor.author | Ataç, Ömer | |
dc.contributor.author | Akıcı, Ahmet | |
dc.date.accessioned | 2021-12-10T07:31:47Z | |
dc.date.available | 2021-12-10T07:31:47Z | |
dc.date.issued | 2021 | en_US |
dc.identifier.citation | Bayram, D., Aydın, V., Şanlı, A., Abanoz, M. N., Sıbıç, B., Pala, S. ... Akıcı, A. (2021). Comparison of paracetamol and diclofenac prescribing preferences for adults in primary care. Primary Health Care Research & Development, 22. https://dx.doi.org/10.1017/S1463423621000797 | en_US |
dc.identifier.issn | 1463-4236 | |
dc.identifier.issn | 1477-1128 | |
dc.identifier.uri | https://dx.doi.org/10.1017/S1463423621000797 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/8632 | |
dc.description.abstract | Introduction: The most frequently prescribed analgesic drugs in primary care centers in Turkey are diclofenac and paracetamol, respectively. In this study, we aimed to compare paracetamol-included prescriptions (PIP) and diclofenac-included prescriptions (DIP) generated for adult patients in primary care. Methods: In this cross-sectional study, PIPs (n = 280 488) and DIPs (n = 337 935) created for adults by systematic sampling among primary care physicians working in Istanbul in 2016 (n = 1431) were examined. The demographic characteristics, diagnoses, and additional drugs in PIPs and DIPs were compared. Results: Women constituted the majority in both groups (69.8% and 67.9%, respectively; P < 0.05), and mean age at PIP (52.6 +/- 18.8 years) was lower compared to DIP (56.3 +/- 16.1 years), (P < 0.05). In single-diagnosis prescriptions, 11 of the 15 most common diagnoses in PIP were respiratory tract infections (47.9%); three pain-related diagnoses formed 4.6% of all these prescriptions. In DIP, the number of pain-related diagnoses, mostly of musculoskeletal origin, was eight (28.5%); four diagnoses (7.8%) were upper respiratory tract infections. While hypertension was the third most common diagnosis in PIP (6.1%), it was ranked first in DIP (8.0%). The percentage of prescriptions with additional analgesic (14.0% versus 18.3%, P < 0.001), proton-pump inhibitor (13.8% versus 18.4%; P < 0.001), and antihypertensive (22.0% versus 24.8%, P < 0.001) was lower in PIP compared to DIP. However, the percentage of prescriptions with antibiotics (31.3% versus 14.7%, P < 0.001) was higher in PIP. Conclusion: Paracetamol appears to be preferred mostly in upper respiratory tract infections compared to the preference of diclofenac rather in painful/inflammatory musculoskeletal conditions. The presence of hypertension among the most commonly encountered diagnoses for these analgesic drugs points to challenges in establishing the diagnosing-treatment match and indicates potential irrational prescribing practice, especially for interactions. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Cambridge University Press | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights | Attribution 4.0 International | * |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Analgesic | en_US |
dc.subject | Diclofenac | en_US |
dc.subject | Pain | en_US |
dc.subject | Paracetamol | en_US |
dc.subject | Prescribing | en_US |
dc.subject | Primary Care | en_US |
dc.title | Comparison of paracetamol and diclofenac prescribing preferences for adults in primary care | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Primary Health Care Research & Development | en_US |
dc.department | İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Tıbbi Farmakoloji Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Halk Sağlığı Ana Bilim Dalı | en_US |
dc.authorid | 0000-0001-8984-9673 | en_US |
dc.identifier.volume | 22 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1017/S1463423621000797 | en_US |
dc.identifier.wosquality | Q4 | en_US |
dc.identifier.scopusquality | Q2 | en_US |