WoS Q Kategorisi "Q1" Makale Koleksiyonu İçin Listeleme
Toplam kayıt 63, listelenen: 41-60
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A novel insight into differential expression profiles of sporadic cerebral cavernous malformation patients with different symptoms
(Nature Research, 2021)Cerebral cavernous malformation (CCM) is a vascular lesion of the central nervous system that may lead to distinct symptoms among patients including cerebral hemorrhages, epileptic seizures, focal neurologic deficits, ... -
Oscillatory delta and theta frequencies differentially support multiple items encoding to optimize memory performance during the digit span task
(Academic Press Inc., 2022)The human brain has limited storage capacity often challenging the encoding and recall of a long series of multiple items. Different encoding strategies are therefore employed to optimize performance in memory processes ... -
Patients with Alzheimer's disease dementia show partially preserved parietal 'hubs' modeled from resting-state alpha electroencephalographic rhythms
(Frontiers Media S.A., 2023)IntroductionGraph theory models a network by its nodes (the fundamental unit by which graphs are formed) and connections. 'Degree' hubs reflect node centrality (the connection rate), while 'connector' hubs are those linked ... -
PEGylated reduced graphene oxide as nanoplatform for targeted gene and drug delivery
(Elsevier Ltd, 2023)Combination therapies involving anticancer drugs and gene therapy agents have become a potential treatment for different cancer types reducing the side effects of anticancer drugs while enhancing their effectiveness. Here, ... -
Porous, columnar shaped iron rich oxide synthesis for lithium-ion batteries from metallurgical grade, domestic, high carbon ferro-chromium alloys
(Elsevier Ltd, 2022)With this article, first time in the open literature, the synthesis, and the characterization of an anode material from a domestic, intermediate product (i.e. ferrochromium alloy) have been carried out. The presented ... -
Potential of novel methyl jasmonate analogs as anticancer agents to metabolically target HK-2 activity in glioblastoma cells
(Frontiers Media S.A., 2022)Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, ... -
Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation
(NLM (Medline), 2023)Background: Stroke stimulates reactive astrogliosis, aquaporin 4 (AQP4) depolarization and neuroinflammation. Preconditioned extracellular vesicles (EVs) from microglia exposed to hypoxia, in turn, reduce poststroke brain ... -
Preconditioning concepts for the therapeutic use of extracellular vesicles against stroke
(Oxford University Press, 2023)Various preclinical stroke models have demonstrated the neuroprotective effects of extracellular vesicles (EVs) obtained from several types of cells, including neurons, astrocytes, microglia, neuronal progenitor cells, ... -
Predicting the effects of repetitive transcranial magnetic stimulation on cognitive functions in patients with alzheimer's disease by automated EEG analysis
(Frontiers Media SA, 2022)Alzheimer's disease (AD) is a progressive, neurodegenerative brain disorder that generally affects the elderly. Today, after the limited benefit of the pharmacological treatment strategies, numerous noninvasive brain ... -
Probing subcellular iron availability with genetically encoded nitric oxide biosensors
(MDPI (Multidisipliner Digital Publishing Institute), 2022)Cellular iron supply is required for various biochemical processes. Measuring bioavailable iron in cells aids in obtaining a better understanding of its biochemical activities but is technically challenging. Existing ... -
A rational design of multi-functional nanoplatform: Fluorescent-based “off-on” theranostic gold nanoparticles modified with D-α-Tocopherol succinate
(Elsevier B.V., 2021)It is crucial to develop nanocarrier systems to detect and treat drug-resistant micro tumors to prevent recurrence and/or metastasis of cancer. Due to their exceptional features such as biocompatibility, easy surface ... -
rTMS reduces delta and increases theta oscillations in Alzheimer's disease: A visual-evoked and event-related potentials study
(Wiley, 2024)Background: Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising alternative therapy for Alzheimer's disease (AD) due to its ability to modulate neural networks and enhance cognitive function. ... -
Social isolation initiated post-weaning augments ischemic brain injury by promoting pro-inflammatory responses
(Academic Press Inc., 2024)Social isolation is associated with poor stroke outcome, but the underlying molecular mechanisms were largely unknown. In male Balb/C mice exposed to transient middle cerebral artery occlusion (MCAo), we examined the effects ... -
Sperm selection with Annexin-V coated polystrene bead technique (APB-Tech): A novel and reliable method for the microscopic selection of viable and non-apoptotic sperm to be used for intracytoplasmic sperm injection
(Elsevier Inc., 2022)Infertility is a growing health problem that affects 20% of couples who want to conceive. ‘Intracytoplasmic sperm injection’ (ICSI) is a commonly used assisted reproduction treatment technique that offers the couples to ... -
Stratification of the gut microbiota composition landscape across the alzheimer's disease continuum in a Turkish cohort
(American Society for Microbiology, 2022)Alzheimer's disease (AD) is a heterogeneous disorder that spans a continuum with multiple phases, including preclinical, mild cognitive impairment, and dementia. Unlike for most other chronic diseases, human studies reporting ... -
A structural and resting-state functional connectivity investigation of the pulvinar in elderly individuals and Alzheimer's disease patients
(John Wiley and Sons Inc, 2023)In Alzheimer's disease (AD), structural and functional changes in the brain may give rise to disruption of specific cognitive functions. The aim of this study is to investigate the functional connectivity alterations in ... -
Telling functional networks apart using ranked network features stability
(NLM (Medline), 2022)Over the past few years, it has become standard to describe brain anatomical and functional organisation in terms of complex networks, wherein single brain regions or modules and their connections are respectively identified ... -
TGF-β1 decreases microglia-mediated neuroinflammation and lipid droplet accumulation in an in vitro stroke model
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Hypoxia triggers reactive microglial inflammation and lipid droplet (LD) accumulation under stroke conditions, although the mutual interactions between these two processes are insufficiently understood. Hence, the involvement ... -
Therapeutic utility of immunosuppressive TREM2+macrophages: An important step forward in potentiating the immune checkpoint inhibitors
(Springer Nature, 2020)In a recent article published in Cell, Molgora et al.1 reported that asubset of tumor-infiltrating macrophages with TREM2 expressioncreates an immunosuppressive microenvironment that promotestumor growth while suppressing ... -
TIM-3/Gal-9 interaction affects glucose and lipid metabolism in acute myeloid leukemia cell lines
(Frontiers Media SA, 2023)Introduction: T-cell immunoglobulin and mucin domain-3 (TIM-3) is a transmembrane molecule first identified as an immunoregulator. This molecule is also expressed on leukemic cells in acute myeloid leukemia and master cell ...