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Oxytocin antagonists: The next frontier in PE treatment
(Nature Publishing Group, 2019)
Oxytocin antagonists seem to have potential as a treatment option for premature ejaculation (PE), but the parameters of their use are vague. Two recently published studies highlight the need for large-scale trials to ...
Bilateral oropharyngeal hairy polyps: A rare cause of dyspnea in newborns
(Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2017)
Hairy polyp (HP) is one of the causes of congenital dyspnea, a rare developmental malformation of bigerminal origin that comprises both ectodermal and mesodermal elements foreign to the site in which it is found. It typically ...
eComment. Prompt decision making on the site of surgical approach in patients with chest trauma-a brief communication
(Oxford University Press, 2014)
We read with great interest the article by Chen et al. [1]. Haemothorax is an important finding in trauma patients, which may either be a self-limited condition or the evidence of a life-threatening injury to the thoracic ...
Modulation of protein-protein interactions for the development of effective therapeutics - from a joint perspective of experiment and computation
(Bentham Science Publishers B.V., 2018)
Many proteins present in living organisms act as obligate oligomers – that is to say - they require other protein partners to function properly. Oligomerization does not only lead to the formation of physical interactions, ...
Non-traumatic L4-L5 spondyloptosis
(Elsevier Science Inc, 2016)
A 28-year-old female patient suffering from low back painand bilateral leg numbness was referred to an orthopedic clinicfor correction of scoliosis. She had congenital skeletal deformities and also scoliosis with no history ...
What is hot and new in basic science in liver transplantation in 2018? Report of the basic science committee of the international liver transplantation society
(NLM (Medline), 2019)
The 2018 Joint International Congress of the International Liver Transplantation Society (ILTS), European Liver and Intestine Transplant Association, and Liver Intensive Care Group of Europe meeting was held in Lisbon, ...
A different view on the pathophysiology of Parkinson’s disease: A descendent neurochemical hypothesis?
(Wolters Kluwer, 2019)
It has been already shown that Parkinson’s disease (PD) is characterized by a prominent degeneration in substantia nigra (SN)neurons. Growing evidence suggests that there is a latent period of PD associated with slight ...
Focused ultrasound and NXY-059 in experimental cerebral ischemia: A new therapeutic opportunity?
(Bentham Science Publishers, 2016)
troke is the third leading cause of morbidity and mortality worldwide. Many deleterious cellular pathways have been proposed to explain the molecular pathogenesis of this clinically devastating disease [1, 2]. The ...
Positioning Europe for the epitranscriptomics challenge
(Taylor and Francis Inc., 2018)
The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C,A,G, and U in RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins of all organisms are built. ...