Başlık için Sağlık Bilim ve Teknolojileri Araştırma Enstitüsü (SABİTA) listeleme
Toplam kayıt 208, listelenen: 189-208
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Telling functional networks apart using ranked network features stability
(NLM (Medline), 2022)Over the past few years, it has become standard to describe brain anatomical and functional organisation in terms of complex networks, wherein single brain regions or modules and their connections are respectively identified ... -
Temperature and pH-dependent behaviors of mAb drugs: A case study for trastuzumab
(MDPI, 2022)The distortions in the high-order structure of therapeutic monoclonal antibodies (mAbs) under different environmental conditions acutely affect mAb stability, resulting in altered safety, efficacy, and shelf-life profiles. ... -
TGF-β1 decreases microglia-mediated neuroinflammation and lipid droplet accumulation in an in vitro stroke model
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Hypoxia triggers reactive microglial inflammation and lipid droplet (LD) accumulation under stroke conditions, although the mutual interactions between these two processes are insufficiently understood. Hence, the involvement ... -
Therapeutic role of repetitive transcranial magnetic stimulation in Alzheimer's and Parkinson's disease: Electroencephalography microstate correlates
(Frontiers Media SA, 2022)Introduction: The microstate analysis is a method to convert the electrical potentials on the multi-channel electrode array to topographical electroencephalography (EEG) data. Repetitive transcranial magnetic stimulation ... -
Therapeutic utility of immunosuppressive TREM2+macrophages: An important step forward in potentiating the immune checkpoint inhibitors
(Springer Nature, 2020)In a recent article published in Cell, Molgora et al.1 reported that asubset of tumor-infiltrating macrophages with TREM2 expressioncreates an immunosuppressive microenvironment that promotestumor growth while suppressing ... -
TIM-3/Gal-9 interaction affects glucose and lipid metabolism in acute myeloid leukemia cell lines
(Frontiers Media SA, 2023)Introduction: T-cell immunoglobulin and mucin domain-3 (TIM-3) is a transmembrane molecule first identified as an immunoregulator. This molecule is also expressed on leukemic cells in acute myeloid leukemia and master cell ... -
TIM-3/Galectin-9 interaction and glutamine metabolism in AML cell lines, HL-60 and THP-1
(BioMed Central Ltd, 2024)Background: T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is a cell surface molecule that was first discovered on T cells. However, recent studies revealed that it is also highly expressed in acute myeloid ... -
Transcranial Magnetic Stimulation (TMS) applications in Alzheimer's disease: A systematic review
(Bezmialem Vakıf University, 2021)Alzheimer's disease (AD), is characterized by its progressive feature and loss of cognitive functions, is common among dementia types. There is no curative treatment of the disease today. In recent years, transcranial ... -
A transcriptome based approach to predict candidate drug targets and drugs for Parkinson's disease using an in vitro 6-OHDA model
(Royal Society of Chemistry, 2023)The most common treatment strategies for Parkinson's disease (PD) aim to slow down the neurodegeneration process or control the symptoms. In this study, using an in vitro PD model we carried out a transcriptome-based drug ... -
TREM2 regulates microglial lipid droplet formation and represses post-ischemic brain injury
(Elsevier Masson s.r.l., 2024)Triggering receptor expressed on myeloid cells 2 (TREM2) is a transmembrane receptor protein predominantly expressed in microglia within the central nervous system (CNS). TREM2 regulates multiple microglial functions, ... -
Two phases of macrophages: Inducing maturation and death of oligodendrocytes in vitro co-culture
(Elsevier B.V., 2022)Background: The plasticity of macrophages in the immune response is a dynamic situation dependent on external stimuli. The activation of macrophages both has beneficial and detrimental effects on mature oligodendrocytes ... -
Two rare autosomal recessive neurological disorders identified by combined genetic approaches in a single consanguineous family with multiple offspring
(2024)Introduction: Neurodevelopmental disorders (NDDs) refer to a broad range of diseases including developmental delay, intellectual disability, epilepsy, autism spectrum disorders, and attention-deficit/hyperactivity disorder ... -
The unconventional growth factors cerebral dopamine neurotrophic factor and mesencephalic astrocyte-derived neurotrophic factor promote post-ischemic neurological recovery, perilesional brain remodeling, and lesion-remote axonal plasticity
(Springer, 2023)Considerable efforts are currently made to develop strategies that boost endogenous recovery once a stroke has occurred. Owing to their restorative properties, neurotrophic factors are attractive candidates that capitalize ... -
Unravelling the impact of COVID-19 on pregnancy: In aspect of placental histopathology and umbilical cord macrophage immunoactivity with neonatal outcomes
(Elsevier Ireland Ltd, 2024)COVID-19 has turned into a global pandemic since it was first detected in 2019, causing serious public health problems. Our objective was to investigate the impact of COVID-19 on pregnant women and newborns, who belong to ... -
Upcycling of industrial iron scale waste for reutilization as anode material in lithium ion batteries
(Elsevier Ltd, 2022)In this work, iron scale is used as the starting raw material to produce anode for lithium ion batteries. In this scope, three different samples are fabricated, then their properties are investigated to evaluate their ... -
Üstün zekâlı çocukların annelerinin gebelik sürecindeki beslenme alışkanlıklarının saptanması: Retrospektif bir çalışma
(Türkiye Klinikleri, 2023)Amaç: Bu araştırmada, üstün zekâlı çocuğu olan annelerin gebelik dönemindeki beslenme al ışkanlıklarının araştırılması ve kontrol grubu ile karşılaştırılması amaçlanmıştır. Gereç ve Yöntemler: Retrospektif ve ta- nımlayıcı ... -
What a single electroencephalographic (EEG) channel can tell us about patients with dementia due to Alzheimer's disease
(Elsevier B.V., 2022)Abnormalities in cortical sources of resting-state eyes-closed electroencephalographic (rsEEG) rhythms recorded by hospital settings (10–20 electrode montage) with 19 scalp electrodes provide useful markers of neurophysiological ... -
Working from home during the COVID-19 pandemic and its effects on diet, sedentary lifestyle, and stress
(MDPI, 2022)Many companies switched to working from home (WFH) after the COVID-19 pandemic. This paper aimed to examine the changes in dietary behavior, body weight, sedentary lifestyle, and stress in individuals who practice WFH. A ... -
Wound healing activity of arum maculatum
(Istanbul Medeniyet University, 2023)Objective: In this study, the antioxidant properties of Arum maculatum plant were evaluated. This study reported for the first time the wound healing activity of the methanol extract of A. maculatum fruits. This study aimed ... -
Zero-valent iron nanoparticles containing nanofiber scaffolds for nerve tissue engineering
(Wiley, 2020)Regeneration of nerve tissue is a challenging issue in regenerative medicine. Especially, the peripheral nerve defects related to the accidents are one of the leading health problems. For large degeneration of peripheral ...
