Ara
Toplam kayıt 75, listelenen: 51-60
Minocycline increases in-vitro cortical neuronal cell survival after laser induced axotomy
(2020)
Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials are challenging. ...
Cinnamon polyphenol extract exerts neuroprotective activity in traumatic brain injury in male mice
(Bentham Science Publishers Ltd, 2018)
Introduction: Cinnamon polyphenol extract is a traditional spice commonly used in different areas of the world for the treatment of different disease conditions which are associated with inflammation and oxidative stress. ...
Dose-dependent neuroprotective effect of enoxaparin on cold-induced traumatic brain injury
(Medknow Publications & Media Pvt Ltd., 2017)
Recent evidence exists that enoxaparin can reduce brain injury because of its anticoagulant activity. To investigate the potential therapeutic effect of enoxaparin on cold-induced traumatic brain injury, at 20 minutes after ...
Inhibition of fatty acid synthesis aggravates brain injury, reduces blood-brain barrier integrity and impairs neurological recovery in a murine stroke model
(Frontiers Media SA, 2021)
Inhibition of fatty acid synthesis (FAS) stimulates tumor cell death and reduces angiogenesis. When SH-SY5Y cells or primary neurons are exposed to hypoxia only, inhibition of FAS yields significantly enhanced cell injury. ...
Pleiotropic and renoprotective effects of erythropoietin beta on experimental diabetic nephropathy model
(Karger, 2016)
Background: This study aimed at investigating the possible protective effect of erythropoietin beta on experimental diabetic nephropathy (DN) model in rats. Methods: Sprague Dawley rats (n = 32) were allocated into 4 equal ...
HMG-CoA reductase inhibition promotes neurological recovery, peri-lesional tissue remodeling, and contralesional pyramidal tract plasticity after focal cerebral ischemia
(Frontiers Research Foundation, 2014)
3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors are widely used for secondary stroke prevention. Besides their lipid-lowering activity, pleiotropic effects on neuronal survival, angiogenesis, and ...
Acute and post-acute neuromodulation induces stroke recovery by promoting survival signaling, neurogenesis, and pyramidal tract plasticity
(Frontiers Media Sa, 2019)
Repetitive transcranial magnetic stimulation (rTMS) has gained interest as a non-invasive treatment for stroke based on the data promoting its effects on functional recovery. However, the exact action mechanisms by which ...
The neuroprotective role of vesicular monoamine transporter 2 in neurodegenerative diseases
(Bentham Science Publishers, 2015)
Neuropharmacological relation of religious belief supports the role of dopaminergic activation as the leading neurochemical feature. However, vesicular monoamine transporter-2 (VMAT-2) has been shown to be responsible for ...
Evaluation of light-emitting diode photobiomodulation on bone healing of rat calvarial defects
(Taylor & Francis, 2015)
One of the major problems in modern dentistry is the recovery of bone defects. The aim of this prospective experimental study was to evaluate the effect of light-emitting diode (LED) photobiomodulation therapy on bone ...
ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury
(Nature Research, 2022)
Platelet activation plays a critical role in thrombosis. Inhibition of platelet activation is a cornerstone in treatment of acute organ ischemia. Platelet ACKR3 surface expression is independently associated with all-cause ...