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dc.contributor.authorZeng, Guohua
dc.contributor.authorZhu, Wei
dc.contributor.authorLam, Wayne
dc.contributor.authorBayramgil, Ayberk
dc.date.accessioned2020-12-03T07:27:57Z
dc.date.available2020-12-03T07:27:57Z
dc.date.issued2020en_US
dc.identifier.citationZeng, G., Zhu, W., Lam, W. ve Bayramgil, A. (2020). Treatment of urinary tract infections in the old and fragile. World Journal of Urology, 38(11), 2709-2720. https://dx.doi.org/10.1007/s00345-020-03159-2en_US
dc.identifier.issn0724-4983
dc.identifier.issn1433-8726
dc.identifier.urihttps://dx.doi.org/10.1007/s00345-020-03159-2
dc.identifier.urihttps://hdl.handle.net/20.500.12511/6074
dc.description.abstractIntroduction Urinary tract infection (UTI) is highly prevalent in the frail elderly population. This review aimed to outline the diagnostic, treatment, and prevention of UTI in the frail aging population. Methods Pubmed and Web of Science search to identify publications until March 2019 relating to the management of UTI in the elderly population was performed. A narrative review of the available literature was performed. Results 64 publications were considered as relevant and included in this review. The diagnosis of symptomatic UTI in the old and fragile could be challenging. Routine screening and antimicrobial therapy for asymptomatic bacteriuria should not be recommended for frail elderly patients. Cautious choice of antibiotics should be guided by uropathogen identified by culture and sensitivity. Understanding local antibiotic resistance rates plays a fundamental part in selecting appropriate antimicrobial treatment. Impact of associated adverse effect, in particular those with effects on cognitive function, should be considered when deciding choice of antibiotics for symptomatic UTI in the elderlies. Optimal management of comorbidities such as diabetes mellitus, adequate treatment of urinary incontinence, and judicious use of urinary catheter is essential to reduce the development of UTI. Conclusion UTI is a significant but common problem in elderly population. Physicians who care for frail elderly patients must be aware of the challenges in the management of asymptomatic UTI, and identifying symptomatic UTI in this population, and their appropriate management strategies. There is strong need in studies to evaluate nonantimicrobial therapies in the prevention of UTI for the frail elderly population.en_US
dc.description.sponsorshipNational Natural Science Foundation of China (NSFC); National Natural Science Foundation of Guangdong Provinceen_US
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectUrinary Infectionen_US
dc.subjectElderlyen_US
dc.subjectFrailen_US
dc.subjectAsymptomatic Bacteriuriaen_US
dc.subjectReviewen_US
dc.titleTreatment of urinary tract infections in the old and fragileen_US
dc.typereviewen_US
dc.relation.journalWorld Journal of Urologyen_US
dc.departmentİstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.authorid0000-0003-1782-7808en_US
dc.identifier.volume38en_US
dc.identifier.issue11en_US
dc.identifier.startpage2709en_US
dc.identifier.endpage2720en_US
dc.relation.publicationcategoryDiğeren_US
dc.identifier.doi10.1007/s00345-020-03159-2en_US


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