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Toplam kayıt 78, listelenen: 51-60
Minocycline increases in-vitro cortical neuronal cell survival after laser induced axotomy
(2020)
Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials are challenging. ...
Dose-dependent neuroprotective effect of enoxaparin on cold-induced traumatic brain injury
(Medknow Publications & Media Pvt Ltd., 2017)
Recent evidence exists that enoxaparin can reduce brain injury because of its anticoagulant activity. To investigate the potential therapeutic effect of enoxaparin on cold-induced traumatic brain injury, at 20 minutes after ...
Toward a personalized medicine in wake-up stroke?
(Bentham Science Publishers Ltd., 2017)
Ischemic stroke (IS), especially wake-up stroke, is reported to occur with a maximal peak in the morning hoursand usually associated with worse clinical outcome [1-3].Many proposed mechanisms are reported to be responsiblefor ...
Inhibition of fatty acid synthesis aggravates brain injury, reduces blood-brain barrier integrity and impairs neurological recovery in a murine stroke model
(Frontiers Media SA, 2021)
Inhibition of fatty acid synthesis (FAS) stimulates tumor cell death and reduces angiogenesis. When SH-SY5Y cells or primary neurons are exposed to hypoxia only, inhibition of FAS yields significantly enhanced cell injury. ...
HMG-CoA reductase inhibition promotes neurological recovery, peri-lesional tissue remodeling, and contralesional pyramidal tract plasticity after focal cerebral ischemia
(Frontiers Research Foundation, 2014)
3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors are widely used for secondary stroke prevention. Besides their lipid-lowering activity, pleiotropic effects on neuronal survival, angiogenesis, and ...
Acute and post-acute neuromodulation induces stroke recovery by promoting survival signaling, neurogenesis, and pyramidal tract plasticity
(Frontiers Media Sa, 2019)
Repetitive transcranial magnetic stimulation (rTMS) has gained interest as a non-invasive treatment for stroke based on the data promoting its effects on functional recovery. However, the exact action mechanisms by which ...
The brain protective effect of rtms (repetitive transcranial magnetic stimulation) in depression: A mini-review in animal studies
(Bentham Science Publishers, 2016)
There are rapidly replicating human data suggesting the therapeutic and neurorestorative role of repetitive transcranial magnetic stimulation (rTMS) in clinical depression. However there are only limited experimental studies ...
The neuroprotective role of vesicular monoamine transporter 2 in neurodegenerative diseases
(Bentham Science Publishers, 2015)
Neuropharmacological relation of religious belief supports the role of dopaminergic activation as the leading neurochemical feature. However, vesicular monoamine transporter-2 (VMAT-2) has been shown to be responsible for ...
Evaluation of light-emitting diode photobiomodulation on bone healing of rat calvarial defects
(Taylor & Francis, 2015)
One of the major problems in modern dentistry is the recovery of bone defects. The aim of this prospective experimental study was to evaluate the effect of light-emitting diode (LED) photobiomodulation therapy on bone ...
Focused ultrasound and NXY-059 in experimental cerebral ischemia: A new therapeutic opportunity?
(Bentham Science Publishers, 2016)
troke is the third leading cause of morbidity and mortality worldwide. Many deleterious cellular pathways have been proposed to explain the molecular pathogenesis of this clinically devastating disease [1, 2]. The ...