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Chemogenetic tools and genetic biosensors in redox biology: Probing Hyper7 signals in specific cellular locales
(Elsevier Science Inc., 2023)
H2O2 is one of the most studied reactive oxygen species (ROS) in redox biology because of its critical role in oxidant-dependent signaling pathways. Conventional approaches apply exogenous H2O2 on cells and tissues, which ...
Importance of physiological oxygen levels for endothelial redox signaling using Hyper 7
(Elsevier Science Inc, 2023)
Cellular redox status is tightly linked to ambient oxygen levels. Endothelial cells (EC) in vivo are exposed to O2 levels between 3- 13 kPa, yet the majority in vitro studies maintain EC under atmospheric O2 levels (~18 ...