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Toplam kayıt 30, listelenen: 21-30
Reply to the letter to the author concerning: 'Does adenoid hypertrophy affect disease severity in children with allergic rhinitis?'
(Springer, 2018)
We would like to thank the author for making valuable comments about our article entitled “Does adenoid hypertrophy affect disease severity in children with allergic rhinitis?” [1]. However, we think that the reviewer has ...
Clinical presentation and cranial mri findings of listeria monocytogenes encephalitis a literature review of case series
(Lippincott Williams & Wilkins, 2018)
Background: Listeria monocytogenes-associated encephalitis is a severe clinical condition that can also be seen in immunocompetent patients. Clinical manifestation and radiologic features of this entity need to be elaborated. ...
The effect of the cerclage wire in the treatment of subtrochanteric femur fracture with the long proximal femoral nail: A review of 52 cases
(Elsevier Science Bv, 2018)
Introduction: To present the effect of the cerclage fixation, which was performed for the purpose of preserving the alignment obtained by open reduction, on the long-term clinical and radiological results of subtrochanteric ...
Modulation of protein-protein interactions for the development of effective therapeutics - from a joint perspective of experiment and computation
(Bentham Science Publishers B.V., 2018)
Many proteins present in living organisms act as obligate oligomers – that is to say - they require other protein partners to function properly. Oligomerization does not only lead to the formation of physical interactions, ...
Computational approaches in antibody-drug conjugate optimization for targeted cancer therapy
(Bentham Science Publishers Ltd, 2018)
Cancer has become one of the main leading causes of morbidity and mortality worldwide. One of the critical drawbacks of current cancer therapeutics has been the lack of the target-selectivity, as these drugs should have ...
Prediction and targeting of interaction interfaces in g-rotein coupled receptor oligomers
(Bentham Science Publishers Ltd, 2018)
Background: Communication within a protein complex is mediated by physical interactions made among the protomers. Evidence for both the allosteric regulation present among the protomers of the protein oligomer and of the ...
Beyond the therapeutic effect of RTMS in Alzheimer’s disease: A possible neuroprotective role of hippocampal BDNF?: A minireview
(Bentham Science Publishers B.V., 2018)
Repetitive transcranial magnetic stimulation (rTMS) is a well known non-invasive brain stimulation procedure which is capable of inducing the expression of the hippocampal BDNF that has been already shown to exert significant ...
Positioning Europe for the epitranscriptomics challenge
(Taylor and Francis Inc., 2018)
The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C,A,G, and U in RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins of all organisms are built. ...
Therapeutic role of rifampicin in Alzheimer's disease
(Wiley, 2018)
Rifampicin exerts significant brain protective functions in multiple experimental models. Here we summarize the underlying mechanisms of the neuroprotective and pro-cognitive effects of rifampicin that are mediated by its ...
More evidence for the therapeutic role of pramipexole in upper limb restlessness due to cervical disc pathology?
(Bentham Science Publ Ltd, 2018)
Background: The causal link between upper limb restlessness and cervical disc prolapsus is still unclear, and the exact role of the spinal cord in the origination of limb restlessness is not yet completely understood. ...