Güncel Gönderiler: Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü (SABİTA)
Toplam kayıt 213, listelenen: 21-40
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Knockdown of NEAT1 prevents post-stroke lipid droplet agglomeration in microglia by regulating autophagy
(Springer Science and Business Media Deutschland GmbH, 2024)Background: Lipid droplets (LD), lipid-storing organelles containing neutral lipids like glycerolipids and cholesterol, are increasingly accepted as hallmarks of inflammation. The nuclear paraspeckle assembly transcript 1 ... -
Integrated multi-omics analyses of microbial communities: A review of the current state and future directions
(Royal Society of Chemistry, 2023)Integrated multi-omics analyses of microbiomes have become increasingly common in recent years as the emerging omics technologies provide an unprecedented opportunity to better understand the structural and functional ... -
Examining the tapestry of mental health crises in low-& middle-income countries: An intercontinental analysis of the contributing factors and instructive approaches
(University of Faisalabad, 2023)In recent decades, the intricate landscape of mental health challenges has become a focal point of global concern, with particular urgency in Low-and Middle-Income Countries (LMICs). This manuscript delves into the ... -
fNIRS-based evaluation of the impact of SARS-CoV-2 infection central auditory processing
(Wiley, 2023)ObjectivesCoronavirus disease-2019 due to SARS-CoV-2 infection has been associated with neurological and neuropsychiatric illnesses as well as auditory system problems. In this study, we aimed to evaluate the impact of ... -
Electroless nickel-plated ferrochromium flue dust as anode material for lithium-ion batteries
(Springer, 2023)The flue dust of the electric arc furnace is a waste product generated in the production of ferrochromium alloy. It consists of various transition metal oxides and silicates. In this study, innovatively, it is proposed to ... -
Age-associated resilience against ischemic injury in mice exposed to transient middle cerebral artery occlusion
(Springer, 2023)Ischemic stroke is the leading cause of death and disability. Although stroke mainly affects aged individuals, animal research is mostly one on young rodents. Here, we examined the development of ischemic injury in young ... -
Centralized healthcare database for ensuring better healthcare: Are we lagging behind?
(Professional Medical Publications, 2024)Database is an organized set of large information gathered and stored electronically to be retrieved whenever required. The systematically stored information can be ... -
TGF-β1 decreases microglia-mediated neuroinflammation and lipid droplet accumulation in an in vitro stroke model
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Hypoxia triggers reactive microglial inflammation and lipid droplet (LD) accumulation under stroke conditions, although the mutual interactions between these two processes are insufficiently understood. Hence, the involvement ... -
A longitudinal study of the association between depression, anxiety and stress symptoms of university students in Serbia with excessive social media use before and during COVID-19 pandemic
(Frontiers Media SA, 2023)Background: Besides the well known good side of social media, it cannot be denied some of its negative effects. This two-phase study aimed to find out whether the usage of social media during the COVID-19 pandemic showed ... -
Poor reactivity of posterior electroencephalographic alpha rhythms during the eyes open condition in patients with dementia due to Parkinson's disease
(Elsevier Inc., 2024)Here, we hypothesized that the reactivity of posterior resting-state electroencephalographic (rsEEG) alpha rhythms during the transition from eyes-closed to -open condition might be lower in patients with Parkinson's disease ... -
Importance of physiological oxygen levels for endothelial redox signaling using Hyper 7
(Elsevier Science Inc, 2023)Cellular redox status is tightly linked to ambient oxygen levels. Endothelial cells (EC) in vivo are exposed to O2 levels between 3- 13 kPa, yet the majority in vitro studies maintain EC under atmospheric O2 levels (~18 ... -
TREM2 regulates microglial lipid droplet formation and represses post-ischemic brain injury
(Elsevier Masson s.r.l., 2024)Triggering receptor expressed on myeloid cells 2 (TREM2) is a transmembrane receptor protein predominantly expressed in microglia within the central nervous system (CNS). TREM2 regulates multiple microglial functions, ... -
Plasmonic titanium nitride nanohole arrays for refractometric sensing
(American Chemical Society, 2023)Group IVB metal nitrides have attracted great interest as alternative plasmonic materials. Among them, titanium nitride (TiN) stands out due to the ease of deposition and relative abundance of Ti compared to those of Zr ... -
Metaproteogenomic analysis of saliva samples from Parkinson's disease patients with cognitive impairment
(Nature Portfolio, 2023)Cognitive impairment (CI) is very common in patients with Parkinson's Disease (PD) and progressively develops on a spectrum from mild cognitive impairment (PD-MCI) to full dementia (PDD). Identification of PD patients at ... -
TIM-3/Gal-9 interaction affects glucose and lipid metabolism in acute myeloid leukemia cell lines
(Frontiers Media SA, 2023)Introduction: T-cell immunoglobulin and mucin domain-3 (TIM-3) is a transmembrane molecule first identified as an immunoregulator. This molecule is also expressed on leukemic cells in acute myeloid leukemia and master cell ... -
Far-infrared treatment of experimental sinusitis in rabbits: A pilot study
(Verduci Publisher, 2023)OBJECTIVE: Thermal therapy has existed for thousands of years and dates back to ancient civilizations such as the Finns, Romans, ancient Chinese, American Indians, and Egyptians. Sun therapy is a form of natural Far Infrared ... -
Preconditioning concepts for the therapeutic use of extracellular vesicles against stroke
(Oxford University Press, 2023)Various preclinical stroke models have demonstrated the neuroprotective effects of extracellular vesicles (EVs) obtained from several types of cells, including neurons, astrocytes, microglia, neuronal progenitor cells, ... -
Morphology-dependent immunomodulatory coating of hydroxyapatite/PEO for magnesium-based bone implants
(2023)One of the most critical issues concerning orthopedic implants is the risk of chronic inflammation, which poses a threat to the bone healing process. Osteo-immunomodulation plays a pivotal role in implant technology by ... -
Development of light and pH-dual responsive self-quenching theranostic SPION to make EGFR overexpressing micro tumors glow and destroy
(Elsevier B.V., 2023)Drug resistant and undetectable tumors easily escape treatment leading metastases and/or recurrence of the lethal disease. Therefore, it is vital to diagnose and destroy micro tumors using simple yet novel approaches. Here, ... -
Adrenergic modulation of melanocortin pathway by hunger signals
(Nature Research, 2023)Norepinephrine (NE) is a well-known appetite regulator, and the nor/adrenergic system is targeted by several anti-obesity drugs. To better understand the circuitry underlying adrenergic appetite control, here we investigated ...