Association of severity of helicobacter pylori infection with peripheral blood neutrophil to lymphocyte ratio and mean platelet volume
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CitationGüçlü, M. ve Agan, A. F. (2017). Association of severity of helicobacter pylori infection with peripheral blood neutrophil to lymphocyte ratio and mean platelet volume. Euroasian Journal of Hepato-Gastroenterology, 7(1), 11-16. https://dx.doi.org/10.5005/jp-journals-10018-1204
Aim: To determine the correlation of Helicobacter pylori infection with peripheral blood neutrophil/lymphocyteratio (NLR) and mean platelet volume (MPV).Materials and methods: The NLR, MPV, platelets, leukocytes, neutrophils, and lymphocytes were calculatedand the differences between groups were investigated.Results: A total of 199 patients were included in the study. Neutrophil/lymphocyte ratio was statistically lower inH. pylori-positive patients than in H. pylori-negative patients (1.94 ± 0.79 vs 2.67 ± 2.35 respectively, p = 0.04).There was no significant difference between H. pylori-negative patients and H. pylori-positive patients of severeintensity in terms of MPV. However, peripheral blood lymphocytes and platelets were statistically significantlyhigher in H. pylori-positive patients of severe intensity (lymphocytes 2150 ± 826 vs 2954 ± 2436 respectively,p = 0.000 and platelets 258247 ± 69494 vs 265611 ± 113397 respectively, p = 0.02) compared with H. pylorinegative patients.Conclusion: A moderate increase in the intensity of H. pylori does not lead to a significant change in MPV asmeasured by hemogram; however, it gives rise to a statistically significant fall in NLR. Presence of severe H.pylori-positive intensity leads to a statistically significant increase in peripheral blood lymphocytes and plateletscompared with H. pylori-negative patients.
SourceEuroasian Journal of Hepato-Gastroenterology
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