Ara
Toplam kayıt 74, listelenen: 21-30
Phosphorylation of PI3K/Akt at Thr308, but not phosphorylation of MAPK kinase, mediates lithium-induced neuroprotection against cerebral ischemia in mice
(Academic Press Inc., 2022)
Lithium, in addition to its effect on acute and long-term bipolar disorder, is involved in neuroprotection after ischemic stroke. Yet, its mechanism of action is still poorly understood, which was only limited to its ...
Stratification of the gut microbiota composition landscape across the alzheimer's disease continuum in a Turkish cohort
(American Society for Microbiology, 2022)
Alzheimer's disease (AD) is a heterogeneous disorder that spans a continuum with multiple phases, including preclinical, mild cognitive impairment, and dementia. Unlike for most other chronic diseases, human studies reporting ...
Telling functional networks apart using ranked network features stability
(NLM (Medline), 2022)
Over the past few years, it has become standard to describe brain anatomical and functional organisation in terms of complex networks, wherein single brain regions or modules and their connections are respectively identified ...
Enhancing memory capacity by experimentally slowing theta frequency oscillations using combined EEG-tACS
(Nature Portfolio, 2022)
he coupling of gamma oscillation (similar to 40+ Hz) amplitude to the phase of ongoing theta (similar to 6 Hz) oscillations has been proposed to be directly relevant for memory performance. Current theories suggest that ...
Two phases of macrophages: Inducing maturation and death of oligodendrocytes in vitro co-culture
(Elsevier B.V., 2022)
Background: The plasticity of macrophages in the immune response is a dynamic situation dependent on external stimuli. The activation of macrophages both has beneficial and detrimental effects on mature oligodendrocytes ...
Mechanistic insight into impact of phosphorylation on the enzymatic steps of farnesyltransferase
(Wiley, 2022)
Farnesyltransferase (FTase) is a heterodimeric enzyme, which catalyzes covalent attachment of the farnesyl group to target proteins, thus coordinating their trafficking in the cell. FTase has been demonstrated to be highly ...
Chemogenetic inhibition of MCH neurons does not alter memory performance in mice
(Elsevier Masson s.r.l., 2022)
Memory storage in the brain is one of the most extensively studied subjects in neuroscience. However, due to the highly complex structure of the memory-related systems in the brain, the mystery remains unsolved. Consolidation ...
The preamble to the free radical biology and medicine virtual special issue on “Targeting genetic biosensors to intracellular signaling pathways”
(Elsevier Inc., 2022)
Studying biological signaling pathways is key to understanding the various processes within a cell. The science of biological redox regulation is a rapidly growing research area with implications for various disciplines, ...
Porous, columnar shaped iron rich oxide synthesis for lithium-ion batteries from metallurgical grade, domestic, high carbon ferro-chromium alloys
(Elsevier Ltd, 2022)
With this article, first time in the open literature, the synthesis, and the characterization of an anode material from a domestic, intermediate product (i.e. ferrochromium alloy) have been carried out. The presented ...
Nitric oxide biosensor uncovers diminished ferrous iron-dependency of cultured cells adapted to physiological oxygen levels
(Elsevier B.V., 2022)
Iron is an essential metal for cellular metabolism and signaling, but it has adverse effects in excess. The physiological consequences of iron deficiency are well established, yet the relationship between iron supplementation ...