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dc.contributor.authorBener, Abdülbari
dc.contributor.authorAğan, Ahmet Faruk
dc.contributor.authorAl-Hamaq, Abdulla Omar A.A.
dc.contributor.authorBarışık, Cem Cahit
dc.contributor.authorÖztürk, Mustafa
dc.contributor.authorÖmer, Abdulkadir
dc.date.accessioned2021-04-06T07:04:22Z
dc.date.available2021-04-06T07:04:22Z
dc.date.issued2020en_US
dc.identifier.citationBener, A., Ağan, A. F., Al-Hamaq, A. O. A.A., Barışık, C. C., Öztürk, M. ve Ömer, A. (2020). Prevalence of helicobacter pylori infection among type 2 diabetes mellitus. Advanced Biomedical Research, 9(1). https://dx.doi.org/10.4103/abr.abr_248_19en_US
dc.identifier.issn2277-9175
dc.identifier.urihttps://dx.doi.org/10.4103/abr.abr_248_19
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6698
dc.description.abstractBackground: Several conducted studies have reported a higher and more frequent Helicobacter pylori infection rate in type 2 diabetes mellitus (T2DM). The aim of this study was to investigate the prevalence and its association between H. pylori infection and T2DM.Materials and methods: A case and control study was conducted based on 529 T2DM patients and 529 control. H. pylori was assessed by Serum anti-H. pylori immunoglobulin G (IgG) and IgA. Furthermore, patients were investigated for fasting blood glucose (FBG) levels, glycosylated hemoglobin (HbA1c), serum cholesterol, and other biochemistry parameters.Results: The findings showed a positive significantly higher antibody titer for H. pylori infection (IgA > 250) in diabetic patients (50.7%) compared to controls (38.2%) (P < 0.001). Similarly, H. pylori infection for IgG > 300 titer was higher in T2DM patients (73.5%) compared to controls 61.8%) (P < 0.001). Further, the mean values were statistically significant diabetes with H. pylori infection for IgG > 300 titer and IgA > 250 titer, regarding Vitamin D, HbA1C (P < 0.001), FBG, calcium, creatinine, total cholesterol, LHDL, triglyceride levels, uric acid, bilirubin, thyroid-stimulating hormone (TSH), and systolic and diastolic blood pressure. The diabetic patients showed higher prevalence rate of symptoms than controls included: hypertension (14.3%), vomiting (15.5%), muscular symptoms (35.2%), bloating/distension (13.2%), abdominal pain (17%), nausea (9.6%), anemia (17%), kidneys (20.8%), chronic bronchitis (14.7%), gastrointestinal (23.8%), and diarrhea (20.4%).Conclusions: The current study revealed that H. pylori infections were significantly higher in diabetic patients compared to controls. Furthermore, T2DM patients infected with H. pylori positive reported a higher prevalence rate of symptoms than H. pylori negative.en_US
dc.language.isoengen_US
dc.publisherMedknow Publications and Media Pvt. Ltd.en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectDiabetesen_US
dc.subjectHelicobacter Pylori Infectionen_US
dc.subjectGlycosylated Hemoglobinen_US
dc.subjectImmunoglobulinen_US
dc.subjectImmunoglobulin Aen_US
dc.subjectImmunoglobulin G.en_US
dc.titlePrevalence of helicobacter pylori infection among type 2 diabetes mellitusen_US
dc.typearticleen_US
dc.relation.ispartofAdvanced Biomedical Researchen_US
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.departmentİstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalıen_US
dc.authorid0000-0002-7902-5803en_US
dc.authorid0000-0003-3540-6492en_US
dc.authorid0000-0003-2209-7694en_US
dc.identifier.volume9en_US
dc.identifier.issue1en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.4103/abr.abr_248_19en_US


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