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dc.contributor.authorZora, Sevilay
dc.contributor.authorYiğitbaşı, Türkan
dc.contributor.authorÜlfer, Gözde
dc.contributor.authorEmekli, Nesrin
dc.date.accessioned2021-01-26T05:37:15Z
dc.date.available2021-01-26T05:37:15Z
dc.date.issued2018en_US
dc.identifier.citationZora, S., Yiğitbaşı, T., Ülfer, G. ve Emekli, N. (2018). Serum concentration of ghrelin, oxidative stress and lipid parameters in obese subjects. European Journal of Biology, 77(2), 55-58. https://doi.org/10.26650/EurJBiol.2018.18008en_US
dc.identifier.issn2602-2575
dc.identifier.issn2618-6144
dc.identifier.urihttps://doi.org/10.26650/EurJBiol.2018.18008
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6382
dc.description.abstractObjective: Ghrelin is a hormone with peptide structure. It has fatty tissue and increases appetite. Obesity is a multifactorial chronic disease characterized by an increase in fat tissue. Fat tissue, like the endocrine organ, triggers oxidative stress and can lead to the development of obesity-related pathologies. The purpose of this study is to examine the relationship between the ghrelin in blood, and oxidative stress and lipid parameters. Materials and Methods: The study was conducted with 61 obese and 24 healthy individuals. Ghreline levels were measured using the ELISA method, while total antioxidant status (TAS) and oxidant status (TOS), triglyceride (TG), total cholesterol (TC), HDL-cholesterol (HDL-C) and LDL cholesterol (LDL-C) levels were measured using the photometric method. Results: A negative correlation was found between body mass index (BMI) and ghrelin levels in the obese group (p<0.05). But there was no significant difference of ghrelin levels in obese and control groups (p>0.05). TAS was observed to be lower in obese compared to control group, while The Oxidative Stress Index (OSI) was found to be significantly higher than the obese group (p<0.05). TG levels were found to be increased in obese; whereas ghrelin, TC, LDL-C and HDL-C levels did not show any difference (p>0.05). Conclusion: Increasing obesity level (BMI) and decreasing ghrelin level were found to be correlated. New studies are needed in order to discover the changes in ghrelin level connected to oxidative stress.en_US
dc.language.isoengen_US
dc.publisherIstanbul University Pressen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGhrelinen_US
dc.subjectObesityen_US
dc.subjectOxidative Stressen_US
dc.titleSerum concentration of ghrelin, oxidative stress and lipid parameters in obese subjectsen_US
dc.typearticleen_US
dc.relation.ispartofEuropean Journal of Biologyen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalıen_US
dc.authorid0000-0002-0675-1839en_US
dc.authorid0000-0003-2350-6381en_US
dc.authorid0000-0002-0109-5086en_US
dc.identifier.volume77en_US
dc.identifier.issue2en_US
dc.identifier.startpage55en_US
dc.identifier.endpage58en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.26650/EurJBiol.2018.18008en_US


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