WoS Q Kategorisi "Q2" Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü (SABİTA) İçin Listeleme
Toplam kayıt 53, listelenen: 1-20
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A 3-DoF robotic platform for the rehabilitation and assessment of reaction time and balance skills of MS patients
(Public Library of Science, 2023)The central nervous system (CNS) exploits anticipatory (APAs) and compensatory (CPAs) postural adjustments to maintain the balance. The postural adjustments comprising stability of the center of mass (CoM) and the pressure ... -
Adult mouse dorsal root ganglia neurons form aberrant glutamatergic connections in dissociated cultures
(Public Library of Science, 2021)Cultured sensory neurons can exhibit complex activity patterns following stimulation in terms of increased excitability and interconnected responses of multiple neurons. Although these complex activity patterns suggest a ... -
Age-associated resilience against ischemic injury in mice exposed to transient middle cerebral artery occlusion
(Springer, 2023)Ischemic stroke is the leading cause of death and disability. Although stroke mainly affects aged individuals, animal research is mostly one on young rodents. Here, we examined the development of ischemic injury in young ... -
Alterations of resting-state Gamma frequency characteristics in aging and Alzheimer's disease
(Springer, 2023)Alzheimer's disease (AD) is an important brain disease associated with aging. It involves various functional and structural changes which alter the EEG characteristics. Although numerous studies have found changes in delta, ... -
Biowaste valorization into valuable nanomaterials: Synthesis of green carbon nanodots and anode material for lithium-ion batteries from watermelon seeds
(Elsevier Ltd, 2024)In this study, a solid biowaste watermelon seed is introduced for the first time as an alternative precursor for the production of fluorescent carbon nanodots and nanostructured activated carbon. Firstly, the seeds are ... -
Characterization of FcγRIa (CD64) as a ligand molecule for site-specific IgG1 capture: A side-by-side comparison with protein a
(American Chemical Society, 2022)Fc γreceptors (FcγRs) are one of the structures that can initiate effector function for monoclonal antibodies. FcγRIa has the highest affinity toward IgG1-type monoclonal antibodies among all FcγRs. In this study, a ... -
Chemogenetic approaches to dissect the role of H2O2 in redox-dependent pathways using genetically encoded biosensors
(Portland Press Ltd, 2022)Chemogenetic tools are recombinant enzymes that can be targeted to specific organelles and tissues. The provision or removal of the enzyme substrate permits control of its biochemical activities. Yeast-derived enzyme D-amino ... -
Classification of Parkinson's disease with dementia using phase locking factor of event-related oscillations to visual and auditory stimuli
(IOP Publishing Ltd, 2023)Objective. In the last decades, machine learning approaches have been widely used to distinguish Parkinson’s disease (PD) and many other neuropsychiatric diseases. They also speed up the clinicians and facilitate decision-making ... -
Combined segmentation and classificationbased approach to automated analysis of biomedical signals obtained from calcium imaging
(Public Library of Science, 2023)Automated screening systems in conjunction with machine learning-based methods are becoming an essential part of the healthcare systems for assisting in disease diagnosis. Moreover, manually annotating data and hand-crafting ... -
Comparison of S gene mutations in patients with occult and chronic hepatitis B virus infection
(Elsevier B.V., 2022)Background and aim: This study aimed to detect mutations in the HBV S gene and evaluate their relationship to occult hepatitis B virus (HBV) infection (OBI). Methods: The study included 32 patients with negative serum HBsAg ... -
Cytotoxic activity and docking studies of 2-arenoxybenzaldehyde N-acyl hydrazone and 1,3,4-oxadiazole derivatives against various cancer cell lines
(MDPI, 2022)To understand whether previously synthesized novel hydrazone and oxadiazole derivatives have promising anticancer effects, docking studies and in vitro toxicity assays were performed on A-549, MDA-MB-231, and PC-3 cell ... -
Design and synthesis of novel caffeic acid phenethyl ester (CAPE) derivatives and their biological activity studies in glioblastoma multiforme (GBM) cancer cell lines
(Elsevier Inc., 2022)Glioblastoma Multiforme (GBM) is the most aggressive brain tumor and classified as one of the deadliest cancers. The current treatment plans for GBM remains to be ineffective because of its rapid progress and inability of ... -
Developing a novel tool to assess the ability to self-administer medication - A systematic evaluation of patients' video recordings in the ABLYMED study
(Frontiers Media S.A., 2023)Background: Older people often experience medication management problems due to multimorbidity, polypharmacy and medication complexity. There is often a large gap between patients' self-reported and actual abilities to ... -
Downregulation of Yap1 during limb regeneration results in defective bone formation in axolotl
(Elsevier Inc., 2023)The Hippo pathway plays an imperative role in cellular processes such as differentiation, regeneration, cell migration, organ growth, apoptosis, and cell cycle. Transcription coregulator component of Hippo pathway, YAP1, ... -
Dual action of exosomes derived from in vitro A beta toxicity model: The role of age for pathological response
(Elsevier Ireland Ltd, 2023)Exosomes released from different cell types of the central nervous system play an essential role in the patho-genesis of Alzheimer's disease (AD). In this study, we aimed to create an animal model by injecting exosomes ... -
The effects of increased glucose level and glycolysis on SARS CoV-2 infection
(Bentham Science Publishers, 2022)COVID-19 has entered our lives as an infection with high mortality rates. Although the vaccination process has provided benefits, the death toll remains frightening worldwide. Therefore, drugs and combined therapies that ... -
The effects of repetitive transcranial magnetic stimulation and aerobic exercise on cognition, balance and functional brain networks in patients with Alzheimer's disease
(Springer, 2023)The purpose of this study was to investigate the effects of high-frequency repetitive Transcranial Magnetic Stimulation (rTMS) and aerobic exercises (AE) in addition to the pharmacological therapy (PT) in Alzheimer's Disease ... -
The effects of transcranial focused ultrasound stimulation of nucleus accumbens on neuronal gene expression and brain tissue in high alcohol-preferring rats
(Springer, 2023)We investigated the effect of low-intensity focused ultrasound (LIFU) on gene expression related to alcohol dependence and histological effects on brain tissue. We also aimed at determining the miRNA-mRNA relationship and ... -
The effects of various surface coatings of gold nanorods on toxicity, neuronal localization, microstructural alterations, and in vitro/in vivo biodistribution
(Wiley, 2022)With the development of gold nanorods (AuNRs) for a number of biomedical applications, understanding their various biological effects has become important. Surface functionalization of AuNRs is attracting increasing attention ... -
Effects of whey Protein, Omega-3 Fatty Acid and Roux-En-Y gastric bypass on body weight, biochemical parameters and organ functions in an obese rat model: Experimental research
(Springer, 2023)Purpose: Extreme obesity (EO) is one of the biggest public health problems in the world and has grown considerably over the years. The aim of the study is to examine the effect of Roux-en-Y gastric bypass (RYGB), whey ...