dc.contributor.author | Bener, Abdülbari | |
dc.contributor.author | Ağan, Ahmet Faruk | |
dc.contributor.author | Al-Hamaq, Abdulla Omar A.A. | |
dc.contributor.author | Barışık, Cem Cahit | |
dc.contributor.author | Öztürk, Mustafa | |
dc.contributor.author | Ömer, Abdulkadir | |
dc.date.accessioned | 2021-04-06T07:04:22Z | |
dc.date.available | 2021-04-06T07:04:22Z | |
dc.date.issued | 2020 | en_US |
dc.identifier.citation | Bener, A., Ağan, A. F., Al-Hamaq, A. O. A.A., Barışık, C. C., Öztürk, M. ve Ömer, A. (2020). Prevalence of helicobacter pylori infection among type 2 diabetes mellitus. Advanced Biomedical Research, 9(1). https://dx.doi.org/10.4103/abr.abr_248_19 | en_US |
dc.identifier.issn | 2277-9175 | |
dc.identifier.uri | https://dx.doi.org/10.4103/abr.abr_248_19 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/6698 | |
dc.description.abstract | Background: Several conducted studies have reported a higher and more frequent Helicobacter pylori infection rate in type 2 diabetes mellitus (T2DM). The aim of this study was to investigate the prevalence and its association between H. pylori infection and T2DM.Materials and methods: A case and control study was conducted based on 529 T2DM patients and 529 control. H. pylori was assessed by Serum anti-H. pylori immunoglobulin G (IgG) and IgA. Furthermore, patients were investigated for fasting blood glucose (FBG) levels, glycosylated hemoglobin (HbA1c), serum cholesterol, and other biochemistry parameters.Results: The findings showed a positive significantly higher antibody titer for H. pylori infection (IgA > 250) in diabetic patients (50.7%) compared to controls (38.2%) (P < 0.001). Similarly, H. pylori infection for IgG > 300 titer was higher in T2DM patients (73.5%) compared to controls 61.8%) (P < 0.001). Further, the mean values were statistically significant diabetes with H. pylori infection for IgG > 300 titer and IgA > 250 titer, regarding Vitamin D, HbA1C (P < 0.001), FBG, calcium, creatinine, total cholesterol, LHDL, triglyceride levels, uric acid, bilirubin, thyroid-stimulating hormone (TSH), and systolic and diastolic blood pressure. The diabetic patients showed higher prevalence rate of symptoms than controls included: hypertension (14.3%), vomiting (15.5%), muscular symptoms (35.2%), bloating/distension (13.2%), abdominal pain (17%), nausea (9.6%), anemia (17%), kidneys (20.8%), chronic bronchitis (14.7%), gastrointestinal (23.8%), and diarrhea (20.4%).Conclusions: The current study revealed that H. pylori infections were significantly higher in diabetic patients compared to controls. Furthermore, T2DM patients infected with H. pylori positive reported a higher prevalence rate of symptoms than H. pylori negative. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Medknow Publications and Media Pvt. Ltd. | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights | Attribution-NonCommercial-ShareAlike 4.0 International | * |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-sa/4.0/ | * |
dc.subject | Diabetes | en_US |
dc.subject | Helicobacter Pylori Infection | en_US |
dc.subject | Glycosylated Hemoglobin | en_US |
dc.subject | Immunoglobulin | en_US |
dc.subject | Immunoglobulin A | en_US |
dc.subject | Immunoglobulin G. | en_US |
dc.title | Prevalence of helicobacter pylori infection among type 2 diabetes mellitus | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Advanced Biomedical Research | en_US |
dc.department | İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı | en_US |
dc.department | İstanbul Medipol Üniversitesi, Uluslararası Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-7902-5803 | en_US |
dc.authorid | 0000-0003-3540-6492 | en_US |
dc.authorid | 0000-0003-2209-7694 | en_US |
dc.identifier.volume | 9 | en_US |
dc.identifier.issue | 1 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.4103/abr.abr_248_19 | en_US |