Ara
Toplam kayıt 91, listelenen: 11-20
Mechanistic insight into the impact of a bivalent ligand on the structure and dynamics of a GPCR oligomer
(Elsevier B.V., 2022)
Development of effective bivalent ligands has become the focus of intensive research toward modulation of G protein-coupled receptor (GPCR) oligomers, particularly in the field of GPCR pharmacology. Experimental studies ...
Stratification of the gut microbiota composition landscape across the alzheimer's disease continuum in a Turkish cohort
(American Society for Microbiology, 2022)
Alzheimer's disease (AD) is a heterogeneous disorder that spans a continuum with multiple phases, including preclinical, mild cognitive impairment, and dementia. Unlike for most other chronic diseases, human studies reporting ...
Telling functional networks apart using ranked network features stability
(NLM (Medline), 2022)
Over the past few years, it has become standard to describe brain anatomical and functional organisation in terms of complex networks, wherein single brain regions or modules and their connections are respectively identified ...
Enhancing memory capacity by experimentally slowing theta frequency oscillations using combined EEG-tACS
(Nature Portfolio, 2022)
he coupling of gamma oscillation (similar to 40+ Hz) amplitude to the phase of ongoing theta (similar to 6 Hz) oscillations has been proposed to be directly relevant for memory performance. Current theories suggest that ...
An alternative approach wound healing field with polypodium vulgare
(Logos Medical Publishing, 2020)
Objective: In this study, we examined the effects of Polypodium vulgare L. (Polypodiaceae) as a candidate to be used for wound healing scarred area. We investigated the antibacterial, and antioxidant activity of P. Vulgare ...
A co-culture-based multiparametric imaging technique to dissect local H2O2 signals with targeted HyPer7
(MDPI, 2021)
Multispectral live-cell imaging is an informative approach that permits detecting biological processes simultaneously in the spatial and temporal domain by exploiting spectrally distinct biosensors. However, the combination ...
A novel insight into differential expression profiles of sporadic cerebral cavernous malformation patients with different symptoms
(Nature Research, 2021)
Cerebral cavernous malformation (CCM) is a vascular lesion of the central nervous system that may lead to distinct symptoms among patients including cerebral hemorrhages, epileptic seizures, focal neurologic deficits, ...
Therapeutic utility of immunosuppressive TREM2+macrophages: An important step forward in potentiating the immune checkpoint inhibitors
(Springer Nature, 2020)
In a recent article published in Cell, Molgora et al.1 reported that asubset of tumor-infiltrating macrophages with TREM2 expressioncreates an immunosuppressive microenvironment that promotestumor growth while suppressing ...
Adult mouse dorsal root ganglia neurons form aberrant glutamatergic connections in dissociated cultures
(Public Library of Science, 2021)
Cultured sensory neurons can exhibit complex activity patterns following stimulation in terms of increased excitability and interconnected responses of multiple neurons. Although these complex activity patterns suggest a ...
Chemogenetic inhibition of MCH neurons does not alter memory performance in mice
(Elsevier Masson s.r.l., 2022)
Memory storage in the brain is one of the most extensively studied subjects in neuroscience. However, due to the highly complex structure of the memory-related systems in the brain, the mystery remains unsolved. Consolidation ...