Ara
Toplam kayıt 32, listelenen: 21-30
Specific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia
(Pergamon Elsevier Science Ltd, 2018)
Sirtuins have gained considerable attention as epigenetic regulators for slowing aging and age-related disorders. The growing association between neurodegeneration and inflammation has led researchers to investigate ...
The neuroprotective effect of focused ultrasound: New perspectives on an old tool
(Pergamon-Elsevier Science Ltd., 2017)
Introduction Transcranial focused ultrasound (tFUS) is a novel technique that can noninvasively modulate the cortical function. Moreover, there are rapidly replicating evidence suggesting the role of tFUS for targeted ...
A different view on the platelet aggregation inhibitor clopidogrel - a well-suitable anti-oedema agent in a preclinical model of brain injury?
(Czech Medical Soc, 2019)
Aim: The neuroprotective effects of clopidogrel have already been shown in various experimental models. Taking into account the fact that clopidogrel is well tolerated and approved for use in various clinical settings, it ...
Effects of erythropoietin on spontaneous and oxytocin induced myometrial contractions in the nonpregnant rat
(Verduci Publisher, 2017)
OBJECTIVE: Erythropoietin (EPO) is a glycoprotein hormone that regulates erythropoiesis. EPO activity has also been detected in a variety of tissue including the nervous system, and female and male reproductive organs. It ...
Inflammatory cytokines are in action: Brain plasticity and recovery after brain ischemia due to delayed melatonin administration
(W.B. Saunders, 2021)
Objectives: Post-ischemic inflammation leads to apoptosis as an indirect cause of functional disabilities after the stroke. Melatonin may be a good candidate for the stroke recovery because of its anti-inflammatory effects. ...
Minocycline increases in-vitro cortical neuronal cell survival after laser induced axotomy
(2020)
Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials are challenging. ...
Toward a personalized medicine in wake-up stroke?
(Bentham Science Publishers Ltd., 2017)
Ischemic stroke (IS), especially wake-up stroke, is reported to occur with a maximal peak in the morning hoursand usually associated with worse clinical outcome [1-3].Many proposed mechanisms are reported to be responsiblefor ...
Postacute effects of kisspeptin-10 on neuronal injury induced by L-methionine in rats
(Wiley-Blackwell, 2014)
Apart from its effect on the regulation of reproductive function, recent studies indicate that kisspeptin may play roles in the antioxidant defense system. The antioxidant defense system and oxidative stress contribute to ...
Sustained neurological recovery induced by resveratrol is associated with angioneurogenesis rather than neuroprotection after focal cerebral ischemia
(Academic Press, 2015)
According to the French paradox, red wine consumption reduces the incidence of vascular diseases even in the presence of highly saturated fatty acid intake. This phenomenon is widely attributed to the phytoalexin resveratrol, ...
Phosphodiesterase 10A deactivation induces long-term neurological recovery, peri-infarct remodeling and pyramidal tract plasticity after transient focal cerebral ischemia in mice
(Academic Press Inc., 2022)
The phosphodiesterase (PDE) superfamily comprises enzymes responsible for the cAMP and cGMP degradation to AMP and GMP. PDEs are abundant in the brain, where they are involved in several neuronal functions. High PDE10A ...