dc.contributor.author | Atağ, Emine | |
dc.contributor.author | Baş İkizoğlu, Nilay | |
dc.contributor.author | Ergenekon, Pınar | |
dc.contributor.author | Kalın, Sevinç | |
dc.contributor.author | Ünal, Füsun | |
dc.contributor.author | Gökdemir, Yasemin | |
dc.contributor.author | Erdem Eralp, Ela | |
dc.contributor.author | Yalçın, Koray | |
dc.contributor.author | Öktem, Sedat | |
dc.contributor.author | Ersu, Refika | |
dc.contributor.author | Karakoç, Fazilet | |
dc.contributor.author | Karadağ, Bülent | |
dc.date.accessioned | 2020-10-21T11:59:01Z | |
dc.date.available | 2020-10-21T11:59:01Z | |
dc.date.issued | 2020 | en_US |
dc.identifier.citation | Atağ, E., Baş İkizoğlu, N., Ergenekon, P., Kalın, S., Ünal, F., Gökdemir, Y. ... Karadağ, B. (2020). Health-related quality of life in patients with bronchiolitis obliterans. Pediatric Pulmonology, 55(9), 2361-2367. https://dx.doi.org/10.1002/ppul.24896 | en_US |
dc.identifier.issn | 8755-6863 | |
dc.identifier.issn | 1099-0496 | |
dc.identifier.uri | https://dx.doi.org/10.1002/ppul.24896 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12511/5956 | |
dc.description.abstract | Introduction Bronchiolitis obliterans (BO) is mainly caused by infections and hematopoietic stem cell transplantation (HSCT). This study aimed to investigate the health-related quality of life (HRQOL) of children with BO compared to the healthy children and also to assess the HRQOL according to the etiology. Methods Postinfectious (group 1) and post-HSCT BO (group 2) patients and healthy children were included in the study. HRQOL was assessed by the Short Form-36 (SF-36) and St George's Respiratory Questionnaire (SGRQ). Correlations between demographic and clinical characteristics, pulmonary function tests, high-resolution chest tomography scores, and HRQOL were assessed. Results Thirty-seven postinfectious and post-HSCT BO patients and 34 healthy children were included in the study. Mean age was 13.8 +/- 0.7 years. Mean forced vital capacity and forced expiratory volume(1)were 60.7 +/- 2.7% predicted, and 49.8 +/- 3.1% predicted, respectively. The SF-36 scores were lower in BO patients compared to healthy children (P < .01). Patients with better lung functions had higher SF-36 scores, but lower SGRQ. The number of inhaled therapies, acute exacerbations, hospitalizations were inversely correlated with SF-36. A positive correlation was found between these parameters and total SGRQ scores (r = .507,P = .02;r = .409,P = .12;r = .326,P = .049, respectively). SF-36 scores were better in group 1 for subscales of physical role functioning and social role functioning compared to group 2. (P = .01,P = .01, respectively). Conclusion The HRQOL of patients with BO measured by SF-36 was low compared to healthy children. SF-36 scores were more affected in post-HSCT BO patients. HRQOL of children with chronic lung disease should be taken into consideration in the management of these patients. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley | en_US |
dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
dc.subject | Bronchiolitis Obliterans | en_US |
dc.subject | Children | en_US |
dc.subject | Quality of Life | en_US |
dc.title | Health-related quality of life in patients with bronchiolitis obliterans | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Pediatric Pulmonology | en_US |
dc.department | İstanbul Medipol Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | en_US |
dc.authorid | 0000-0003-3105-0409 | en_US |
dc.authorid | 0000-0002-7950-2067 | en_US |
dc.identifier.volume | 55 | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.startpage | 2361 | en_US |
dc.identifier.endpage | 2367 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.doi | 10.1002/ppul.24896 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.identifier.scopusquality | Q1 | en_US |