Bölüm "İstanbul Medipol Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı" Makale Koleksiyonu için listeleme
Toplam kayıt 6, listelenen: 1-6
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Chronic unpredictable stress disturbs the blood-testis barrier affecting sperm parameters in mice
(Elsevier Ltd, 2021)Research question: Does chronic stress affect the key proteins and sperm parameters of the blood & ndash;testis barrier (BTB)? Design: C57Bl/6 mice were divided into two groups: a non-treated control group and a chronic ... -
Downregulation of Yap1 during limb regeneration results in defective bone formation in axolotl
(Elsevier Inc., 2023)The Hippo pathway plays an imperative role in cellular processes such as differentiation, regeneration, cell migration, organ growth, apoptosis, and cell cycle. Transcription coregulator component of Hippo pathway, YAP1, ... -
The effects of gold nanoparticles with different surface coatings and sizes on biochemical parameters in mice
(Prusa Medical Publishing, 2023)Objectives: Gold nanoparticles are very popular metallic nanomaterials and they have a wide spectrum of biomedical applications. This study was aimed to the production of stable and monodisperse polyethyleneimine (PEI) and ... -
The effects of surface functionality and size of gold nanoparticles on neuronal toxicity, apoptosis, ROS production and cellular/suborgan biodistribution
(Elsevier B.V., 2021)Gold nanoparticles are emerging as promising nanomaterials to create nanoscale therapeutic delivery systems. The aim of the study was to synthesis of highly monodisperse and stable gold nanoparticles functionalized with ... -
The effects of various surface coatings of gold nanorods on toxicity, neuronal localization, microstructural alterations, and in vitro/in vivo biodistribution
(Wiley, 2022)With the development of gold nanorods (AuNRs) for a number of biomedical applications, understanding their various biological effects has become important. Surface functionalization of AuNRs is attracting increasing attention ... -
Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
(Academic Press Inc., 2022)Lithium, in addition to its effect on acute and long-term bipolar disorder, is involved in neuroprotection after ischemic stroke. Yet, its mechanism of action is still poorly understood, which was only limited to its ...